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TWO SIGMA INVESTMENTS, LP
> EIGR
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | Eiger BioPharmaceuticals, Inc. | EIGR | 42,200 | -23,800 | 29,709,000 | -29,486,000 | $704.00 |
| 03/31/2023 | Eiger BioPharmaceuticals, Inc. | EIGR | 66,000 | -222,340 | 59,195,000 | -281,046,000 | $896.89 |
| 12/31/2022 | Eiger BioPharmaceuticals, Inc. | EIGR | 288,340 | 226,376 | 340,241,000 | 339,851,000 | $1,180.00 |
| 06/30/2022 | Eiger BioPharmaceuticals, Inc. | EIGR | 61,964 | 34,872 | 390,000 | 165,000 | $6.29 |
| 03/31/2022 | Eiger BioPharmaceuticals, Inc. | EIGR | 27,092 | 27,092 | 225,000 | 225,000 | $8.31 |
| 12/31/2021 | Eiger BioPharmaceuticals, Inc. | EIGR | 0 | -27,027 | 0 | -181,000 | |
| 09/30/2021 | Eiger BioPharmaceuticals, Inc. | EIGR | 27,027 | -7,005 | 181,000 | -109,000 | $6.70 |
| 06/30/2021 | Eiger BioPharmaceuticals, Inc. | EIGR | 34,032 | -144,135 | 290,000 | -1,287,000 | $8.52 |
| 03/31/2021 | Eiger BioPharmaceuticals, Inc. | EIGR | 178,167 | -64,862 | 1,577,000 | -1,410,000 | $8.85 |
| 12/31/2020 | Eiger BioPharmaceuticals, Inc. | EIGR | 243,029 | -36,457 | 2,987,000 | 712,000 | $12.29 |
| 09/30/2020 | Eiger BioPharmaceuticals, Inc. | EIGR | 279,486 | 56,982 | 2,275,000 | 139,000 | $8.14 |
| 06/30/2020 | Eiger BioPharmaceuticals, Inc. | EIGR | 222,504 | 11,007 | 2,136,000 | 698,000 | $9.60 |
| 03/31/2020 | Eiger BioPharmaceuticals, Inc. | EIGR | 211,497 | 112,033 | 1,438,000 | -44,000 | $6.80 |
| 12/31/2019 | Eiger BioPharmaceuticals, Inc. | EIGR | 99,464 | 74,351 | 1,482,000 | 1,225,000 | $14.90 |
| 09/30/2019 | Eiger BioPharmaceuticals, Inc. | EIGR | 25,113 | -52,326 | 257,000 | -564,000 | $10.23 |
| 06/30/2019 | Eiger BioPharmaceuticals, Inc. | EIGR | 77,439 | -2,876 | 821,000 | -302,000 | $10.60 |
| 03/31/2019 | Eiger BioPharmaceuticals, Inc. | EIGR | 80,315 | 39,671 | 1,123,000 | 710,000 | $13.98 |
| 12/31/2018 | Eiger BioPharmaceuticals, Inc. | EIGR | 40,644 | 15,720 | 413,000 | 114,000 | $10.16 |
| 09/30/2018 | Eiger BioPharmaceuticals, Inc. | EIGR | 24,924 | 1,317 | 299,000 | 11,000 | $12.00 |
| 06/30/2018 | Eiger BioPharmaceuticals, Inc. | EIGR | 23,607 | 23,607 | 288,000 | 288,000 | $12.20 |
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