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ZACKS INVESTMENT MANAGEMENT
> VRTX
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,224 | -13,461 | 430,562,000 | -3,810,275,000 | $351,766.34 |
| 12/31/2022 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 14,685 | 1,043 | 4,240,837,000 | 4,236,888,000 | $288,786.99 |
| 09/30/2022 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 13,642 | -15,649 | 3,949,000 | -4,305,000 | $289.47 |
| 06/30/2022 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 29,291 | 376 | 8,254,000 | 709,000 | $281.79 |
| 03/31/2022 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 28,915 | 28,915 | 7,545,000 | 7,545,000 | $260.94 |
| 12/31/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 0 | -1,253 | 0 | -227,000 | |
| 09/30/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,253 | -30,207 | 227,000 | -6,116,000 | $181.17 |
| 06/30/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 31,460 | -8,190 | 6,343,000 | -2,177,000 | $201.62 |
| 03/31/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 39,650 | 10,903 | 8,520,000 | 1,726,000 | $214.88 |
| 12/31/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 28,747 | -8,417 | 6,794,000 | -3,320,000 | $236.34 |
| 09/30/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 37,164 | -7,711 | 10,114,000 | -2,914,000 | $272.15 |
| 06/30/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 44,875 | 2,538 | 13,028,000 | 2,954,000 | $290.32 |
| 03/31/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 42,337 | 10,610 | 10,074,000 | 3,127,000 | $237.95 |
| 12/31/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 31,727 | 1,637 | 6,947,000 | 1,849,000 | $218.96 |
| 09/30/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 30,090 | 30,090 | 5,098,000 | 5,098,000 | $169.43 |
| 12/31/2017 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 0 | -7,937 | 0 | -1,207,000 | |
| 09/30/2017 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 7,937 | 7,937 | 1,207,000 | 1,207,000 | $152.07 |
| 09/30/2016 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 0 | -4,369 | 0 | -455,000 | |
| 03/31/2016 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 0 | -4,464 | 0 | -562,000 | |
| 12/31/2015 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 4,464 | 95 | 562,000 | 107,000 | $125.90 |
| 09/30/2015 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 4,369 | 4,369 | 455,000 | 455,000 | $104.14 |
| 06/30/2015 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 4,378 | 4,378 | 541,000 | 541,000 | $123.57 |
| 09/30/2014 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 0 | -12,327 | 0 | -1,167,000 | |
| 06/30/2014 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 12,327 | 12,327 | 1,167,000 | 1,167,000 | $94.67 |
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