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GEODE CAPITAL MANAGEMENT, LLC
> SPRB
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | SPRUCE BIOSCIENCES, INC. | SPRB | 217,911 | 157,290 | 468,508,000 | 334,536,000 | $2,150.00 |
| 03/31/2023 | SPRUCE BIOSCIENCES, INC. | SPRB | 60,621 | -134 | 133,972,000 | 133,889,000 | $2,209.99 |
| 09/30/2022 | SPRUCE BIOSCIENCES, INC. | SPRB | 60,755 | 0 | 83,000 | -22,000 | $1.37 |
| 06/30/2022 | SPRUCE BIOSCIENCES, INC. | SPRB | 60,755 | -66,273 | 105,000 | -150,000 | $1.73 |
| 03/31/2022 | SPRUCE BIOSCIENCES, INC. | SPRB | 127,028 | -15,441 | 255,000 | -380,000 | $2.01 |
| 12/31/2021 | SPRUCE BIOSCIENCES, INC. | SPRB | 142,469 | 31,052 | 635,000 | -34,000 | $4.46 |
| 09/30/2021 | SPRUCE BIOSCIENCES, INC. | SPRB | 111,417 | -17,129 | 669,000 | -772,000 | $6.00 |
| 06/30/2021 | SPRUCE BIOSCIENCES, INC. | SPRB | 128,546 | 18,999 | 1,441,000 | -377,000 | $11.21 |
| 03/31/2021 | SPRUCE BIOSCIENCES, INC. | SPRB | 109,547 | -7,971 | 1,818,000 | -1,038,000 | $16.60 |
| 12/31/2020 | SPRUCE BIOSCIENCES, INC. | SPRB | 117,518 | 117,518 | 2,856,000 | 2,856,000 | $24.30 |
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