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FMR LLC
> DNLI
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | Denali Therapeutics Inc. | DNLI | 1,079,857 | -13,707 | 31,866,576,000 | 6,670,865,000 | $29,510.00 |
| 03/31/2023 | Denali Therapeutics Inc. | DNLI | 1,093,564 | -1,358,892 | 25,195,711,000 | 25,120,445,000 | $23,040.00 |
| 09/30/2022 | Denali Therapeutics Inc. | DNLI | 2,452,456 | -417,284 | 75,266,000 | -9,190,000 | $30.69 |
| 06/30/2022 | Denali Therapeutics Inc. | DNLI | 2,869,740 | -74,315 | 84,456,000 | -10,255,000 | $29.43 |
| 03/31/2022 | Denali Therapeutics Inc. | DNLI | 2,944,055 | -7,736 | 94,711,000 | -36,939,000 | $32.17 |
| 12/31/2021 | Denali Therapeutics Inc. | DNLI | 2,951,791 | 276,042 | 131,650,000 | -3,341,000 | $44.60 |
| 09/30/2021 | Denali Therapeutics Inc. | DNLI | 2,675,749 | 6,666 | 134,991,000 | -74,371,000 | $50.45 |
| 06/30/2021 | Denali Therapeutics Inc. | DNLI | 2,669,083 | -18,617 | 209,362,000 | 55,895,000 | $78.44 |
| 03/31/2021 | Denali Therapeutics Inc. | DNLI | 2,687,700 | -826,509 | 153,467,000 | -140,883,000 | $57.10 |
| 02/08/2021 | Denali Therapeutics Inc. | DNLI | 6,167,937 | 2,653,728 | 474,684,432 | 180,334,432 | $76.96 |
| 12/31/2020 | Denali Therapeutics Inc. | DNLI | 3,514,209 | -1,357,259 | 294,350,000 | 119,805,000 | $83.76 |
| 09/30/2020 | Denali Therapeutics Inc. | DNLI | 4,871,468 | 57,353 | 174,545,000 | 58,140,000 | $35.83 |
| 06/30/2020 | Denali Therapeutics Inc. | DNLI | 4,814,115 | -411,555 | 116,405,000 | 24,904,000 | $24.18 |
| 03/31/2020 | Denali Therapeutics Inc. | DNLI | 5,225,670 | 1,107,036 | 91,501,000 | 19,755,000 | $17.51 |
| 12/31/2019 | Denali Therapeutics Inc. | DNLI | 4,118,634 | -791,363 | 71,746,000 | -3,475,000 | $17.42 |
| 09/30/2019 | Denali Therapeutics Inc. | DNLI | 4,909,997 | -137,624 | 75,221,000 | -29,567,000 | $15.32 |
| 06/30/2019 | Denali Therapeutics Inc. | DNLI | 5,047,621 | -443,489 | 104,788,000 | -22,715,000 | $20.76 |
| 03/31/2019 | Denali Therapeutics Inc. | DNLI | 5,491,110 | -79,229 | 127,503,000 | 12,419,000 | $23.22 |
| 02/13/2019 | Denali Therapeutics Inc. | DNLI | 7,240,508 | 1,670,169 | 144,665,350 | 29,581,350 | $19.98 |
| 12/31/2018 | Denali Therapeutics Inc. | DNLI | 5,570,339 | -2,140,710 | 115,084,000 | -52,554,000 | $20.66 |
| 09/30/2018 | Denali Therapeutics Inc. | DNLI | 7,711,049 | -325,977 | 167,638,000 | 45,073,000 | $21.74 |
| 06/30/2018 | Denali Therapeutics Inc. | DNLI | 8,037,026 | -1,498,395 | 122,565,000 | -65,187,000 | $15.25 |
| 03/31/2018 | Denali Therapeutics Inc. | DNLI | 9,535,421 | 190,965 | 187,752,000 | 41,604,000 | $19.69 |
| 12/31/2017 | Denali Therapeutics Inc. | DNLI | 9,344,456 | 9,344,456 | 146,148,000 | 146,148,000 | $15.64 |
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