Financial Summary (All financials)
| In millions, except per share items | Dec-31-21 | Dec-31-20 | Dec-31-19 | Dec-31-18 | Dec-31-17 | Dec-31-16 | Dec-31-15 | Dec-31-14 |
| Revenues | 10,981.7 | 13,444.6 | 14,377.9 | 13,452.9 | 12,273.9 | 11,448.8 | 10,763.8 | 9,703.3 |
| Revenue growth | -18.3% | -6.5% | 6.9% | 9.6% | 7.2% | 6.4% | 10.9% | 40.0% |
| Cost of goods sold | 2,991.0 | 2,270.0 | 2,445.3 | 2,563.6 | 2,444.7 | 1,864.3 | -1,240.4 | -1,171.0 |
| Gross profit | 7,990.7 | 11,174.6 | 11,932.6 | 10,889.3 | 9,829.2 | 9,584.5 | 12,004.2 | 10,874.3 |
| Gross margin | 72.8% | 83.1% | 83.0% | 80.9% | 80.1% | 83.7% | 111.5% | 112.1% |
| Selling, general and administrative | 2,674.3 | 2,504.5 | 2,374.7 | 2,106.3 | 1,933.9 | 1,946.6 | 2,113.1 | 2,232.3 |
| Research and development | 2,501.2 | 3,990.9 | 2,280.6 | 2,597.2 | 2,253.6 | 1,973.3 | 2,012.8 | 1,893.4 |
| EBITA | 2,808.0 | 4,538.8 | 6,980.4 | 6,000.8 | 5,529.4 | 5,654.4 | 5,410.0 | 4,455.2 |
| EBITA margin | 25.6% | 33.8% | 48.5% | 44.6% | 45.1% | 49.4% | 50.3% | 45.9% |
| Amortization of intangibles | | | | | | | 382.6 | 489.8 |
| EBIT | 2,808.0 | 4,538.8 | 6,980.4 | 6,000.8 | 5,529.4 | 5,654.4 | 5,027.4 | 3,965.4 |
| EBIT margin | 25.6% | 33.8% | 48.5% | 44.6% | 45.1% | 49.4% | 46.7% | 40.9% |
| Pre-tax income | 1,745.2 | 5,047.5 | 7,125.9 | 5,899.6 | 5,128.8 | 4,933.0 | 4,767.3 | 3,946.6 |
| Income taxes | 52.5 | 992.3 | 1,158.0 | 1,425.6 | 2,458.7 | 1,237.3 | 1,161.6 | 989.9 |
| Tax rate | 3.0% | 19.7% | 16.3% | 24.2% | 47.9% | 25.1% | 24.4% | 25.1% |
| Net income | 1,556.1 | 4,000.6 | 5,888.5 | 4,430.7 | 2,539.1 | 3,702.8 | 3,547.0 | 2,934.8 |
| Net margin | 14.2% | 29.8% | 41.0% | 32.9% | 20.7% | 32.3% | 33.0% | 30.2% |
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| Diluted EPS | $10.40 | $24.80 | $31.42 | $21.58 | $11.92 | $16.92 | $15.34 | $12.37 |
| Shares outstanding (diluted) | 149.6 | 161.3 | 187.4 | 205.3 | 213.0 | 218.8 | 231.2 | 237.2 |
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| EBIT is a non-GAAP figure that excludes all non-recurring expenses: restructuring costs, asset impairments, IPR&D writeoffs, and other unusual charges. |
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