Financial Summary (All financials)
| In millions, except per share items | Dec-31-22 | Dec-31-21 | Dec-31-20 | Dec-31-19 | Dec-31-18 | Dec-31-17 | Dec-31-16 | Dec-31-15 |
| Revenues | 3,659.4 | 3,094.2 | 2,363.6 | 2,161.8 | 1,890.9 | 1,618.7 | 1,488.0 | 1,324.8 |
| Revenue growth | 18.3% | 30.9% | 9.3% | 14.3% | 16.8% | 8.8% | 12.3% | 13.0% |
| Cost of goods sold | 540.5 | 440.8 | 148.9 | 127.9 | 121.5 | 110.2 | 105.4 | 102.5 |
| Gross profit | 3,118.9 | 2,653.5 | 2,214.7 | 2,033.8 | 1,769.4 | 1,508.5 | 1,382.6 | 1,222.3 |
| Gross margin | 85.2% | 85.8% | 93.7% | 94.1% | 93.6% | 93.2% | 92.9% | 92.3% |
| Selling, general and administrative | 1,417.0 | 1,451.7 | 854.2 | 736.9 | 683.5 | 544.2 | 502.9 | 449.1 |
| Research and development | 590.5 | 505.7 | 335.4 | 299.7 | 226.6 | 198.4 | 162.3 | 135.3 |
| EBITA | 1,121.4 | 696.8 | 1,028.0 | 1,001.3 | 861.4 | 766.9 | 693.3 | 637.9 |
| EBITA margin | 30.6% | 22.5% | 43.5% | 46.3% | 45.6% | 47.4% | 46.6% | 48.2% |
| Amortization of intangibles | 599.2 | 525.8 | 259.6 | 354.8 | 201.5 | 152.1 | 102.0 | 98.2 |
| EBIT | 522.2 | 171.0 | 768.4 | 646.4 | 659.9 | 614.9 | 591.3 | 539.7 |
| EBIT margin | 14.3% | 5.5% | 32.5% | 29.9% | 34.9% | 38.0% | 39.7% | 40.7% |
| Pre-tax income | -372.8 | -112.8 | 275.1 | 454.3 | 529.5 | 441.1 | 532.4 | 435.9 |
| Income taxes | -158.6 | 216.1 | 33.5 | -73.2 | 80.2 | -47.7 | 135.2 | 106.4 |
| Tax rate | 42.6% | | 12.2% | | 15.1% | | 25.4% | 24.4% |
| Net income | -224.1 | -329.7 | 238.6 | 523.4 | 447.1 | 487.8 | 396.8 | 329.5 |
| Net margin | -6.1% | -10.7% | 10.1% | 24.2% | 23.6% | 30.1% | 26.7% | 24.9% |
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| Diluted EPS | ($3.58) | ($5.52) | $4.22 | $9.09 | $7.30 | $7.96 | $6.41 | $5.23 |
| Shares outstanding (diluted) | 62.5 | 59.7 | 56.5 | 57.6 | 61.2 | 61.3 | 61.9 | 63.0 |
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| EBIT is a non-GAAP figure that excludes all non-recurring expenses: restructuring costs, asset impairments, IPR&D writeoffs, and other unusual charges. |
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