Type	Name	Date
Credit agreement	DIP Credit Agreement, among Pernix Therapeutics Holdings, Inc., as borrower, the lenders named therein and Cantor Fitzgerald Securities, as administrative agent	02/27/2019
Indenture	Second Supplemental Indenture, by and among Pernix Therapeutics Holdings, Inc., Pernix Holdco 1, LLC, Pernix Holdco 2, LLC, Pernix Holdco 3, LLC and U.S. Bank, National Association as the trustee	07/21/2017
Credit agreement	Credit Agreement, by and among the lenders identified on the signature pages thereof, Cantor Fitzgerald Securities, as agent, Pernix Therapeutics Holdings, Inc., Pernix Therapeutics, LLC, Pernix Sleep, Inc., Cypress Pharmaceuticals, Inc., Gaine, Inc., Respicopea, Inc., Macoven Pharmaceuticals, L.L.C., and Hawthorn Pharmaceuticals, Inc., as borrowers, and the guarantors party thereto	07/21/2017
Credit agreement	Credit Agreement, by and among the lenders identified on the signature pages thereof, Cantor Fitzgerald Securities, as agent, and Pernix Ireland Pain Limited	07/21/2017
Credit agreement	Amendment No. 1 to the Credit Agreement by and among Wells Fargo Bank, National Association, as Administrative Agent, the Lenders that are parties thereto, as Lenders and Pernix Therapeutics Holdings, Inc., Pernix Therapeutics, LLC, Pernix Sleep, Inc., Cypress Pharmaceuticals, Inc., Macoven Pharmaceuticals, Inc., Gaine, Inc., Repicopea Inc. and Macoven Pharmaceuticals, L.L.C., as Borrowers	04/20/2017
Credit agreement	Credit Agreement by and among Wells Fargo Bank, National Association, as Administrative Agent, the Lenders that are parties thereto, as Lenders and Pernix Therapeutics Holdings, Inc., Pernix Therapeutics, LLC, Pernix Sleep, Inc., Cypress Pharmaceuticals, Inc., Macoven Pharmaceuticals, Inc., Gaine, Inc., Repicopea Inc. and Macoven Pharmaceuticals, L.L.C., as Borrowers.dated as of August 21, 2015	08/28/2015
Indenture	First Supplemental Indenture, between Pernix Therapeutics Holdings, Inc. and U.S. Bank National Association, as Trustee	04/24/2015
Indenture	Indenture, between Pernix Therapeutics Holdings, Inc. and Wilmington Trust, National Association, as Trustee	04/24/2015
Indenture	INDENTURE	08/22/2014
Indenture	FIRST SUPPLEMENTAL INDENTURE	08/22/2014
Indenture	SECOND SUPPLEMENTAL INDENTURE	08/22/2014
Credit agreement	AMENDMENT NO. 3 TO AMENDED AND RESTATED CREDIT AGREEMENT	08/22/2014
Credit agreement	Amendment No. 1 to the Amended and Restated Credit Agreement, between Pernix Therapeutics Holdings, Inc. and MidCap Funding IV, LLC, as Agent and as a lender, and the other lenders from time to time parties thereto	02/26/2014
Indenture	Indenture, by and between Pernix Therapeutics Holdings, Inc. and Wilmington Trust, National Association	02/26/2014
Credit agreement	Amended and Restated Credit Agreement by and among Pernix Therapeutics Holdings, Inc., together with its subsidiaries, MidCap Financial, LLC, as Administrative Agent and as lender, and additional lenders from time to time party thereto	05/13/2013
Credit agreement	Credit and Guaranty Agreement among the Company and its subsidiaries, on the one hand, and Midcap Funding V, LLC, as Administrative Agent, as a Lender and as Co-Bookrunner and Sole Lead Arranger, Business Development Corporation of America, as Co-Bookrunner, and additional lenders from time to time party thereto, on the other hand	01/04/2013

Type	Name	Date
Employment agreement	EMPLOYMENT AGREEMENT	02/06/2018
Employment agreement	Employment Agreement, by and between Pernix Therapeutics Holdings, Inc. and John A. Sedor	11/07/2016
Employment agreement	Employment Agreement, by and between Pernix Therapeutics Holdings, Inc. and Graham G. Miao, Ph.D	11/07/2016
Employment agreement	Employment Agreement by and between Pernix Therapeutics Holdings, Inc. and Douglas Drysdale	02/07/2014
Equity incentive plans	2009 Stock Incentive Plan	03/15/2010

Type	Name	Date
Acquisition / asset purchase agreement	Asset Purchase Agreement, by and among Pernix Therapeutics Holdings, Inc., the other Sellers party thereto, and Phoenix Top Holdings LLC	02/19/2019