| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 06/30/2023 | Cyclacel Pharmaceuticals, Inc. | CYCC | Grant | Common Stock | 21.2k | $0.00 | $0 | | 06/30/2023 |
| 06/30/2023 | Cyclacel Pharmaceuticals, Inc. | CYCC | Grant | Stock Option (right to buy) | 42.4k | $0.59 | $25k | | 06/30/2023 |
| 07/14/2021 | PROTHENA CORP PUBLIC LTD CO | PRTA | Sale | Ordinary Shares, par value $0.01 per share | 9.1k | $55.31 | $503.8k | | 07/14/2021 |
| 07/14/2021 | PROTHENA CORP PUBLIC LTD CO | PRTA | Sale | Ordinary Shares, par value $0.01 per share | 2k | $56.13 | $112.3k | | 07/14/2021 |
| 07/14/2021 | PROTHENA CORP PUBLIC LTD CO | PRTA | Exercise | Stock Option (Right to Buy) | 11.1k | $11.33 | $125.9k | | 07/14/2021 |
| 07/12/2021 | PROTHENA CORP PUBLIC LTD CO | PRTA | Exercise | Stock Option (Right to Buy) | 6.4k | $11.33 | $72.4k | | 07/12/2021 |
| 07/12/2021 | PROTHENA CORP PUBLIC LTD CO | PRTA | Exercise | Stock Option (Right to Buy) | 17.5k | $9.23 | $161.5k | | 07/12/2021 |
| 07/12/2021 | PROTHENA CORP PUBLIC LTD CO | PRTA | Sale | Ordinary Shares, par value $0.01 per share | 300 | $59.45 | $17.8k | | 07/12/2021 |
| 07/12/2021 | PROTHENA CORP PUBLIC LTD CO | PRTA | Sale | Ordinary Shares, par value $0.01 per share | 800 | $58.66 | $46.9k | | 07/12/2021 |
| 07/12/2021 | PROTHENA CORP PUBLIC LTD CO | PRTA | Sale | Ordinary Shares, par value $0.01 per share | 700 | $57.85 | $40.5k | | 07/12/2021 |
| 07/12/2021 | PROTHENA CORP PUBLIC LTD CO | PRTA | Sale | Ordinary Shares, par value $0.01 per share | 2.1k | $56.56 | $118.8k | | 07/12/2021 |
| 07/12/2021 | PROTHENA CORP PUBLIC LTD CO | PRTA | Sale | Ordinary Shares, par value $0.01 per share | 2.3k | $55.26 | $127.9k | | 07/12/2021 |
| 07/12/2021 | PROTHENA CORP PUBLIC LTD CO | PRTA | Sale | Ordinary Shares, par value $0.01 per share | 177 | $61.25 | $10.8k | | 07/12/2021 |
| 07/12/2021 | PROTHENA CORP PUBLIC LTD CO | PRTA | Sale | Ordinary Shares, par value $0.01 per share | 600 | $59.25 | $35.5k | | 07/12/2021 |
| 07/12/2021 | PROTHENA CORP PUBLIC LTD CO | PRTA | Sale | Ordinary Shares, par value $0.01 per share | 500 | $58.21 | $29.1k | | 07/12/2021 |
| 07/12/2021 | PROTHENA CORP PUBLIC LTD CO | PRTA | Sale | Ordinary Shares, par value $0.01 per share | 1.6k | $56.88 | $92.9k | | 07/12/2021 |
| 07/12/2021 | PROTHENA CORP PUBLIC LTD CO | PRTA | Sale | Ordinary Shares, par value $0.01 per share | 2.5k | $55.95 | $138.5k | | 07/12/2021 |
| 07/12/2021 | PROTHENA CORP PUBLIC LTD CO | PRTA | Sale | Ordinary Shares, par value $0.01 per share | 5.9k | $54.55 | $321.1k | | 07/12/2021 |
| 07/12/2021 | PROTHENA CORP PUBLIC LTD CO | PRTA | Sale | Ordinary Shares, par value $0.01 per share | 6.2k | $53.84 | $335.3k | | 07/12/2021 |
| 07/12/2021 | PROTHENA CORP PUBLIC LTD CO | PRTA | Sale | Ordinary Shares, par value $0.01 per share | 600 | $59.25 | $35.5k | | 07/12/2021 |
| 07/12/2021 | PROTHENA CORP PUBLIC LTD CO | PRTA | Sale | Ordinary Shares, par value $0.01 per share | 177 | $61.25 | $10.8k | | 07/12/2021 |
| 07/12/2021 | PROTHENA CORP PUBLIC LTD CO | PRTA | Sale | Ordinary Shares, par value $0.01 per share | 2.3k | $55.26 | $127.9k | | 07/12/2021 |
| 07/12/2021 | PROTHENA CORP PUBLIC LTD CO | PRTA | Sale | Ordinary Shares, par value $0.01 per share | 2.1k | $56.56 | $118.8k | | 07/12/2021 |
| 07/12/2021 | PROTHENA CORP PUBLIC LTD CO | PRTA | Sale | Ordinary Shares, par value $0.01 per share | 700 | $57.85 | $40.5k | | 07/12/2021 |
| 07/12/2021 | PROTHENA CORP PUBLIC LTD CO | PRTA | Sale | Ordinary Shares, par value $0.01 per share | 800 | $58.66 | $46.9k | | 07/12/2021 |
| 07/12/2021 | PROTHENA CORP PUBLIC LTD CO | PRTA | Sale | Ordinary Shares, par value $0.01 per share | 300 | $59.45 | $17.8k | | 07/12/2021 |
| 07/12/2021 | PROTHENA CORP PUBLIC LTD CO | PRTA | Exercise | Stock Option (Right to Buy) | 17.5k | $9.23 | $161.5k | | 07/12/2021 |
| 07/12/2021 | PROTHENA CORP PUBLIC LTD CO | PRTA | Exercise | Stock Option (Right to Buy) | 6.4k | $11.33 | $72.4k | | 07/12/2021 |
| 07/12/2021 | PROTHENA CORP PUBLIC LTD CO | PRTA | Sale | Ordinary Shares, par value $0.01 per share | 6.2k | $53.84 | $335.3k | | 07/12/2021 |
| 07/12/2021 | PROTHENA CORP PUBLIC LTD CO | PRTA | Sale | Ordinary Shares, par value $0.01 per share | 5.9k | $54.55 | $321.1k | | 07/12/2021 |
| 07/12/2021 | PROTHENA CORP PUBLIC LTD CO | PRTA | Sale | Ordinary Shares, par value $0.01 per share | 2.5k | $55.95 | $138.5k | | 07/12/2021 |
| 07/12/2021 | PROTHENA CORP PUBLIC LTD CO | PRTA | Sale | Ordinary Shares, par value $0.01 per share | 1.6k | $56.88 | $92.9k | | 07/12/2021 |
| 07/12/2021 | PROTHENA CORP PUBLIC LTD CO | PRTA | Sale | Ordinary Shares, par value $0.01 per share | 500 | $58.21 | $29.1k | | 07/12/2021 |
| 06/25/2021 | PROTHENA CORP PUBLIC LTD CO | PRTA | Sale | Ordinary Shares, par value $0.01 per share | 10.3k | $47.57 | $488.2k | | 06/25/2021 |
| 06/25/2021 | PROTHENA CORP PUBLIC LTD CO | PRTA | Sale | Ordinary Shares, par value $0.01 per share | 1.7k | $48.73 | $84.6k | | 06/25/2021 |
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