| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 02/08/2023 | Zynerba Pharmaceuticals, Inc. | ZYNE | Payment of Exercise | Common Stock | 6.5k | $0.60 | $3.9k | | 02/07/2023 |
| 02/07/2023 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Common Stock | 22.5k | $0.00 | $0 | | 02/07/2023 |
| 01/24/2023 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Common Stock | 170k | $0.00 | $0 | | 01/23/2023 |
| 01/23/2023 | Zynerba Pharmaceuticals, Inc. | ZYNE | Sale | Common Stock | 17.8k | $0.60 | $10.6k | | 01/23/2023 |
| 07/19/2022 | Zynerba Pharmaceuticals, Inc. | ZYNE | Sale | Common Stock | 6k | $1.10 | $6.6k | | 07/18/2022 |
| 07/18/2022 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Common Stock | 20.8k | $0.00 | $0 | | 07/18/2022 |
| 01/26/2022 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Stock Option (right to buy) | 125k | $2.41 | $301.2k | | 01/26/2022 |
| 01/26/2022 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Common Stock | 85k | $0.00 | $0 | | 01/26/2022 |
| 01/21/2021 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Common Stock | 52k | $0.00 | $0 | | 01/21/2021 |
| 01/21/2021 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Stock Option (right to buy) | 78k | $3.58 | $279.2k | | 01/21/2021 |
| 01/30/2020 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Stock Option (right to buy) | 85k | $5.05 | $429.2k | | 01/30/2020 |
| 01/24/2019 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Stock Option (right to buy) | 88.1k | $3.65 | $321.6k | | 01/24/2019 |
| 08/06/2018 | Zynerba Pharmaceuticals, Inc. | ZYNE | Purchase | Common Stock | 8.5k | $5.97 | $50.8k | | 08/06/2018 |
| 01/11/2018 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Stock Option (right to buy) | 67.5k | $11.71 | $790.4k | | 01/11/2018 |
| 05/12/2017 | Zynerba Pharmaceuticals, Inc. | ZYNE | Purchase | Common Stock | 5.2k | $19.82 | $103.1k | | 05/12/2017 |
| 01/25/2017 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Stock Option (right to buy) | 31.4k | $18.22 | $571.2k | | 01/25/2017 |
| 12/07/2016 | Zynerba Pharmaceuticals, Inc. | ZYNE | Purchase | Common Stock | 4k | $14.03 | $56.1k | | 12/06/2016 |
| 12/06/2016 | Zynerba Pharmaceuticals, Inc. | ZYNE | Purchase | Common Stock | 3k | $14.15 | $42.4k | | 12/06/2016 |
| 09/13/2016 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Stock Option (right to buy) | 150k | $10.23 | $1.5M | | 09/13/2016 |
| 06/02/2016 | ANTARES PHARMA, INC. | ATRS | Grant | Common Stock | 121k | $1.12 | $135.6k | | 06/02/2016 |
| 06/02/2016 | ANTARES PHARMA, INC. | ATRS | Grant | Stock option (right to buy) | 257.9k | $1.12 | $288.8k | | 06/02/2016 |
| 02/07/2013 | AUXILIUM PHARMACEUTICALS INC | AUXL | Grant | Nonqualified Stock Option (Right to Buy) | 37.5k | $18.30 | $686.2k | | 02/07/2013 |
| 02/07/2013 | AUXILIUM PHARMACEUTICALS INC | AUXL | Payment of Exercise | Common Stock | 482 | $18.30 | $8.8k | | 02/07/2013 |
| 02/07/2013 | AUXILIUM PHARMACEUTICALS INC | AUXL | Grant | Common Stock | 15.2k | $0.00 | $0 | | 02/07/2013 |
| 02/07/2013 | AUXILIUM PHARMACEUTICALS INC | AUXL | Grant | Common Stock | 3.9k | $0.00 | $0 | | 02/07/2013 |
| 06/21/2012 | AUXILIUM PHARMACEUTICALS INC | AUXL | Grant | Common Stock | 750 | $0.00 | $0 | | 06/21/2012 |
| 02/14/2012 | AUXILIUM PHARMACEUTICALS INC | AUXL | Grant | Nonqualified Stock Options (Right to Buy) | 57k | $19.51 | $1.1M | | 02/14/2012 |
| 02/17/2011 | AUXILIUM PHARMACEUTICALS INC | AUXL | Grant | Nonqualified Stock Option (Right to Buy) | 40k | $22.04 | $881.6k | | 02/17/2011 |