ORTH ANDREW C. [Rocket]

Date	Name	Symbol	Type	Security	Shares	Price	Value	Reported
06/09/2023	Krystal Biotech, Inc.	KRYS	Sale	Common Stock	5.3k	$128.10	$674k	06/09/2023
06/09/2023	Krystal Biotech, Inc.	KRYS	Sale	Common Stock	6.9k	$128.94	$890.5k	06/09/2023
06/09/2023	Krystal Biotech, Inc.	KRYS	Sale	Common Stock	333	$129.70	$43.2k	06/09/2023
06/09/2023	Krystal Biotech, Inc.	KRYS	Exercise	Stock Option (Right to Buy)	12.5k	$63.55	$794.4k	06/09/2023
02/28/2023	Krystal Biotech, Inc.	KRYS	Grant	Stock Option (Right to Buy)	20k	$81.91	$1.6M	02/28/2023
02/28/2023	Krystal Biotech, Inc.	KRYS	Grant	Performance Stock Units	10k	$0.00	$0	02/28/2023
02/28/2022	Krystal Biotech, Inc.	KRYS	Grant	Stock Option (Right to Buy)	50k	$63.55	$3.2M	02/28/2022
05/31/2021	Krystal Biotech, Inc.	KRYS	Grant	Stock Option (Right to Buy)	205k	$65.24	$13.4M	05/31/2021