| Date | Name | Title | Type | Security | Shares | Price | Value | Ownership | Reported |
| 08/15/2023 | DAMATO NICOLE | CHIEF LEGAL OFFICER | Payment of Exercise | Common Stock, $0.001 par value | 9.7k | $5.60 | $54.2k | | 08/15/2023 |
| 08/15/2023 | Feifer Richard | CHIEF MEDICAL OFFICER | Payment of Exercise | Common Stock, $0.001 par value | 9.7k | $5.60 | $54.5k | | 08/15/2023 |
| 08/14/2023 | Sparks Teresa | Director | Grant | Common Stock, $0.001 par value | 17.4k | $0.00 | $0 | | 08/14/2023 |
| 07/13/2023 | DAMATO NICOLE | CHIEF LEGAL OFFICER | Sale | Common Stock, $0.001 par value | 3.4k | $7.07 | $24.4k | | 07/13/2023 |
| 07/12/2023 | DAMATO NICOLE | CHIEF LEGAL OFFICER | Sale | Common Stock, $0.001 par value | 411 | $7.08 | $2.9k | | 07/11/2023 |
| 07/11/2023 | DAMATO NICOLE | CHIEF LEGAL OFFICER | Sale | Common Stock, $0.001 par value | 892 | $7.06 | $6.3k | | 07/11/2023 |
| 07/10/2023 | DAMATO NICOLE | CHIEF LEGAL OFFICER | Sale | Common Stock, $0.001 par value | 6.4k | $7.10 | $45.6k | | 07/06/2023 |
| 07/06/2023 | DAMATO NICOLE | CHIEF LEGAL OFFICER | Sale | Common Stock, $0.001 par value | 139 | $7.01 | $974.4 | | 07/06/2023 |
| 07/05/2023 | DAMATO NICOLE | CHIEF LEGAL OFFICER | Sale | Common Stock, $0.001 par value | 4.2k | $7.28 | $30.4k | | 07/02/2023 |
| 07/03/2023 | DAMATO NICOLE | CHIEF LEGAL OFFICER | Sale | Common Stock, $0.001 par value | 2.1k | $7.26 | $15.3k | | 07/02/2023 |
| 07/02/2023 | DAMATO NICOLE | CHIEF LEGAL OFFICER | Payment of Exercise | Common Stock, $0.001 par value | 20.2k | $7.50 | $151.6k | | 07/02/2023 |
| 12/01/2022 | BLAIR PATRICK T | President and CEO | Payment of Exercise | Common Stock, $0.001 par value | 20.1k | $7.20 | $144.4k | | 12/01/2022 |
| 09/15/2022 | Scully Thomas | Director | Purchase | Common Stock, $0.001 par value | 100k | $5.10 | $509.8k | | 09/15/2022 |
| 08/15/2022 | Feifer Richard | CHIEF MEDICAL OFFICER | Grant | Common Stock, $0.001 par value | 92.6k | $0.00 | $0 | | 08/15/2022 |
| 08/15/2022 | DAMATO NICOLE | CHIEF LEGAL OFFICER | Grant | Common Stock, $0.001 par value | 92.6k | $0.00 | $0 | | 08/15/2022 |
| 07/02/2022 | DAMATO NICOLE | CHIEF LEGAL OFFICER | Payment of Exercise | Common Stock, $0.001 par value | 10.7k | $4.45 | $47.6k | | 07/02/2022 |
| 06/30/2022 | CARLSON JAMES G | Director | Grant | Common Stock, $0.001 par value | 28.5k | $0.00 | $0 | | 06/30/2022 |
| 03/16/2022 | DAMATO NICOLE | CHIEF LEGAL OFFICER | Grant | Common Stock, $0.001 par value | 38.8k | $0.00 | $0 | | 02/04/2022 |
| 02/04/2022 | DAMATO NICOLE | CHIEF LEGAL OFFICER | Grant | Common Stock, $0.001 par value | 33.2k | $0.00 | $0 | | 02/04/2022 |
| 12/01/2021 | BLAIR PATRICK T | President and CEO | Grant | Nonqualified Stock Options (Right to Buy) | 1.3M | $7.89 | $10.5M | | 12/01/2021 |
| 12/01/2021 | BLAIR PATRICK T | President and CEO | Grant | Common Stock, $0.001 Par value | 443.6k | $0.00 | $0 | | 12/01/2021 |
| 03/15/2021 | DOERR ROBIN | Chief Sales and MKTG Officer | Purchase | Common Stock, $0.001 Par value | 1.9k | $25.74 | $48.3k | | 03/15/2021 |
| 03/12/2021 | HEWITT MAUREEN | CEO, President and Director | Purchase | Common Stock, $0.001 Par value | 9.4k | $26.62 | $248.9k | Trust | 03/12/2021 |
| 03/12/2021 | GUTIERREZ BARBARA | CFO | Purchase | Common Stock, $0.001 Par value | 2k | $26.43 | $52.9k | | 03/12/2021 |
| 03/08/2021 | Kennedy Edward Moore Jr. | Director | Purchase | Common Stock, $0.001 par value | 23k | $21.00 | $483k | | 03/08/2021 |