| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 06/07/2023 | Vigil Neuroscience, Inc. | | Grant | Stock Option Grant (Right to Buy) | 13.9k | $10.00 | $139.3k | | 06/07/2023 |
| 06/09/2022 | Vigil Neuroscience, Inc. | | Grant | Stock Option Grant (Right to Buy) | 12.2k | $3.10 | $37.7k | | 06/09/2022 |
| 05/26/2022 | Praxis Precision Medicines, Inc. | PRAX | Grant | Stock Option (Right to Buy) | 22.8k | $8.38 | $190.7k | | 05/26/2022 |
| 01/11/2022 | Vigil Neuroscience, Inc. | | Conversion | Common Stock | 3.3M | $0.00 | $0 | By Vida Ventures III, L.P. | 01/11/2022 |
| 01/11/2022 | Vigil Neuroscience, Inc. | | Conversion | Common Stock | 7.7k | $0.00 | $0 | By Vida Ventures III-A, L.P. | 01/11/2022 |
| 01/11/2022 | Vigil Neuroscience, Inc. | | Purchase | Common Stock | 1.7M | $14.00 | $23.4M | By Vida Ventures III, L.P. | 01/11/2022 |
| 01/11/2022 | Vigil Neuroscience, Inc. | | Purchase | Common Stock | 3.9k | $14.00 | $53.9k | By Vida Ventures III-A, L.P. | 01/11/2022 |
| 01/11/2022 | Vigil Neuroscience, Inc. | | Conversion | Series B Preferred Stock | 9.2M | $0.00 | $0 | By Vida Ventures III, L.P. | 01/11/2022 |
| 01/11/2022 | Vigil Neuroscience, Inc. | | Conversion | Series B Preferred Stock | 21.3k | $0.00 | $0 | By Vida Ventures III-A, L.P. | 01/11/2022 |
| 06/08/2021 | Praxis Precision Medicines, Inc. | PRAX | Grant | Stock Option (Right to Buy) | 22.3k | $20.42 | $456.2k | | 06/08/2021 |
| 10/20/2020 | Praxis Precision Medicines, Inc. | PRAX | Conversion | Common Stock | 2.7M | $0.00 | $0 | See Footnote | 10/20/2020 |
| 10/20/2020 | Praxis Precision Medicines, Inc. | PRAX | Purchase | Common Stock | 250k | $19.00 | $4.8M | See Footnote | 10/20/2020 |
| 10/20/2020 | Praxis Precision Medicines, Inc. | PRAX | Conversion | Series B Preferred Stock | 4.2M | $0.00 | $0 | See Footnote | 10/20/2020 |
| 10/20/2020 | Praxis Precision Medicines, Inc. | PRAX | Conversion | Series B-1 Preferred Stock | 551.8k | $0.00 | $0 | See Footnote | 10/20/2020 |
| 10/20/2020 | Praxis Precision Medicines, Inc. | PRAX | Conversion | Series C Preferred Stock | 171.4k | $0.00 | $0 | See Footnote | 10/20/2020 |
| 10/20/2020 | Praxis Precision Medicines, Inc. | PRAX | Conversion | Series C-1 Preferred Stock | 881.8k | $0.00 | $0 | See Footnote | 10/20/2020 |
| 10/20/2020 | Praxis Precision Medicines, Inc. | PRAX | Conversion | Common Stock | 2.7M | $0.00 | $0 | See Footnote | 10/20/2020 |
| 10/20/2020 | Praxis Precision Medicines, Inc. | PRAX | Conversion | Series B Preferred Stock | 4.2M | $0.00 | $0 | See Footnote | 10/20/2020 |
| 10/20/2020 | Praxis Precision Medicines, Inc. | PRAX | Conversion | Series B -1 Preferred Stock | 551.8k | $0.00 | $0 | See Footnote | 10/20/2020 |
| 10/20/2020 | Praxis Precision Medicines, Inc. | PRAX | Conversion | Series C Preferred Stock | 171.4k | $0.00 | $0 | See Footnote | 10/20/2020 |
| 10/20/2020 | Praxis Precision Medicines, Inc. | PRAX | Conversion | Series C -1 Preferred Stock | 881.8k | $0.00 | $0 | See Footnote | 10/20/2020 |