| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 12/02/2020 | BIOSPECIFICS TECHNOLOGIES CORP | BSTC | Disposition | Common Stock, $0.001 par value | 1.7k | $0.00 | $0 | | 12/02/2020 |
| 12/02/2020 | BIOSPECIFICS TECHNOLOGIES CORP | BSTC | Disposition | Common Stock, $0.001 par value | 16.9k | $0.00 | $0 | | 12/02/2020 |
| 07/15/2020 | BIOSPECIFICS TECHNOLOGIES CORP | BSTC | Grant | Common Stock, $0.001 par value | 1.7k | $0.00 | $0 | | 07/15/2020 |
| 07/01/2019 | BIOSPECIFICS TECHNOLOGIES CORP | BSTC | Grant | Common Stock, $0.001 par value | 1.9k | $0.00 | $0 | | 07/01/2019 |
| 05/15/2019 | BIOSPECIFICS TECHNOLOGIES CORP | BSTC | Sale | Common Stock, $0.001 par value | 5k | $65.83 | $329.2k | | 05/15/2019 |
| 09/07/2018 | BIOSPECIFICS TECHNOLOGIES CORP | BSTC | Sale | Common Stock, $0.001 par value | 1000 | $57.64 | $57.6k | | 09/07/2018 |
| 08/29/2018 | BIOSPECIFICS TECHNOLOGIES CORP | BSTC | Sale | Common Stock, $0.001 par value | 4k | $49.79 | $199.2k | | 08/27/2018 |
| 08/29/2018 | BIOSPECIFICS TECHNOLOGIES CORP | BSTC | Sale | Common Stock, $0.001 par value | 5k | $49.79 | $249k | | 08/27/2018 |
| 08/28/2018 | BIOSPECIFICS TECHNOLOGIES CORP | BSTC | Sale | Common Stock, $0.001 par value | 5k | $48.88 | $244.4k | | 08/27/2018 |
| 08/28/2018 | BIOSPECIFICS TECHNOLOGIES CORP | BSTC | Sale | Common Stock, $0.001 par value | 5k | $48.88 | $244.4k | | 08/27/2018 |
| 08/27/2018 | BIOSPECIFICS TECHNOLOGIES CORP | BSTC | Sale | Common Stock, $0.001 par value | 10k | $50.11 | $501.1k | | 08/27/2018 |
| 08/27/2018 | BIOSPECIFICS TECHNOLOGIES CORP | BSTC | Sale | Common Stock, $0.001 par value | 10k | $50.11 | $501.1k | | 08/27/2018 |
| 08/24/2018 | BIOSPECIFICS TECHNOLOGIES CORP | BSTC | Sale | Common Stock, $0.001 par value | 6.4k | $51.09 | $327k | | 08/23/2018 |
| 08/24/2018 | BIOSPECIFICS TECHNOLOGIES CORP | BSTC | Sale | Common Stock, $0.001 par value | 6.4k | $51.09 | $327k | | 08/23/2018 |
| 08/23/2018 | BIOSPECIFICS TECHNOLOGIES CORP | BSTC | Sale | Common Stock, $0.001 par value | 5.4k | $51.27 | $278.2k | | 08/23/2018 |
| 08/23/2018 | BIOSPECIFICS TECHNOLOGIES CORP | BSTC | Sale | Common Stock, $0.001 par value | 5.4k | $51.27 | $278.2k | | 08/23/2018 |
| 07/20/2015 | BIOSPECIFICS TECHNOLOGIES CORP | BSTC | Sale | Common Stock, $0.001 par value | 8.7k | $53.00 | $460.7k | | 07/20/2015 |
| 07/20/2015 | BIOSPECIFICS TECHNOLOGIES CORP | BSTC | Exercise | Stock Option (Right to Buy) | 8.7k | $13.60 | $118.2k | | 07/20/2015 |
| 06/23/2015 | BIOSPECIFICS TECHNOLOGIES CORP | BSTC | Sale | Common Stock, $0.001 par value | 6.3k | $53.59 | $338k | | 06/23/2015 |
| 06/23/2015 | BIOSPECIFICS TECHNOLOGIES CORP | BSTC | Sale | Common Stock, $0.001 par value | 15k | $51.84 | $777.6k | | 06/23/2015 |
| 06/23/2015 | BIOSPECIFICS TECHNOLOGIES CORP | BSTC | Sale | Common Stock, $0.001 par value | 15k | $50.95 | $764.3k | | 06/23/2015 |
| 06/23/2015 | BIOSPECIFICS TECHNOLOGIES CORP | BSTC | Exercise | Stock Option (Right to Buy) | 6.3k | $13.60 | $85.8k | | 06/23/2015 |
| 06/23/2015 | BIOSPECIFICS TECHNOLOGIES CORP | BSTC | Exercise | Stock Option (Right to Buy) | 15k | $26.43 | $396.4k | | 06/23/2015 |
| 06/23/2015 | BIOSPECIFICS TECHNOLOGIES CORP | BSTC | Exercise | Stock Option (Right to Buy) | 15k | $20.00 | $300k | | 06/23/2015 |
| 05/29/2015 | BIOSPECIFICS TECHNOLOGIES CORP | BSTC | Sale | Common Stock, $0.001 par value | 11k | $46.75 | $514.2k | | 05/29/2015 |
| 05/29/2015 | BIOSPECIFICS TECHNOLOGIES CORP | BSTC | Sale | Common Stock, $0.001 par value | 4k | $46.79 | $187.2k | | 05/29/2015 |
| 05/27/2015 | BIOSPECIFICS TECHNOLOGIES CORP | BSTC | Sale | Common Stock, $0.001 par value | 24k | $42.00 | $1M | | 05/27/2015 |
| 05/27/2015 | BIOSPECIFICS TECHNOLOGIES CORP | BSTC | Exercise | Stock Option (Right to Buy) | 24k | $4.00 | $96k | | 05/27/2015 |
| 01/26/2015 | BIOSPECIFICS TECHNOLOGIES CORP | BSTC | Exercise | Stock Option (Right to Buy) | 5.9k | $1.00 | $5.9k | | 01/23/2015 |
| 01/23/2015 | BIOSPECIFICS TECHNOLOGIES CORP | BSTC | Sale | Common Stock, $0.001 par value | 5.9k | $41.00 | $241.4k | | 01/23/2015 |
| 01/20/2015 | BIOSPECIFICS TECHNOLOGIES CORP | BSTC | Exercise | Stock Option (Right to Buy) | 4.1k | $1.00 | $4.1k | | 01/16/2015 |
| 01/16/2015 | BIOSPECIFICS TECHNOLOGIES CORP | BSTC | Sale | Common Stock, $0.001 par value | 4.1k | $41.00 | $168.6k | | 01/16/2015 |
| 11/24/2014 | BIOSPECIFICS TECHNOLOGIES CORP | BSTC | Sale | Common Stock, $0.001 par value | 100 | $40.00 | $4k | | 11/24/2014 |
| 11/24/2014 | BIOSPECIFICS TECHNOLOGIES CORP | BSTC | Sale | Common Stock, $0.001 par value | 7.5k | $39.50 | $296.2k | | 11/24/2014 |
| 11/12/2014 | BIOSPECIFICS TECHNOLOGIES CORP | BSTC | Exercise | Stock Option (Right to Buy) | 15k | $5.15 | $77.2k | | 11/12/2014 |
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