| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 01/03/2023 | Oyster Point Pharma, Inc. | OYST | Disposition | Stock Option (Right to Buy) | 161.3k | $11.51 | $1.9M | | 01/29/2022 |
| 01/03/2023 | Oyster Point Pharma, Inc. | OYST | Disposition | Performance Stock Units | 300k | $0.00 | $0 | | 01/29/2022 |
| 01/03/2023 | Oyster Point Pharma, Inc. | OYST | Disposition | Common Stock | 20.2k | $0.00 | $0 | | 01/29/2022 |
| 01/03/2023 | Oyster Point Pharma, Inc. | OYST | Other | Common Stock | 56.3k | $0.00 | $0 | | 01/29/2022 |
| 01/03/2023 | Oyster Point Pharma, Inc. | OYST | Disposition | Stock Option (Right to Buy) | 72.6k | $32.65 | $2.4M | | 01/29/2022 |
| 01/03/2023 | Oyster Point Pharma, Inc. | OYST | Disposition | Stock Option (Right to Buy) | 50.5k | $18.77 | $947.9k | | 01/29/2022 |
| 01/03/2023 | Oyster Point Pharma, Inc. | OYST | Disposition | Stock Option (Right to Buy) | 87.9k | $16.00 | $1.4M | | 01/29/2022 |
| 01/03/2023 | Oyster Point Pharma, Inc. | OYST | Disposition | Stock Option (Right to Buy) | 45k | $13.78 | $620.1k | | 01/29/2022 |
| 12/01/2022 | Oyster Point Pharma, Inc. | OYST | Payment of Exercise | Common Stock | 3.3k | $11.20 | $36.5k | | 12/01/2022 |
| 07/06/2022 | Oyster Point Pharma, Inc. | OYST | Grant | Performance Stock Units | 300k | $0.00 | $0 | | 07/06/2022 |
| 01/29/2022 | Oyster Point Pharma, Inc. | OYST | Payment of Exercise | Common Stock | 938 | $11.70 | $11k | | 01/29/2022 |
| 01/09/2022 | Oyster Point Pharma, Inc. | OYST | Grant | Common Stock | 19.5k | $0.00 | $0 | | 01/09/2022 |
| 01/09/2022 | Oyster Point Pharma, Inc. | OYST | Grant | Employee Stock Option (Right to Buy) | 87.9k | $16.00 | $1.4M | | 01/09/2022 |
| 11/01/2021 | Oyster Point Pharma, Inc. | OYST | Exercise | Employee Stock Option (Right to Buy) | 8.6k | $11.51 | $98.9k | | 11/01/2021 |
| 09/02/2021 | Oyster Point Pharma, Inc. | OYST | Exercise | Employee Stock Option (Right to Buy) | 7.5k | $11.51 | $86.3k | | 09/02/2021 |
| 08/26/2021 | Oyster Point Pharma, Inc. | OYST | Grant | Employee Stock Option (Right to Buy) | 45k | $13.78 | $620.1k | | 08/26/2021 |
| 07/28/2021 | Oyster Point Pharma, Inc. | OYST | Exercise | Employee Stock Option (Right to Buy) | 7.5k | $11.51 | $86.3k | | 07/28/2021 |
| 02/24/2021 | Oyster Point Pharma, Inc. | OYST | Exercise | Employee Stock Option (Right to Buy) | 9.1k | $11.51 | $104.8k | | 02/24/2021 |
| 01/29/2021 | Oyster Point Pharma, Inc. | OYST | Grant | Common Stock | 11.2k | $0.00 | $0 | | 01/29/2021 |
| 01/29/2021 | Oyster Point Pharma, Inc. | OYST | Grant | Employee Stock Option (Right to Buy) | 50.5k | $18.77 | $947.9k | | 01/29/2021 |
| 09/25/2020 | Oyster Point Pharma, Inc. | OYST | Exercise | Employee Stock Option (Right to Buy) | 4k | $11.51 | $46k | | 09/25/2020 |
| 08/11/2020 | Oyster Point Pharma, Inc. | OYST | Exercise | Employee Stock Option (Right to Buy) | 4k | $11.51 | $46k | | 08/11/2020 |
| 08/11/2020 | Oyster Point Pharma, Inc. | OYST | Exercise | Common Stock | 4k | $11.51 | $46k | | 08/11/2020 |
| 02/03/2020 | Oyster Point Pharma, Inc. | OYST | Grant | Employee Stock Option (Right to Buy) | 72.6k | $32.65 | $2.4M | | 02/03/2020 |
| 11/04/2019 | Oyster Point Pharma, Inc. | OYST | Purchase | Common Stock, par value $0.001 per share | 6.3k | $16.00 | $100.8k | | 11/04/2019 |