| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 08/09/2022 | Nurix Therapeutics, Inc. | NRIX | Grant | Employee Stock Option (right to buy) | 400k | $18.50 | $7.4M | | 08/09/2022 |
| 01/20/2022 | Nurix Therapeutics, Inc. | NRIX | Grant | Employee Stock Option (right to buy) | 300k | $18.89 | $5.7M | | 01/20/2022 |
| 02/11/2021 | Nurix Therapeutics, Inc. | NRIX | Grant | Employee Stock Option (right to buy) | 150k | $38.97 | $5.8M | | 02/11/2021 |
| 10/21/2020 | Nurix Therapeutics, Inc. | NRIX | Grant | Stock Option (right to buy) | 804.2k | $26.91 | $21.6M | | 10/21/2020 |
| 02/28/2014 | LEXICON PHARMACEUTICALS, INC. | LXRX | Exercise | Restricted Stock Units (Phantom Stock) | 35k | $0.00 | $0 | | 02/28/2014 |
| 02/28/2014 | LEXICON PHARMACEUTICALS, INC. | LXRX | Exercise | Restricted Stock Units (Phantom Stock) | 37k | $0.00 | $0 | | 02/28/2014 |
| 02/28/2014 | LEXICON PHARMACEUTICALS, INC. | LXRX | Exercise | Restricted Stock Units (Phantom Stock) | 36.2k | $0.00 | $0 | | 02/28/2014 |
| 02/28/2014 | LEXICON PHARMACEUTICALS, INC. | LXRX | Payment of Exercise | Common Stock | 29.8k | $1.92 | $57.2k | | 02/28/2014 |
| 02/28/2013 | LEXICON PHARMACEUTICALS, INC. | LXRX | Exercise | Restricted Stock Units (Phantom Stock) | 37k | $0.00 | $0 | | 02/28/2013 |
| 02/28/2013 | LEXICON PHARMACEUTICALS, INC. | LXRX | Exercise | Restricted Stock Units (Phantom Stock) | 36.2k | $0.00 | $0 | | 02/28/2013 |
| 02/28/2013 | LEXICON PHARMACEUTICALS, INC. | LXRX | Payment of Exercise | Common Stock | 20k | $1.98 | $39.7k | | 02/28/2013 |
| 02/08/2013 | LEXICON PHARMACEUTICALS, INC. | LXRX | Grant | Stock Option (Right to Buy) | 560k | $2.09 | $1.2M | | 02/08/2013 |
| 02/08/2013 | LEXICON PHARMACEUTICALS, INC. | LXRX | Grant | Restricted Stock Units (Phantom Stock) | 140k | $0.00 | $0 | | 02/08/2013 |
| 02/15/2012 | LEXICON PHARMACEUTICALS, INC. | LXRX | Grant | Stock Option (Right to Buy) | 592k | $1.80 | $1.1M | | 02/15/2012 |
| 02/15/2012 | LEXICON PHARMACEUTICALS, INC. | LXRX | Grant | Restricted Stock Units (Phantom Stock) | 148k | $0.00 | $0 | | 02/15/2012 |
| 02/23/2011 | LEXICON PHARMACEUTICALS, INC. | LXRX | Grant | Common Stock | 38.7k | $0.00 | $0 | | 02/23/2011 |
| 02/23/2011 | LEXICON PHARMACEUTICALS, INC. | LXRX | Payment of Exercise | Common Stock | 10.5k | $1.81 | $18.9k | | 02/23/2011 |
| 02/23/2011 | LEXICON PHARMACEUTICALS, INC. | LXRX | Grant | Stock Option (Right to Buy) | 580k | $1.81 | $1M | | 02/23/2011 |
| 02/23/2011 | LEXICON PHARMACEUTICALS, INC. | LXRX | Grant | Restricted Stock Units (Phantom Stock) | 145k | $0.00 | $0 | | 02/23/2011 |