| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 05/15/2023 | Amylyx Pharmaceuticals, Inc. | | Sale | Common Stock | 12k | $29.03 | $347.4k | | 05/15/2023 |
| 05/15/2023 | Amylyx Pharmaceuticals, Inc. | | Exercise | Stock Option (right to buy) | 2.2k | $0.37 | $814.4 | | 05/15/2023 |
| 05/15/2023 | Amylyx Pharmaceuticals, Inc. | | Exercise | Stock Option (right to buy) | 9.8k | $6.88 | $67.2k | | 05/15/2023 |
| 03/16/2023 | Amylyx Pharmaceuticals, Inc. | | Sale | Common Stock | 52.2k | $31.85 | $1.7M | | 03/16/2023 |
| 03/16/2023 | Amylyx Pharmaceuticals, Inc. | | Sale | Common Stock | 2.4k | $32.43 | $78.4k | | 03/16/2023 |
| 03/16/2023 | Amylyx Pharmaceuticals, Inc. | | Grant | Common Stock | 9.2k | $0.00 | $0 | | 03/16/2023 |
| 03/16/2023 | Amylyx Pharmaceuticals, Inc. | | Grant | Stock Option (right to buy) | 41.2k | $32.08 | $1.3M | | 03/16/2023 |
| 03/16/2023 | Amylyx Pharmaceuticals, Inc. | | Exercise | Stock Option (right to buy) | 16.7k | $6.88 | $115.2k | | 03/16/2023 |
| 03/16/2023 | Amylyx Pharmaceuticals, Inc. | | Exercise | Stock Option (right to buy) | 30k | $0.37 | $11.1k | | 03/16/2023 |
| 03/16/2023 | Amylyx Pharmaceuticals, Inc. | | Exercise | Stock Option (right to buy) | 2.8k | $0.33 | $920.4 | | 03/16/2023 |
| 03/16/2023 | Amylyx Pharmaceuticals, Inc. | | Grant | Stock Option (right to buy) | 41.2k | $32.08 | $1.3M | | 03/16/2023 |
| 03/16/2023 | Amylyx Pharmaceuticals, Inc. | | Grant | Common Stock | 9.2k | $0.00 | $0 | | 03/16/2023 |
| 03/16/2023 | Amylyx Pharmaceuticals, Inc. | | Sale | Common Stock | 2.4k | $32.43 | $78.4k | | 03/16/2023 |
| 03/16/2023 | Amylyx Pharmaceuticals, Inc. | | Sale | Common Stock | 52.2k | $31.85 | $1.7M | | 03/16/2023 |
| 01/06/2023 | Amylyx Pharmaceuticals, Inc. | | Sale | Common Stock | 1.4k | $36.08 | $50.7k | | 01/06/2023 |
| 01/06/2023 | Amylyx Pharmaceuticals, Inc. | | Sale | Common Stock | 629 | $36.79 | $23.1k | | 01/06/2023 |
| 01/06/2022 | Amylyx Pharmaceuticals, Inc. | | Grant | Stock Option (right to buy) | 127.5k | $19.00 | $2.4M | | 01/06/2022 |
| 01/06/2022 | Amylyx Pharmaceuticals, Inc. | | Grant | Common Stock | 28.3k | $0.00 | $0 | | 01/06/2022 |