| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 02/22/2022 | Xeris Biopharma Holdings, Inc. | | Sale | Common Stock | 11.2k | $2.42 | $27.2k | | 02/22/2022 |
| 02/22/2022 | Xeris Biopharma Holdings, Inc. | | Exercise | Stock Option (Right to Buy) | 11.2k | $0.69 | $7.7k | | 02/22/2022 |
| 01/03/2022 | Xeris Biopharma Holdings, Inc. | | Grant | Common Stock | 75k | $0.00 | $0 | | 01/03/2022 |
| 10/05/2021 | Xeris Biopharma Holdings, Inc. | | Grant | Common Stock | 384.8k | $0.00 | $0 | | 10/05/2021 |
| 10/05/2021 | Xeris Biopharma Holdings, Inc. | | Grant | | 110k | $0.00 | $0 | | 10/05/2021 |
| 10/05/2021 | Xeris Biopharma Holdings, Inc. | | Grant | Stock Option (Right to Buy) | 11.2k | $0.69 | $7.7k | | 10/05/2021 |
| 10/05/2021 | Xeris Biopharma Holdings, Inc. | | Grant | Stock Option (Right to Buy) | 28.1k | $1.55 | $43.5k | | 10/05/2021 |
| 10/05/2021 | Xeris Biopharma Holdings, Inc. | | Grant | Stock Option (Right to Buy) | 11.3k | $1.55 | $17.5k | | 10/05/2021 |
| 10/05/2021 | Xeris Biopharma Holdings, Inc. | | Grant | Stock Option (Right to Buy) | 14k | $5.93 | $83.2k | | 10/05/2021 |
| 10/05/2021 | Xeris Biopharma Holdings, Inc. | | Grant | Stock Option (Right to Buy) | 25k | $13.88 | $347k | | 10/05/2021 |
| 10/05/2021 | Xeris Biopharma Holdings, Inc. | | Grant | Stock Option (Right to Buy) | 25k | $3.94 | $98.5k | | 10/05/2021 |
| 10/05/2021 | XERIS PHARMACEUTICALS INC | XERS | Disposition | Common Stock | 384.8k | $0.00 | $0 | | 10/05/2021 |
| 10/05/2021 | XERIS PHARMACEUTICALS INC | XERS | Disposition | | 110k | $0.00 | $0 | | 10/05/2021 |
| 10/05/2021 | XERIS PHARMACEUTICALS INC | XERS | Disposition | Stock Option (Right to Buy) | 11.2k | $0.69 | $7.7k | | 10/05/2021 |
| 10/05/2021 | XERIS PHARMACEUTICALS INC | XERS | Disposition | Stock Option (Right to Buy) | 28.1k | $1.55 | $43.5k | | 10/05/2021 |
| 10/05/2021 | XERIS PHARMACEUTICALS INC | XERS | Disposition | Stock Option (Right to Buy) | 11.3k | $1.55 | $17.5k | | 10/05/2021 |
| 10/05/2021 | XERIS PHARMACEUTICALS INC | XERS | Disposition | Stock Option (Right to Buy) | 14k | $5.93 | $83.2k | | 10/05/2021 |
| 10/05/2021 | XERIS PHARMACEUTICALS INC | XERS | Disposition | Stock Option (Right to Buy) | 25k | $13.88 | $347k | | 10/05/2021 |
| 10/05/2021 | XERIS PHARMACEUTICALS INC | XERS | Disposition | Stock Option (Right to Buy) | 25k | $3.94 | $98.5k | | 10/05/2021 |
| 04/12/2021 | XERIS PHARMACEUTICALS INC | XERS | Sale | Common Stock | 10k | $4.07 | $40.7k | | 04/12/2021 |
| 01/29/2021 | XERIS PHARMACEUTICALS INC | XERS | Grant | Common Stock | 100k | $0.00 | $0 | | 01/29/2021 |
| 01/13/2021 | XERIS PHARMACEUTICALS INC | XERS | Sale | Common Stock | 10k | $6.01 | $60.1k | | 01/13/2021 |
| 01/11/2021 | XERIS PHARMACEUTICALS INC | XERS | Sale | Common Stock | 10k | $5.72 | $57.2k | | 01/11/2021 |
| 12/16/2020 | XERIS PHARMACEUTICALS INC | XERS | Gift | Common Stock | 10k | $0.00 | $0 | | 12/16/2020 |
| 08/14/2020 | XERIS PHARMACEUTICALS INC | XERS | Grant | Stock Option (Right to Buy) | 25k | $4.19 | $104.8k | | 08/14/2020 |
| 01/31/2020 | XERIS PHARMACEUTICALS INC | XERS | Grant | Common Stock | 15k | $0.00 | $0 | | 01/31/2020 |
| 01/13/2020 | XERIS PHARMACEUTICALS INC | XERS | Sale | Common Stock | 10k | $5.50 | $55k | | 01/13/2020 |
| 11/19/2019 | XERIS PHARMACEUTICALS INC | XERS | Gift | Common Stock | 17.5k | $0.00 | $0 | | 11/19/2019 |
| 10/11/2019 | XERIS PHARMACEUTICALS INC | XERS | Sale | Common Stock | 10k | $7.97 | $79.7k | | 01/14/2019 |
| 07/11/2019 | XERIS PHARMACEUTICALS INC | XERS | Sale | Common Stock | 38 | $12.70 | $482.6 | | 01/14/2019 |
| 07/11/2019 | XERIS PHARMACEUTICALS INC | XERS | Sale | Common Stock | 10k | $12.04 | $119.9k | | 01/14/2019 |
| 04/11/2019 | XERIS PHARMACEUTICALS INC | XERS | Sale | Common Stock | 10k | $9.56 | $95.6k | | 04/11/2019 |
| 01/31/2019 | XERIS PHARMACEUTICALS INC | XERS | Grant | Stock Option (right to buy) | 25k | $13.88 | $347k | | 01/31/2019 |
| 01/14/2019 | XERIS PHARMACEUTICALS INC | XERS | Sale | Common Stock | 7.7k | $17.20 | $132.5k | | 01/14/2019 |
| 01/11/2019 | XERIS PHARMACEUTICALS INC | XERS | Sale | Common Stock | 2.3k | $0.00 | $0 | | 01/11/2019 |
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