| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 07/03/2023 | Apellis Pharmaceuticals, Inc. | APLS | Sale | Common Stock | 8.5k | $89.98 | $765.7k | | 07/03/2023 |
| 06/28/2023 | Apellis Pharmaceuticals, Inc. | APLS | Gift | Common Stock | 12.8k | $0.00 | $0 | | 06/28/2023 |
| 06/28/2023 | Apellis Pharmaceuticals, Inc. | APLS | Gift | Common Stock | 12.8k | $0.00 | $0 | Indirect Owner (The David O. Watson Irrevocable Trust of 2023) | 06/28/2023 |
| 02/21/2023 | Apellis Pharmaceuticals, Inc. | APLS | Grant | Stock Option (Right to Buy) | 14k | $35.46 | $497.3k | | 02/21/2023 |
| 02/21/2023 | Apellis Pharmaceuticals, Inc. | APLS | Payment of Exercise | Common Stock | 825 | $58.50 | $48.3k | | 02/21/2023 |
| 02/21/2023 | Apellis Pharmaceuticals, Inc. | APLS | Grant | Common Stock | 9.9k | $0.00 | $0 | | 02/21/2023 |
| 02/10/2023 | Apellis Pharmaceuticals, Inc. | APLS | Payment of Exercise | Common Stock | 532 | $51.21 | $27.2k | | 02/10/2023 |
| 01/27/2023 | Apellis Pharmaceuticals, Inc. | APLS | Payment of Exercise | Common Stock | 551 | $52.77 | $29.1k | | 01/27/2023 |
| 01/20/2023 | Apellis Pharmaceuticals, Inc. | APLS | Payment of Exercise | Common Stock | 2k | $52.05 | $105.9k | | 01/20/2023 |
| 06/22/2022 | Apellis Pharmaceuticals, Inc. | APLS | Sale | Common Stock | 10k | $44.51 | $445.1k | | 06/22/2022 |
| 04/25/2022 | Apellis Pharmaceuticals, Inc. | APLS | Sale | Common Stock | 5k | $50.00 | $250k | | 04/21/2022 |
| 04/21/2022 | Apellis Pharmaceuticals, Inc. | APLS | Other (disposition) | Stock Option (Right to Buy) | 11.2k | $44.90 | $505.1k | | 04/21/2022 |
| 04/21/2022 | Apellis Pharmaceuticals, Inc. | APLS | Other (disposition) | Common Stock | 1.9k | $0.00 | $0 | | 04/21/2022 |
| 02/10/2022 | Apellis Pharmaceuticals, Inc. | APLS | Payment of Exercise | Common Stock | 491 | $47.12 | $23.1k | | 02/10/2022 |
| 01/28/2022 | Apellis Pharmaceuticals, Inc. | APLS | Payment of Exercise | Common Stock | 650 | $38.59 | $25.1k | | 01/28/2022 |
| 01/21/2022 | Apellis Pharmaceuticals, Inc. | APLS | Grant | Common Stock | 26.1k | $0.00 | $0 | | 01/21/2022 |
| 01/21/2022 | Apellis Pharmaceuticals, Inc. | APLS | Grant | Stock Option (Right to Buy) | 37k | $35.46 | $1.3M | | 01/21/2022 |
| 12/27/2021 | Apellis Pharmaceuticals, Inc. | APLS | Sale | Common Stock | 1.2k | $48.50 | $58.2k | | 12/27/2021 |
| 12/22/2021 | Apellis Pharmaceuticals, Inc. | APLS | Sale | Common Stock | 5.2k | $47.72 | $246.9k | | 12/22/2021 |
| 12/22/2021 | Apellis Pharmaceuticals, Inc. | APLS | Sale | Common Stock | 5.1k | $47.86 | $243.9k | | 12/22/2021 |
| 12/22/2021 | Apellis Pharmaceuticals, Inc. | APLS | Sale | Common Stock | 300 | $48.58 | $14.6k | | 12/22/2021 |
| 12/22/2021 | Apellis Pharmaceuticals, Inc. | APLS | Exercise | Stock Option (Right to Buy) | 5.2k | $13.85 | $71.7k | | 12/22/2021 |
| 12/22/2021 | Apellis Pharmaceuticals, Inc. | APLS | Exercise | Stock Option (Right to Buy) | 4.8k | $13.85 | $66.8k | | 12/22/2021 |
| 12/22/2021 | Apellis Pharmaceuticals, Inc. | APLS | Exercise | Stock Option (Right to Buy) | 4.7k | $14.95 | $70.5k | | 12/22/2021 |
| 12/22/2021 | Apellis Pharmaceuticals, Inc. | APLS | Exercise | Stock Option (Right to Buy) | 5.4k | $14.95 | $80.7k | | 12/22/2021 |
| 09/10/2021 | Apellis Pharmaceuticals, Inc. | APLS | Exercise | Stock Option (Right to Buy) | 954 | $4.31 | $4.1k | | 09/10/2021 |
| 06/21/2021 | Apellis Pharmaceuticals, Inc. | APLS | Exercise | Stock Option (Right to Buy) | 489 | $4.31 | $2.1k | | 06/21/2021 |
| 05/28/2021 | Apellis Pharmaceuticals, Inc. | APLS | Exercise | Stock Option (Right to Buy) | 489 | $4.31 | $2.1k | | 05/28/2021 |
| 04/22/2021 | Apellis Pharmaceuticals, Inc. | APLS | Exercise | Stock Option (Right to Buy) | 489 | $4.31 | $2.1k | | 04/22/2021 |
| 03/22/2021 | Apellis Pharmaceuticals, Inc. | APLS | Exercise | Stock Option (Right to Buy) | 978 | $4.31 | $4.2k | | 03/22/2021 |
| 02/10/2021 | Apellis Pharmaceuticals, Inc. | APLS | Payment of Exercise | Common Stock | 468 | $47.72 | $22.3k | | 02/10/2021 |
| 01/28/2021 | Apellis Pharmaceuticals, Inc. | APLS | Grant | Common Stock | 7.5k | $0.00 | $0 | | 01/28/2021 |
| 01/28/2021 | Apellis Pharmaceuticals, Inc. | APLS | Grant | Common Stock | 1.9k | $0.00 | $0 | | 01/28/2021 |
| 01/28/2021 | Apellis Pharmaceuticals, Inc. | APLS | Grant | Stock Option (Right to Buy) | 45k | $44.90 | $2M | | 01/28/2021 |
| 01/28/2021 | Apellis Pharmaceuticals, Inc. | APLS | Grant | Stock Option (Right to Buy) | 11.2k | $44.90 | $505.1k | | 01/28/2021 |
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