| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 05/24/2023 | Apellis Pharmaceuticals, Inc. | APLS | Gift | Common Stock | 20k | $0.00 | $0 | Indirect Owner (The Cedric Francois Irrevocable Trust of 2023) | 05/24/2023 |
| 05/24/2023 | Apellis Pharmaceuticals, Inc. | APLS | Gift | Common Stock | 20k | $0.00 | $0 | | 05/24/2023 |
| 05/17/2023 | Apellis Pharmaceuticals, Inc. | APLS | Exercise | Stock Option (Right to Buy) | 20k | $2.67 | $53.4k | | 05/16/2023 |
| 05/16/2023 | Apellis Pharmaceuticals, Inc. | APLS | Sale | Common Stock | 934 | $83.17 | $77.7k | | 05/16/2023 |
| 05/16/2023 | Apellis Pharmaceuticals, Inc. | APLS | Sale | Common Stock | 1.8k | $83.85 | $150.9k | | 05/16/2023 |
| 05/16/2023 | Apellis Pharmaceuticals, Inc. | APLS | Sale | Common Stock | 14.6k | $85.01 | $1.2M | | 05/16/2023 |
| 05/16/2023 | Apellis Pharmaceuticals, Inc. | APLS | Sale | Common Stock | 3k | $85.90 | $258.3k | | 05/16/2023 |
| 05/16/2023 | Apellis Pharmaceuticals, Inc. | APLS | Sale | Common Stock | 7.5k | $87.02 | $655.1k | | 05/16/2023 |
| 05/16/2023 | Apellis Pharmaceuticals, Inc. | APLS | Sale | Common Stock | 2.1k | $87.67 | $185.9k | | 05/16/2023 |
| 05/16/2023 | Apellis Pharmaceuticals, Inc. | APLS | Exercise | Stock Option (Right to Buy) | 30k | $2.67 | $80.1k | | 05/16/2023 |
| 04/05/2023 | Apellis Pharmaceuticals, Inc. | APLS | Gift | Common Stock | 27k | $0.00 | $0 | Indirect Owner (The Cedric Francois Irrevocable Trust of 2023) | 04/03/2023 |
| 04/05/2023 | Apellis Pharmaceuticals, Inc. | APLS | Gift | Common Stock | 27k | $0.00 | $0 | | 04/03/2023 |
| 04/04/2023 | Apellis Pharmaceuticals, Inc. | APLS | Gift | Common Stock | 380k | $0.00 | $0 | | 04/03/2023 |
| 04/04/2023 | Apellis Pharmaceuticals, Inc. | APLS | Gift | Common Stock | 380k | $0.00 | $0 | Indirect Owner (The Cedric Francois Irrevocable Trust of 2023) | 04/03/2023 |
| 04/03/2023 | Apellis Pharmaceuticals, Inc. | APLS | Gift | Common Stock | 227.2k | $0.00 | $0 | | 04/03/2023 |
| 04/03/2023 | Apellis Pharmaceuticals, Inc. | APLS | Gift | Common Stock | 227.2k | $0.00 | $0 | Indirect Owner (The Cedric Francois Irrevocable Trust of 2023) | 04/03/2023 |
| 03/22/2023 | Apellis Pharmaceuticals, Inc. | APLS | Exercise | Stock Option (Right to Buy) | 20k | $2.67 | $53.4k | | 03/21/2023 |
| 03/22/2023 | Apellis Pharmaceuticals, Inc. | APLS | Exercise | Stock Option (Right to Buy) | 100k | $3.76 | $376k | | 03/21/2023 |
| 03/22/2023 | Apellis Pharmaceuticals, Inc. | APLS | Exercise | Stock Option (Right to Buy) | 7.2k | $13.85 | $100k | | 03/21/2023 |
| 03/21/2023 | Apellis Pharmaceuticals, Inc. | APLS | Sale | Common Stock | 30k | $62.74 | $1.9M | | 03/21/2023 |
| 03/21/2023 | Apellis Pharmaceuticals, Inc. | APLS | Exercise | Stock Option (Right to Buy) | 30k | $2.67 | $80.1k | | 03/21/2023 |
| 02/27/2023 | Apellis Pharmaceuticals, Inc. | APLS | Exercise | Stock Option (Right to Buy) | 100k | $3.76 | $376k | | 02/27/2023 |
| 02/21/2023 | Apellis Pharmaceuticals, Inc. | APLS | Grant | Common Stock | 13.9k | $0.00 | $0 | | 02/21/2023 |
| 02/21/2023 | Apellis Pharmaceuticals, Inc. | APLS | Payment of Exercise | Common Stock | 1.6k | $58.50 | $93.7k | | 02/21/2023 |
| 02/21/2023 | Apellis Pharmaceuticals, Inc. | APLS | Grant | Stock Option (Right to Buy) | 19.7k | $35.46 | $699.6k | | 02/21/2023 |
| 01/27/2023 | Apellis Pharmaceuticals, Inc. | APLS | Payment of Exercise | Common Stock | 2.9k | $52.77 | $151.9k | | 01/27/2023 |
| 01/20/2023 | Apellis Pharmaceuticals, Inc. | APLS | Payment of Exercise | Common Stock | 9.5k | $52.05 | $492k | | 01/20/2023 |
| 12/19/2022 | Apellis Pharmaceuticals, Inc. | APLS | Sale | Common Stock | 3.8k | $51.97 | $194.9k | | 04/25/2022 |
| 12/19/2022 | Apellis Pharmaceuticals, Inc. | APLS | Sale | Common Stock | 24.4k | $52.07 | $1.3M | | 04/25/2022 |
| 12/19/2022 | Apellis Pharmaceuticals, Inc. | APLS | Exercise | Stock Option (Right to Buy) | 28.2k | $2.67 | $75.3k | | 04/25/2022 |
| 12/19/2022 | Apellis Pharmaceuticals, Inc. | APLS | Exercise | Stock Option (Right to Buy) | 15k | $3.76 | $56.4k | | 04/25/2022 |
| 12/19/2022 | Apellis Pharmaceuticals, Inc. | APLS | Exercise | Stock Option (Right to Buy) | 6.7k | $14.95 | $100k | | 04/25/2022 |
| 04/25/2022 | Apellis Pharmaceuticals, Inc. | APLS | Other (disposition) | Common Stock | 12.5k | $0.00 | $0 | | 04/25/2022 |
| 02/10/2022 | Apellis Pharmaceuticals, Inc. | APLS | Payment of Exercise | Common Stock | 2.5k | $47.12 | $118.9k | | 02/10/2022 |
| 01/28/2022 | Apellis Pharmaceuticals, Inc. | APLS | Payment of Exercise | Common Stock | 2k | $38.59 | $78.1k | | 01/28/2022 |
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