| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 11/14/2021 | Prometheus Biosciences, Inc. | RXDX | Grant | Stock Option (Right to Buy) | 54.1k | $36.32 | $2M | | 11/14/2021 |
| 08/06/2019 | Sienna Biopharmaceuticals, Inc. | SNNA | Grant | Stock Options (Right to buy) | 22.5k | $0.71 | $16k | | 08/06/2019 |
| 08/06/2019 | Sienna Biopharmaceuticals, Inc. | SNNA | Grant | Stock Options (Right to buy) | 18.3k | $0.71 | $13k | | 08/06/2019 |
| 08/06/2019 | Sienna Biopharmaceuticals, Inc. | SNNA | Grant | Stock Options (Right to buy) | 60k | $0.71 | $42.6k | | 08/06/2019 |
| 08/06/2019 | Sienna Biopharmaceuticals, Inc. | SNNA | Grant | Stock Options (Right to buy) | 8.5k | $0.71 | $6k | | 08/06/2019 |
| 08/06/2019 | Sienna Biopharmaceuticals, Inc. | SNNA | Disposition | Stock Options (Right to buy) | 22.5k | $2.32 | $52.2k | | 08/06/2019 |
| 08/06/2019 | Sienna Biopharmaceuticals, Inc. | SNNA | Disposition | Stock Options (Right to buy) | 18.3k | $2.32 | $42.4k | | 08/06/2019 |
| 08/06/2019 | Sienna Biopharmaceuticals, Inc. | SNNA | Disposition | Stock Options (Right to buy) | 8.5k | $15.00 | $127.8k | | 08/06/2019 |
| 08/06/2019 | Sienna Biopharmaceuticals, Inc. | SNNA | Disposition | Stock Options (Right to buy) | 60k | $15.08 | $904.8k | | 08/06/2019 |
| 08/06/2019 | Sienna Biopharmaceuticals, Inc. | SNNA | Grant | Common Stock | 50k | $0.00 | $0 | | 08/06/2019 |
| 07/02/2019 | Sienna Biopharmaceuticals, Inc. | SNNA | Payment of Exercise | Common Stock | 4.1k | $0.76 | $3.1k | | 07/02/2019 |
| 01/01/2019 | Sienna Biopharmaceuticals, Inc. | SNNA | Grant | Common Stock | 45k | $0.00 | $0 | | 01/01/2019 |
| 01/01/2019 | Sienna Biopharmaceuticals, Inc. | SNNA | Grant | Stock Options (Right to buy) | 18.3k | $2.32 | $42.4k | | 01/01/2019 |
| 01/01/2019 | Sienna Biopharmaceuticals, Inc. | SNNA | Grant | Stock Options (Right to buy) | 22.5k | $2.32 | $52.2k | | 01/01/2019 |
| 06/01/2018 | Sienna Biopharmaceuticals, Inc. | SNNA | Grant | Stock Options (Right to buy) | 60k | $15.08 | $904.8k | | 06/01/2018 |