| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 03/28/2022 | Edesa Biotech, Inc. | SBOT | Grant | Stock Option (right to buy) | 30k | $2.94 | $88.2k | | 03/28/2022 |
| 06/11/2021 | Endo International plc | ENDP | Payment of Exercise | Ordinary Shares | 23k | $6.26 | $144k | | 06/11/2021 |
| 06/11/2021 | Endo International plc | ENDP | Grant | Ordinary Shares | 47.9k | $0.00 | $0 | | 06/11/2021 |
| 12/02/2020 | BIOSPECIFICS TECHNOLOGIES CORP | BSTC | Disposition | Stock Option (Right to Buy) | 5k | $55.62 | $278.1k | | 12/02/2020 |
| 12/02/2020 | BIOSPECIFICS TECHNOLOGIES CORP | BSTC | Disposition | Stock Option (Right to Buy) | 15k | $41.82 | $627.3k | | 12/02/2020 |
| 12/02/2020 | BIOSPECIFICS TECHNOLOGIES CORP | BSTC | Disposition | Stock Option (Right to Buy) | 1.7k | $37.64 | $63.5k | | 12/02/2020 |
| 12/02/2020 | BIOSPECIFICS TECHNOLOGIES CORP | BSTC | Disposition | Common Stock, $0.001 par value | 1.7k | $0.00 | $0 | | 12/02/2020 |
| 12/02/2020 | BIOSPECIFICS TECHNOLOGIES CORP | BSTC | Disposition | Common Stock, $0.001 par value | 1.9k | $0.00 | $0 | | 12/02/2020 |
| 07/15/2020 | BIOSPECIFICS TECHNOLOGIES CORP | BSTC | Grant | Common Stock, $0.001 par value | 1.7k | $0.00 | $0 | | 07/15/2020 |
| 03/13/2020 | BIOSPECIFICS TECHNOLOGIES CORP | BSTC | Grant | Stock Option (Right to Buy) | 5k | $55.62 | $278.1k | | 03/13/2020 |
| 07/01/2019 | BIOSPECIFICS TECHNOLOGIES CORP | BSTC | Grant | Common Stock, $0.001 par value | 1.9k | $0.00 | $0 | | 07/01/2019 |
| 06/07/2019 | BIOSPECIFICS TECHNOLOGIES CORP | BSTC | Sale | Common Stock, $0.001 par value | 459 | $58.55 | $26.9k | | 06/07/2019 |
| 06/05/2019 | BIOSPECIFICS TECHNOLOGIES CORP | BSTC | Sale | Common Stock, $0.001 par value | 2.4k | $58.01 | $139.9k | | 06/04/2019 |
| 06/05/2019 | BIOSPECIFICS TECHNOLOGIES CORP | BSTC | Sale | Common Stock, $0.001 par value | 500 | $57.25 | $28.6k | | 06/04/2019 |
| 06/04/2019 | BIOSPECIFICS TECHNOLOGIES CORP | BSTC | Sale | Common Stock, $0.001 par value | 2.6k | $56.56 | $147.1k | | 06/04/2019 |
| 05/29/2019 | BIOSPECIFICS TECHNOLOGIES CORP | BSTC | Sale | Common Stock, $0.001 par value | 3.3k | $60.74 | $201.2k | | 05/29/2019 |
| 05/22/2019 | BIOSPECIFICS TECHNOLOGIES CORP | BSTC | Exercise | Stock Option (right to buy) | 8k | $37.64 | $301.1k | | 05/22/2019 |
| 05/17/2019 | BIOSPECIFICS TECHNOLOGIES CORP | BSTC | Sale | Common Stock, $0.001 par value | 2k | $63.43 | $126.9k | | 05/17/2019 |
| 05/17/2019 | BIOSPECIFICS TECHNOLOGIES CORP | BSTC | Sale | Common Stock, $0.001 par value | 2k | $64.00 | $128k | | 05/17/2019 |
| 05/16/2019 | BIOSPECIFICS TECHNOLOGIES CORP | BSTC | Exercise | Stock Option (right to buy) | 5.3k | $37.64 | $200k | | 05/16/2019 |
| 03/15/2018 | BIOSPECIFICS TECHNOLOGIES CORP | BSTC | Grant | Stock Option (Right to Buy) | 15k | $41.82 | $627.3k | | 03/15/2018 |