| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 04/17/2019 | OSIRIS THERAPEUTICS, INC. | OSIR | Disposition | Non-Qualified Stock Option (right to buy) | 17.4k | $18.40 | $319.4k | | 04/17/2019 |
| 04/17/2019 | OSIRIS THERAPEUTICS, INC. | OSIR | Disposition | Incentive Stock Option (right to buy) | 7.6k | $18.40 | $140.6k | | 04/17/2019 |
| 04/17/2019 | OSIRIS THERAPEUTICS, INC. | OSIR | Disposition | Incentive Stock Option (right to buy) | 18.6k | $14.00 | $259.9k | | 04/17/2019 |
| 04/17/2019 | OSIRIS THERAPEUTICS, INC. | OSIR | Disposition | Non-Qualified Stock Option (right to buy) | 1.4k | $14.00 | $20.1k | | 04/17/2019 |
| 04/17/2019 | OSIRIS THERAPEUTICS, INC. | OSIR | Disposition | Incentive Stock Option (right to buy) | 10k | $7.73 | $77.3k | | 04/17/2019 |
| 04/17/2019 | OSIRIS THERAPEUTICS, INC. | OSIR | Disposition | Incentive Stock Option (right to buy) | 6k | $5.08 | $30.5k | | 04/17/2019 |
| 04/17/2019 | OSIRIS THERAPEUTICS, INC. | OSIR | Disposition | Incentive Stock Option (right to buy) | 9k | $7.13 | $64.2k | | 04/17/2019 |
| 04/17/2019 | OSIRIS THERAPEUTICS, INC. | OSIR | Disposition | Incentive Stock Option (right to buy) | 5k | $6.46 | $32.3k | | 04/17/2019 |
| 04/17/2019 | OSIRIS THERAPEUTICS, INC. | OSIR | Disposition | Incentive Stock Option (right to buy) | 8k | $7.74 | $61.9k | | 04/17/2019 |
| 04/17/2019 | OSIRIS THERAPEUTICS, INC. | OSIR | Disposition | Common Stock | 9.4k | $19.00 | $178.1k | | 04/17/2019 |
| 04/17/2019 | OSIRIS THERAPEUTICS, INC. | OSIR | Disposition | Incentive Stock Option (right to buy) | 25k | $6.80 | $170k | | 04/17/2019 |
| 04/17/2019 | OSIRIS THERAPEUTICS, INC. | OSIR | Disposition | Non-Qualified Stock Option (right to buy) | 25k | $6.80 | $170k | | 04/17/2019 |
| 07/19/2017 | OSIRIS THERAPEUTICS, INC. | OSIR | Grant | Non-qualified Stock Option (right to buy) | 15.5k | $6.80 | $105.2k | | 07/19/2017 |
| 07/19/2017 | OSIRIS THERAPEUTICS, INC. | OSIR | Grant | Incentive Stock Option (right to buy) | 34.5k | $6.80 | $234.8k | | 07/19/2017 |