EMPFIELD JAMES R. [Rocket]

Date	Name	Symbol	Type	Security	Shares	Price	Value	Reported
03/10/2023	Xenon Pharmaceuticals Inc.	XENE	Grant	Stock Option (Right to Buy)	75k	$34.18	$2.6M	03/10/2023
08/12/2022	Xenon Pharmaceuticals Inc.	XENE	Exercise	Stock Option (Right to Buy)	45k	$4.75	$213.8k	08/12/2022
08/12/2022	Xenon Pharmaceuticals Inc.	XENE	Exercise	Stock Option (Right to Buy)	20k	$3.10	$62k	08/12/2022
08/12/2022	Xenon Pharmaceuticals Inc.	XENE	Sale	Common Shares	21.9k	$38.68	$846.1k	08/12/2022
08/12/2022	Xenon Pharmaceuticals Inc.	XENE	Sale	Common Shares	35.9k	$38.08	$1.4M	08/12/2022
08/12/2022	Xenon Pharmaceuticals Inc.	XENE	Payment of Exercise	Common Shares	7.3k	$38.02	$275.9k	08/12/2022
03/10/2022	Xenon Pharmaceuticals Inc.	XENE	Grant	Stock Option (Right to Buy)	65k	$30.01	$2M	03/10/2022
03/07/2022	Xenon Pharmaceuticals Inc.	XENE	Payment of Exercise	Common Shares	695	$30.23	$21k	03/04/2022
03/07/2022	Xenon Pharmaceuticals Inc.	XENE	Payment of Exercise	Common Shares	9k	$30.23	$270.6k	03/04/2022
03/07/2022	Xenon Pharmaceuticals Inc.	XENE	Sale	Common Shares	1.8k	$30.62	$55.3k	03/04/2022
03/07/2022	Xenon Pharmaceuticals Inc.	XENE	Sale	Common Shares	31k	$30.54	$948.2k	03/04/2022
03/07/2022	Xenon Pharmaceuticals Inc.	XENE	Exercise	Stock Option (Right to Buy)	2.5k	$8.40	$21k	03/04/2022
03/07/2022	Xenon Pharmaceuticals Inc.	XENE	Exercise	Stock Option (Right to Buy)	40k	$6.76	$270.4k	03/04/2022
03/04/2022	Xenon Pharmaceuticals Inc.	XENE	Payment of Exercise	Common Shares	6.7k	$31.42	$210k	03/04/2022
03/04/2022	Xenon Pharmaceuticals Inc.	XENE	Sale	Common Shares	18.3k	$30.79	$563.9k	03/04/2022
03/04/2022	Xenon Pharmaceuticals Inc.	XENE	Exercise	Stock Option (Right to Buy)	25k	$8.40	$210k	03/04/2022
03/12/2021	Xenon Pharmaceuticals Inc.	XENE	Grant	Stock Option (Right to Buy)	65k	$20.55	$1.3M	03/12/2021
03/12/2020	Xenon Pharmaceuticals Inc.	XENE	Grant	Stock Option (Right to Buy)	65k	$11.58	$752.7k	03/12/2020
09/16/2019	Xenon Pharmaceuticals Inc.	XENE	Grant	Stock Option (Right to Buy)	40k	$9.44	$377.6k	09/16/2019
03/12/2018	Xenon Pharmaceuticals Inc.	XENE	Grant	Stock Option (Right to Buy)	45k	$4.75	$213.8k	03/12/2018
10/23/2017	Xenon Pharmaceuticals Inc.	XENE	Grant	Stock Option (Right to Buy)	20k	$3.10	$62k	10/23/2017
08/15/2017	Xenon Pharmaceuticals Inc.	XENE	Purchase	Common Shares	10k	$2.48	$24.8k	08/15/2017
03/13/2017	Xenon Pharmaceuticals Inc.	XENE	Grant	Stock Option (Right to Buy)	27.5k	$8.40	$231k	03/13/2017
02/08/2016	Xenon Pharmaceuticals Inc.	XENE	Grant	Stock Option (Right to Buy)	40k	$6.76	$270.4k	02/08/2016