| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 06/28/2023 | Morphic Holding, Inc. | MORF | Other (disposition) | Common Stock | 93.5k | $0.00 | $0 | By Polaris Partners VII, L.P. | 06/28/2023 |
| 06/28/2023 | Morphic Holding, Inc. | MORF | Other (acquisition) | Common Stock | 935 | $0.00 | $0 | By Polaris Management Co. VII L.L.C. | 06/28/2023 |
| 06/28/2023 | Morphic Holding, Inc. | MORF | Other (disposition) | Common Stock | 935 | $0.00 | $0 | By Polaris Management Co. VII L.L.C. | 06/28/2023 |
| 06/28/2023 | Morphic Holding, Inc. | MORF | Other (acquisition) | Common Stock | 145 | $0.00 | $0 | | 06/28/2023 |
| 06/28/2023 | Morphic Holding, Inc. | MORF | Other (disposition) | Common Stock | 6.5k | $0.00 | $0 | By Polaris Entrepreneurs' Fund VII, L.P. | 06/28/2023 |
| 06/01/2023 | Morphic Holding, Inc. | MORF | Grant | Director Stock Option (Right to Buy) | 12.5k | $56.47 | $707.9k | | 06/01/2023 |
| 06/22/2022 | Scholar Rock Holding Corp | SRRK | Purchase | Common Stock | 1.1M | $4.90 | $5.5M | See Footnote | 06/22/2022 |
| 06/22/2022 | Scholar Rock Holding Corp | SRRK | Purchase | Common Stock | 66.1k | $4.90 | $324.1k | See Footnote | 06/22/2022 |
| 06/22/2022 | Scholar Rock Holding Corp | SRRK | Purchase | Common Warrant (right to buy) | 283k | $7.35 | $2.1M | See Footnote | 06/22/2022 |
| 06/22/2022 | Scholar Rock Holding Corp | SRRK | Purchase | Common Warrant (right to buy) | 16.5k | $7.35 | $121.5k | See Footnote | 06/22/2022 |
| 06/08/2022 | Morphic Holding, Inc. | MORF | Grant | Director Stock Option (Right to Buy) | 17.6k | $24.49 | $429.8k | | 06/08/2022 |
| 06/01/2022 | Syros Pharmaceuticals, Inc. | SYRS | Grant | Stock Option (right to buy) | 17.5k | $0.78 | $13.6k | | 06/01/2022 |
| 05/26/2022 | Scholar Rock Holding Corp | SRRK | Grant | Stock Option (Right to Buy) | 28k | $4.75 | $133k | | 05/26/2022 |
| 05/18/2022 | Metacrine, Inc. | MTCR | Grant | Stock Option (right to buy) | 16.5k | $0.42 | $6.9k | | 05/18/2022 |
| 11/17/2021 | Scholar Rock Holding Corp | SRRK | Other (disposition) | Common Stock | 267.6k | $0.00 | $0 | See Footnote | 11/17/2021 |
| 11/17/2021 | Scholar Rock Holding Corp | SRRK | Other (acquisition) | Common Stock | 55.7k | $0.00 | $0 | See Footnote | 11/17/2021 |
| 11/17/2021 | Scholar Rock Holding Corp | SRRK | Other (disposition) | Common Stock | 55.7k | $0.00 | $0 | See Footnote | 11/17/2021 |
| 11/17/2021 | Scholar Rock Holding Corp | SRRK | Other (acquisition) | Common Stock | 7.4k | $0.00 | $0 | | 11/17/2021 |
| 11/17/2021 | Scholar Rock Holding Corp | SRRK | Other (disposition) | Common Stock | 15.6k | $0.00 | $0 | See Footnote | 11/17/2021 |
| 11/17/2021 | Scholar Rock Holding Corp | SRRK | Other (acquisition) | Common Stock | 182 | $0.00 | $0 | See Footnote | 11/17/2021 |
| 11/17/2021 | Scholar Rock Holding Corp | SRRK | Other (acquisition) | Common Stock | 160 | $0.00 | $0 | See Footnote | 11/17/2021 |
| 11/17/2021 | Scholar Rock Holding Corp | SRRK | Other (disposition) | Common Stock | 160 | $0.00 | $0 | See Footnote | 11/17/2021 |
| 11/17/2021 | Scholar Rock Holding Corp | SRRK | Other (acquisition) | Common Stock | 21 | $0.00 | $0 | | 11/17/2021 |
| 06/16/2021 | Morphic Holding, Inc. | MORF | Grant | Director Stock Option (right to buy) | 9.9k | $64.79 | $642.1k | | 06/16/2021 |
| 06/16/2021 | Morphic Holding, Inc. | MORF | Grant | Director Stock Option (right to buy) | 12k | $64.79 | $777.5k | | 06/16/2021 |
| 06/08/2021 | Syros Pharmaceuticals, Inc. | SYRS | Grant | Stock Option (right to buy) | 17.5k | $6.30 | $110.2k | | 06/08/2021 |
| 05/27/2021 | Scholar Rock Holding Corp | SRRK | Grant | Stock Option (Right to Buy) | 7.8k | $26.78 | $208.9k | | 05/27/2021 |
| 05/24/2021 | Metacrine, Inc. | MTCR | Grant | Stock Option (right to buy) | 16.5k | $4.07 | $67.2k | | 05/24/2021 |
| 05/21/2021 | Morphic Holding, Inc. | MORF | Sale | Common Stock | 217.1k | $45.50 | $9.9M | By Polaris Partners VII, L.P. | 05/21/2021 |
| 05/21/2021 | Morphic Holding, Inc. | MORF | Sale | Common Stock | 15.2k | $45.50 | $691.1k | By Polaris Entrepreneurs' Fund VII, L.P. | 05/21/2021 |
| 09/18/2020 | Metacrine, Inc. | MTCR | Conversion | Series A Convertible Preferred Stock | 128.2k | $0.00 | $0 | See footnote | 09/18/2020 |
| 09/18/2020 | Metacrine, Inc. | MTCR | Conversion | Series B Convertible Preferred Stock | 451.7k | $0.00 | $0 | See footnote | 09/18/2020 |
| 09/18/2020 | Metacrine, Inc. | MTCR | Conversion | Series B Convertible Preferred Stock | 20.6k | $0.00 | $0 | See footnote | 09/18/2020 |
| 09/18/2020 | Metacrine, Inc. | MTCR | Conversion | Series C Convertible Preferred Stock | 216.1k | $0.00 | $0 | See footnote | 09/18/2020 |
| 09/18/2020 | Metacrine, Inc. | MTCR | Conversion | Series C Convertible Preferred Stock | 15.1k | $0.00 | $0 | See footnote | 09/18/2020 |
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