| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 03/09/2018 | Cascadian Therapeutics, Inc. | CASC | Disposition | Stock Option (Right to buy) | 8.3k | $28.44 | $237k | | 03/09/2018 |
| 03/09/2018 | Cascadian Therapeutics, Inc. | CASC | Disposition | Stock Option (Right to buy) | 25k | $10.44 | $261k | | 03/09/2018 |
| 03/09/2018 | Cascadian Therapeutics, Inc. | CASC | Disposition | Stock Option (Right to buy) | 25k | $10.56 | $264k | | 03/09/2018 |
| 03/09/2018 | Cascadian Therapeutics, Inc. | CASC | Disposition | Stock Option (Right to buy) | 41.7k | $21.06 | $877.5k | | 03/09/2018 |
| 03/09/2018 | Cascadian Therapeutics, Inc. | CASC | Disposition | Stock Option (Right to buy) | 54.2k | $6.90 | $373.8k | | 03/09/2018 |
| 03/09/2018 | Cascadian Therapeutics, Inc. | CASC | Disposition | Stock Option (Right to buy) | 51.2k | $4.64 | $237.6k | | 03/09/2018 |
| 03/09/2018 | Cascadian Therapeutics, Inc. | CASC | Disposition | Stock Option (Right to buy) | 65k | $3.99 | $259.4k | | 03/09/2018 |
| 03/09/2018 | Cascadian Therapeutics, Inc. | CASC | Disposition | Restricted Stock Units | 11.3k | $0.00 | $0 | | 03/09/2018 |
| 03/09/2018 | Cascadian Therapeutics, Inc. | CASC | Disposition | Restricted Stock Units | 14k | $0.00 | $0 | | 03/09/2018 |
| 03/09/2018 | Cascadian Therapeutics, Inc. | CASC | Disposition | Restricted Stock Units | 155.5k | $0.00 | $0 | | 03/09/2018 |
| 03/09/2018 | Cascadian Therapeutics, Inc. | CASC | Disposition | Stock Option (Right to buy) | 8.3k | $41.52 | $346k | | 03/09/2018 |
| 03/09/2018 | Cascadian Therapeutics, Inc. | CASC | Disposition | Stock Option (Right to buy) | 8.3k | $19.92 | $166k | | 03/09/2018 |
| 03/09/2018 | Cascadian Therapeutics, Inc. | CASC | Other | Common Stock | 3.6k | $0.00 | $0 | | 03/09/2018 |
| 02/01/2018 | Cascadian Therapeutics, Inc. | CASC | Grant | Restricted Share Unit (RSU) | 155.5k | $0.00 | $0 | | 02/01/2018 |
| 01/11/2018 | Cascadian Therapeutics, Inc. | CASC | Exercise | Restricted Share Unit (RSU) | 2.8k | $0.00 | $0 | | 01/11/2018 |
| 01/11/2018 | Cascadian Therapeutics, Inc. | CASC | Payment of Exercise | Common Stock | 923 | $3.92 | $3.6k | | 01/11/2018 |
| 05/17/2016 | Cascadian Therapeutics, Inc. | CASC | Grant | Stock Option (right to buy) | 325k | $1.15 | $373.8k | | 05/17/2016 |