| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 10/05/2022 | Global Blood Therapeutics, Inc. | GBT | Disposition | Stock Option (Right to Buy) | 35k | $59.60 | $2.1M | | 10/05/2022 |
| 10/05/2022 | Global Blood Therapeutics, Inc. | GBT | Disposition | Stock Option (Right to Buy) | 38.7k | $44.48 | $1.7M | | 10/05/2022 |
| 10/05/2022 | Global Blood Therapeutics, Inc. | GBT | Disposition | Stock Option (Right to Buy) | 28.6k | $29.87 | $855.1k | | 10/05/2022 |
| 10/05/2022 | Global Blood Therapeutics, Inc. | GBT | Disposition | Common Stock | 26.7k | $0.00 | $0 | | 10/05/2022 |
| 10/05/2022 | Global Blood Therapeutics, Inc. | GBT | Disposition | Restricted Stock Units | 3.1k | $0.00 | $0 | | 10/05/2022 |
| 10/05/2022 | Global Blood Therapeutics, Inc. | GBT | Disposition | Restricted Stock Units | 9.1k | $0.00 | $0 | | 10/05/2022 |
| 10/05/2022 | Global Blood Therapeutics, Inc. | GBT | Disposition | Restricted Stock Units | 13.8k | $0.00 | $0 | | 10/05/2022 |
| 10/05/2022 | Global Blood Therapeutics, Inc. | GBT | Disposition | Restricted Stock Units | 15.5k | $0.00 | $0 | | 10/05/2022 |
| 10/05/2022 | Global Blood Therapeutics, Inc. | GBT | Disposition | Restricted Stock Units | 26.5k | $0.00 | $0 | | 10/05/2022 |
| 10/05/2022 | Global Blood Therapeutics, Inc. | GBT | Disposition | Restricted Stock Units | 42.4k | $0.00 | $0 | | 10/05/2022 |
| 10/05/2022 | Global Blood Therapeutics, Inc. | GBT | Disposition | Stock Option (Right to Buy) | 120k | $14.96 | $1.8M | | 10/05/2022 |
| 10/05/2022 | Global Blood Therapeutics, Inc. | GBT | Disposition | Stock Option (Right to Buy) | 10.3k | $16.40 | $168.9k | | 10/05/2022 |
| 10/05/2022 | Global Blood Therapeutics, Inc. | GBT | Disposition | Stock Option (Right to Buy) | 40k | $48.44 | $1.9M | | 10/05/2022 |
| 10/05/2022 | Global Blood Therapeutics, Inc. | GBT | Disposition | Stock Option (Right to Buy) | 38.5k | $65.82 | $2.5M | | 10/05/2022 |
| 09/27/2022 | Global Blood Therapeutics, Inc. | GBT | Exercise | Stock Option (Right to Buy) | 23.7k | $16.40 | $387.9k | | 09/27/2022 |
| 09/01/2022 | Global Blood Therapeutics, Inc. | GBT | Payment of Exercise | Common Stock | 1.9k | $68.15 | $128.5k | | 09/01/2022 |
| 09/01/2022 | Global Blood Therapeutics, Inc. | GBT | Sale | Common Stock | 31.4k | $68.00 | $2.1M | | 09/01/2022 |
| 09/01/2022 | Global Blood Therapeutics, Inc. | GBT | Exercise | Restricted Stock Units | 2.8k | $0.00 | $0 | | 09/01/2022 |
| 09/01/2022 | Global Blood Therapeutics, Inc. | GBT | Exercise | Restricted Stock Units | 2.2k | $0.00 | $0 | | 09/01/2022 |
| 08/01/2022 | Global Blood Therapeutics, Inc. | GBT | Payment of Exercise | Common Stock | 2.1k | $32.40 | $68.9k | | 08/01/2022 |
| 08/01/2022 | Global Blood Therapeutics, Inc. | GBT | Exercise | Restricted Stock Units | 3.1k | $0.00 | $0 | | 08/01/2022 |
| 08/01/2022 | Global Blood Therapeutics, Inc. | GBT | Exercise | Restricted Stock Units | 3k | $0.00 | $0 | | 08/01/2022 |
| 03/01/2022 | Global Blood Therapeutics, Inc. | GBT | Payment of Exercise | Common Stock | 1.3k | $29.87 | $39.3k | | 03/01/2022 |
| 03/01/2022 | Global Blood Therapeutics, Inc. | GBT | Exercise | Restricted Stock Units | 2.8k | $0.00 | $0 | | 03/01/2022 |
| 03/01/2022 | Global Blood Therapeutics, Inc. | GBT | Grant | Restricted Stock Units | 17.7k | $0.00 | $0 | | 03/01/2022 |
| 03/01/2022 | Global Blood Therapeutics, Inc. | GBT | Grant | Stock Option (Right to buy) | 28.6k | $29.87 | $855.1k | | 03/01/2022 |
| 02/01/2022 | Global Blood Therapeutics, Inc. | GBT | Exercise | Restricted Stock Units | 3.1k | $0.00 | $0 | | 02/01/2022 |
| 02/01/2022 | Global Blood Therapeutics, Inc. | GBT | Exercise | Restricted Stock Units | 3k | $0.00 | $0 | | 02/01/2022 |
| 02/01/2022 | Global Blood Therapeutics, Inc. | GBT | Payment of Exercise | Common Stock | 4.5k | $29.33 | $132.2k | | 02/01/2022 |
| 02/01/2022 | Global Blood Therapeutics, Inc. | GBT | Exercise | Restricted Stock Units | 2.9k | $0.00 | $0 | | 02/01/2022 |
| 09/01/2021 | Global Blood Therapeutics, Inc. | GBT | Exercise | Restricted Stock Units | 2.8k | $0.00 | $0 | | 09/01/2021 |
| 09/01/2021 | Global Blood Therapeutics, Inc. | GBT | Payment of Exercise | Common Stock | 1.4k | $29.85 | $40.9k | | 09/01/2021 |
| 08/01/2021 | Global Blood Therapeutics, Inc. | GBT | Exercise | Restricted Stock Units | 3k | $0.00 | $0 | | 08/01/2021 |
| 08/01/2021 | Global Blood Therapeutics, Inc. | GBT | Payment of Exercise | Common Stock | 4.4k | $27.33 | $119k | | 08/01/2021 |
| 08/01/2021 | Global Blood Therapeutics, Inc. | GBT | Exercise | Restricted Stock Units | 2.9k | $0.00 | $0 | | 08/01/2021 |
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