| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 08/08/2023 | AGIOS PHARMACEUTICALS, INC. | AGIO | Exercise | Restricted stock units | 22.7k | $0.00 | $0 | | 08/08/2023 |
| 08/08/2023 | AGIOS PHARMACEUTICALS, INC. | AGIO | Sale | Common stock | 10.2k | $25.48 | $259.3k | | 08/08/2023 |
| 06/30/2023 | AGIOS PHARMACEUTICALS, INC. | AGIO | Sale | Common stock | 11.4k | $28.36 | $324.7k | | 06/28/2023 |
| 06/28/2023 | AGIOS PHARMACEUTICALS, INC. | AGIO | Exercise | Performance share units | 25.5k | $0.00 | $0 | | 06/28/2023 |
| 07/21/2021 | ALEXION PHARMACEUTICALS, INC. | ALXN | Disposition | Common Stock, par value $.0001 per share | 150.8k | $0.00 | $0 | | 07/21/2021 |
| 07/21/2021 | ALEXION PHARMACEUTICALS, INC. | ALXN | Disposition | Option to Purchase Common Stock | 21.8k | $100.14 | $2.2M | | 07/21/2021 |
| 07/14/2021 | ALEXION PHARMACEUTICALS, INC. | ALXN | Grant | Common Stock, par value $.0001 per share | 30.6k | $0.00 | $0 | | 07/14/2021 |
| 07/14/2021 | ALEXION PHARMACEUTICALS, INC. | ALXN | Grant | Common Stock, par value $.0001 per share | 29.5k | $0.00 | $0 | | 07/14/2021 |
| 06/08/2021 | ALEXION PHARMACEUTICALS, INC. | ALXN | Payment of Exercise | Common Stock, par value $.0001 per share | 1.1k | $177.00 | $192.2k | | 06/08/2021 |
| 02/28/2021 | ALEXION PHARMACEUTICALS, INC. | ALXN | Grant | Common Stock, par value $.0001 per share | 24.5k | $0.00 | $0 | | 02/28/2021 |
| 12/16/2020 | ALEXION PHARMACEUTICALS, INC. | ALXN | Payment of Exercise | Common Stock, par value $.0001 per share | 3.3k | $157.96 | $515.1k | | 12/16/2020 |
| 12/16/2020 | ALEXION PHARMACEUTICALS, INC. | ALXN | Payment of Exercise | Common Stock, par value $.0001 per share | 18.1k | $157.96 | $2.9M | | 12/16/2020 |
| 12/16/2020 | ALEXION PHARMACEUTICALS, INC. | ALXN | Grant | Common Stock, par value $.0001 per share | 40.7k | $0.00 | $0 | | 12/16/2020 |
| 06/08/2020 | ALEXION PHARMACEUTICALS, INC. | ALXN | Payment of Exercise | Common Stock, par value $.0001 per share | 1.6k | $114.61 | $188.2k | | 06/08/2020 |
| 03/02/2020 | ALEXION PHARMACEUTICALS, INC. | ALXN | Payment of Exercise | Common Stock, par value $.0001 per share | 1.4k | $90.54 | $126.8k | | 02/28/2020 |
| 02/28/2020 | ALEXION PHARMACEUTICALS, INC. | ALXN | Grant | Common Stock, par value $.0001 per share | 10.9k | $0.00 | $0 | | 02/28/2020 |
| 02/07/2020 | ALEXION PHARMACEUTICALS, INC. | ALXN | Payment of Exercise | Common Stock, par value $.0001 per share | 1.6k | $102.97 | $164.1k | | 02/07/2020 |
| 06/07/2019 | ALEXION PHARMACEUTICALS, INC. | ALXN | Payment of Exercise | Common Stock, par value $.0001 per share | 1.6k | $118.61 | $194.9k | | 06/07/2019 |
| 02/28/2019 | ALEXION PHARMACEUTICALS, INC. | ALXN | Grant | Common Stock, par value $.0001 per share | 9.4k | $0.00 | $0 | | 02/28/2019 |
| 02/28/2019 | ALEXION PHARMACEUTICALS, INC. | ALXN | Payment of Exercise | Common Stock, par value $.0001 per share | 670 | $132.93 | $89.1k | | 02/28/2019 |
| 02/07/2019 | ALEXION PHARMACEUTICALS, INC. | ALXN | Payment of Exercise | Common Stock, par value $.0001 per share | 1.6k | $119.57 | $190.8k | | 02/07/2019 |
| 06/08/2018 | ALEXION PHARMACEUTICALS, INC. | ALXN | Sale | Common Stock, par value $.0001 per share | 1.6k | $118.53 | $195k | | 06/08/2018 |
| 02/28/2018 | ALEXION PHARMACEUTICALS, INC. | ALXN | Grant | Common Stock, par value $.0001 per share | 8.9k | $0.00 | $0 | | 02/28/2018 |
| 02/08/2018 | ALEXION PHARMACEUTICALS, INC. | ALXN | Sale | Common Stock, par value $.0001 per share | 1.7k | $116.31 | $192k | | 02/06/2018 |
| 02/06/2018 | ALEXION PHARMACEUTICALS, INC. | ALXN | Grant | Common Stock, par value $.0001 per share | 15.9k | $0.00 | $0 | | 02/06/2018 |
| 06/03/2016 | Baxalta Inc | BXLT | Grant | | 2.9k | $0.00 | $0 | | 06/03/2016 |
| 06/03/2016 | Baxalta Inc | BXLT | Disposition | | 70k | $0.00 | $0 | | 06/03/2016 |
| 06/03/2016 | Baxalta Inc | BXLT | Disposition | Stock Option (Right to Buy) | 37k | $23.15 | $856.6k | | 06/03/2016 |
| 06/03/2016 | Baxalta Inc | BXLT | Disposition | Stock Option (Right to Buy) | 25.8k | $32.42 | $835.6k | | 06/03/2016 |
| 06/03/2016 | Baxalta Inc | BXLT | Disposition | Stock Option (Right to Buy) | 31.4k | $31.86 | $999.6k | | 06/03/2016 |
| 06/03/2016 | Baxalta Inc | BXLT | Disposition | Stock Option (Right to Buy) | 88.2k | $32.04 | $2.8M | | 06/03/2016 |
| 06/03/2016 | Baxalta Inc | BXLT | Disposition | Stock Option (Right to Buy) | 35.2k | $31.50 | $1.1M | | 06/03/2016 |
| 06/03/2016 | Baxalta Inc | BXLT | Disposition | Stock Option (Right to Buy) | 265.2k | $31.50 | $8.4M | | 06/03/2016 |
| 03/07/2016 | Baxalta Inc | BXLT | Payment of Exercise | Common Stock, par value $0.01 per share | 267 | $39.74 | $10.6k | | 03/07/2016 |
| 03/04/2016 | Baxalta Inc | BXLT | Payment of Exercise | Common Stock, par value $0.01 per share | 303 | $39.47 | $12k | | 03/03/2016 |
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