| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 12/20/2022 | Design Therapeutics, Inc. | DSGN | Purchase | Common Stock | 6.3k | $8.38 | $52.8k | | 12/19/2022 |
| 12/19/2022 | Design Therapeutics, Inc. | DSGN | Purchase | Common Stock | 1.2k | $8.47 | $9.7k | | 12/19/2022 |
| 02/01/2022 | Design Therapeutics, Inc. | DSGN | Grant | Stock Option (right to buy) | 475k | $12.77 | $6.1M | | 02/01/2022 |
| 05/20/2020 | ABEONA THERAPEUTICS INC. | ABEO | Grant | Employee Stock Option (right to buy) | 72.3k | $3.20 | $231.3k | | 05/20/2020 |
| 05/20/2020 | ABEONA THERAPEUTICS INC. | ABEO | Grant | Common Stock | 100k | $0.00 | $0 | | 05/20/2020 |
| 03/16/2020 | ABEONA THERAPEUTICS INC. | ABEO | Grant | | 127.7k | $1.45 | $185.2k | | 03/16/2020 |
| 04/09/2019 | ABEONA THERAPEUTICS INC. | ABEO | Grant | Employee Stock Option (right to buy) | 100k | $7.24 | $724k | | 04/09/2019 |
| 02/11/2019 | ABEONA THERAPEUTICS INC. | ABEO | Grant | Employee Stock Option (right to buy) | 110k | $6.70 | $737k | | 01/31/2019 |
| 01/31/2019 | ABEONA THERAPEUTICS INC. | ABEO | Grant | Employee Stock Option (right to buy) | 60k | $6.59 | $395.4k | | 01/31/2019 |
| 05/15/2018 | AveXis, Inc. | AVXS | Disposition | Stock Option (Right to Buy) | 7.8k | $69.25 | $537k | | 05/15/2018 |
| 05/15/2018 | AveXis, Inc. | AVXS | Disposition | Stock Option (Right to Buy) | 2.9k | $133.80 | $388.7k | | 05/15/2018 |
| 05/15/2018 | AveXis, Inc. | AVXS | Disposition | Common Stock | 1.1k | $0.00 | $0 | | 05/15/2018 |
| 03/13/2018 | AveXis, Inc. | AVXS | Grant | Stock Option (Right to Buy) | 2.9k | $133.80 | $388.7k | | 03/13/2018 |
| 03/13/2018 | AveXis, Inc. | AVXS | Grant | Common Stock | 1.1k | $0.00 | $0 | | 03/13/2018 |
| 05/30/2017 | AveXis, Inc. | AVXS | Grant | Stock Option (Right to Buy) | 5.3k | $69.25 | $367.1k | | 05/30/2017 |
| 05/30/2017 | AveXis, Inc. | AVXS | Grant | Stock Option (Right to Buy) | 2.5k | $69.25 | $169.9k | | 05/30/2017 |
| 12/13/2013 | AVANIR PHARMACEUTICALS, INC. | AVNR | Grant | Stock Option (right to buy) | 47.5k | $2.84 | $134.9k | | 12/13/2013 |
| 09/18/2013 | AVANIR PHARMACEUTICALS, INC. | AVNR | Sale | Common Stock | 21.1k | $4.22 | $89k | | 09/18/2013 |
| 09/18/2013 | AVANIR PHARMACEUTICALS, INC. | AVNR | Exercise | Stock Option (right to buy) | 21.1k | $1.85 | $39k | | 09/18/2013 |
| 12/17/2012 | AVANIR PHARMACEUTICALS, INC. | AVNR | Grant | Common Stock | 49.1k | $0.00 | $0 | | 12/17/2012 |
| 12/17/2012 | AVANIR PHARMACEUTICALS, INC. | AVNR | Grant | Common Stock | 34.9k | $0.00 | $0 | | 12/17/2012 |
| 12/17/2012 | AVANIR PHARMACEUTICALS, INC. | AVNR | Grant | Stock Option (right to buy) | 75k | $2.59 | $194.2k | | 12/17/2012 |
| 05/10/2012 | AVANIR PHARMACEUTICALS, INC. | AVNR | Purchase | Common Stock | 2.7k | $2.96 | $8k | | 05/10/2012 |