| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 06/02/2023 | Aclaris Therapeutics, Inc. | ACRS | Exercise | Restricted Stock Units | 4.5k | $0.00 | $0 | | 06/01/2023 |
| 06/01/2023 | Aclaris Therapeutics, Inc. | ACRS | Grant | Stock Option (Right to Buy) | 15.8k | $8.70 | $137k | | 06/01/2023 |
| 06/01/2023 | Aclaris Therapeutics, Inc. | ACRS | Grant | Restricted Stock Units | 4.7k | $0.00 | $0 | | 06/01/2023 |
| 11/14/2022 | Aclaris Therapeutics, Inc. | ACRS | Sale | Common Stock | 1.4k | $17.08 | $23.4k | By Aisling Capital IV LP | 11/10/2022 |
| 11/11/2022 | Aclaris Therapeutics, Inc. | ACRS | Sale | Common Stock | 41.2k | $17.06 | $702.2k | By Aisling Capital IV LP | 11/10/2022 |
| 11/10/2022 | Aclaris Therapeutics, Inc. | ACRS | Sale | Common Stock | 11.4k | $17.02 | $194k | By Aisling Capital IV LP | 11/10/2022 |
| 10/26/2022 | Aclaris Therapeutics, Inc. | ACRS | Sale | Common Stock | 14.5k | $17.01 | $247.3k | By Aisling Capital IV LP | 10/24/2022 |
| 10/25/2022 | Aclaris Therapeutics, Inc. | ACRS | Sale | Common Stock | 12k | $17.02 | $204.5k | By Aisling Capital IV LP | 10/24/2022 |
| 10/24/2022 | Aclaris Therapeutics, Inc. | ACRS | Sale | Common Stock | 14.6k | $17.01 | $248.6k | By Aisling Capital IV LP | 10/24/2022 |
| 10/07/2022 | Aclaris Therapeutics, Inc. | ACRS | Sale | Common Stock | 7.3k | $16.16 | $118.3k | By Aisling Capital IV LP | 10/07/2022 |
| 10/06/2022 | Aclaris Therapeutics, Inc. | ACRS | Sale | Common Stock | 37.8k | $16.54 | $625.7k | By Aisling Capital IV LP | 10/04/2022 |
| 10/04/2022 | Aclaris Therapeutics, Inc. | ACRS | Sale | Common Stock | 7.7k | $16.01 | $123.3k | By Aisling Capital IV LP | 10/04/2022 |
| 06/17/2022 | Aclaris Therapeutics, Inc. | ACRS | Sale | Common Stock | 19.6k | $15.14 | $296.3k | | 06/17/2022 |
| 06/15/2022 | Monte Rosa Therapeutics, Inc. | | Grant | Stock Option (Right to Buy) | 15k | $7.66 | $114.9k | | 06/15/2022 |
| 06/03/2022 | Aclaris Therapeutics, Inc. | ACRS | Exercise | Restricted Stock Units | 3.4k | $0.00 | $0 | | 06/02/2022 |
| 06/02/2022 | Aclaris Therapeutics, Inc. | ACRS | Grant | Stock Option (Right to Buy) | 15.8k | $14.48 | $228.1k | | 06/02/2022 |
| 06/02/2022 | Aclaris Therapeutics, Inc. | ACRS | Grant | Restricted Stock Units | 4.5k | $0.00 | $0 | | 06/02/2022 |
| 06/23/2021 | Monte Rosa Therapeutics, Inc. | | Grant | Stock Option (Right to Buy) | 47.1k | $19.00 | $895.5k | | 06/23/2021 |
| 06/03/2021 | Aclaris Therapeutics, Inc. | ACRS | Grant | Stock Option (Right to Buy) | 12.2k | $21.90 | $268.3k | | 06/03/2021 |
| 06/03/2021 | Aclaris Therapeutics, Inc. | ACRS | Grant | Restricted Stock Units | 3.4k | $0.00 | $0 | | 06/03/2021 |
| 06/06/2020 | Aclaris Therapeutics, Inc. | ACRS | Exercise | Restricted Stock Units | 7.3k | $0.00 | $0 | | 06/04/2020 |
| 06/04/2020 | Aclaris Therapeutics, Inc. | ACRS | Grant | Option Grant (right to buy) | 16.5k | $1.41 | $23.3k | | 06/04/2020 |
| 03/02/2020 | Aclaris Therapeutics, Inc. | ACRS | Exercise | Restricted stock units | 8.9k | $0.00 | $0 | | 03/02/2020 |
| 03/02/2020 | Aclaris Therapeutics, Inc. | ACRS | Grant | Restricted stock units | 8.9k | $0.00 | $0 | | 03/02/2020 |
| 06/06/2019 | Aclaris Therapeutics, Inc. | ACRS | Grant | Restricted Stock Units | 7.3k | $0.00 | $0 | | 06/06/2019 |
| 06/07/2018 | Aclaris Therapeutics, Inc. | ACRS | Grant | Stock Option (right to buy) | 8k | $18.35 | $146.8k | | 06/07/2018 |
| 08/16/2017 | Aclaris Therapeutics, Inc. | ACRS | Purchase | Common Stock | 108.6k | $23.02 | $2.5M | By Aisling Capital IV LP | 08/16/2017 |
| 08/09/2017 | Aclaris Therapeutics, Inc. | ACRS | Grant | Stock Option (right to buy) | 16k | $26.97 | $431.5k | | 08/09/2017 |