| Date | Name | Title | Type | Security | Shares | Price | Value | Ownership | Reported |
| 01/17/2023 | FLETCHER R JOHN | Director | Grant | Common Stock, $0.0001 par value | 4.4k | $0.00 | $0 | | 01/17/2023 |
| 01/17/2023 | Harris Geoffrey E. | Director | Grant | Common Stock, $0.0001 par value | 5.7k | $0.00 | $0 | | 01/17/2023 |
| 01/17/2023 | Horobin Joanna | Director | Grant | Common Stock, $0.0001 par value | 7.5k | $0.00 | $0 | | 01/17/2023 |
| 01/17/2023 | Hansen Paul R. | Director | Grant | Common Stock, $0.0001 par value | 4k | $0.00 | $0 | | 01/17/2023 |
| 11/18/2022 | Harris Geoffrey E. | Director | Sale | Common Stock, $0.0001 par value | 99 | $1.34 | $132.7 | | 11/18/2022 |
| 11/18/2022 | Harris Geoffrey E. | Director | Sale | Common Stock, $0.0001 par value | 666 | $1.33 | $888.4 | | 11/18/2022 |
| 07/18/2022 | Harris Geoffrey E. | Director | Grant | Common Stock, $0.0001 par value | 6.1k | $0.00 | $0 | | 07/18/2022 |
| 07/18/2022 | Horobin Joanna | Director | Grant | Common Stock, $0.0001 par value | 8.1k | $0.00 | $0 | | 07/18/2022 |
| 07/18/2022 | FLETCHER R JOHN | Director | Grant | Common Stock, $0.0001 par value | 4.7k | $0.00 | $0 | | 07/18/2022 |
| 07/18/2022 | Hansen Paul R. | Director | Grant | Common Stock, $0.0001 par value | 4.3k | $0.00 | $0 | | 07/18/2022 |
| 04/18/2022 | Hansen Paul R. | Director | Grant | Common Stock, $0.0001 par value | 3.6k | $0.00 | $0 | | 04/18/2022 |
| 04/18/2022 | Boehm Marcus | Director | Grant | Common Stock, $0.0001 par value | 7.3k | $0.00 | $0 | | 04/18/2022 |
| 04/18/2022 | FLETCHER R JOHN | Director | Grant | Common Stock, $0.0001 par value | 3.9k | $0.00 | $0 | | 04/18/2022 |
| 04/18/2022 | Harris Geoffrey E. | Director | Grant | Common Stock, $0.0001 par value | 5.2k | $0.00 | $0 | | 04/18/2022 |
| 04/18/2022 | Horobin Joanna | Director | Grant | Common Stock, $0.0001 par value | 6.8k | $0.00 | $0 | | 04/18/2022 |
| 03/30/2022 | Boehm Marcus | Director | Grant | Common Stock, $0.0001 par value | 43.5k | $0.00 | $0 | | 03/30/2022 |
| 03/30/2022 | McLeod Howard | Director | Grant | Common Stock, $0.0001 par value | 43.5k | $0.00 | $0 | | 03/30/2022 |
| 03/30/2022 | Horobin Joanna | Director | Grant | Common Stock, $0.0001 par value | 43.5k | $0.00 | $0 | | 03/30/2022 |
| 03/30/2022 | Harris Geoffrey E. | Director | Grant | Common Stock, $0.0001 par value | 43.5k | $0.00 | $0 | | 03/30/2022 |
| 03/30/2022 | FLETCHER R JOHN | Director | Grant | Common Stock, $0.0001 par value | 24.8k | $0.00 | $0 | | 03/30/2022 |
| 03/30/2022 | FLETCHER R JOHN | Director | Grant | Common Stock, $0.0001 par value | 43.5k | $0.00 | $0 | | 03/30/2022 |
| 03/30/2022 | Yeh Yung-Ping | Director | Grant | Common Stock, $0.0001 par value | 43.5k | $0.00 | $0 | | 03/30/2022 |
| 03/30/2022 | Hansen Paul R. | Director | Grant | Common Stock, $0.0001 par value | 43.5k | $0.00 | $0 | | 03/30/2022 |
| 03/15/2022 | Fremeau Robert Thomas Jr. | Chief Scientific Officer | Grant | Stock option (right to buy) | 75k | $1.00 | $75k | | 03/15/2022 |
| 03/15/2022 | LaFrence Andrew D.C. | CFO | Grant | Stock option (right to buy) | 110k | $1.00 | $110k | | 03/15/2022 |
| 03/15/2022 | ROBERTS JOHN A | CEO | Grant | Stock option (right to buy) | 150k | $1.00 | $150k | | 03/15/2022 |
| 01/18/2022 | FLETCHER R JOHN | Director | Grant | Common Stock, $0.0001 par value | 3.7k | $1.31 | $4.9k | | 01/18/2022 |
| 01/18/2022 | Horobin Joanna | Director | Grant | Common Stock, $0.0001 par value | 5.3k | $1.31 | $7k | | 01/18/2022 |
| 01/18/2022 | Harris Geoffrey E. | Director | Grant | Common Stock, $0.0001 par value | 4.1k | $1.31 | $5.3k | | 01/18/2022 |
| 01/18/2022 | Boehm Marcus | Director | Grant | Common Stock, $0.0001 par value | 5.7k | $1.31 | $7.5k | | 01/18/2022 |
| 01/18/2022 | Hansen Paul R. | Director | Grant | Common Stock, $0.0001 par value | 2.9k | $1.31 | $3.7k | | 01/18/2022 |
| 12/06/2021 | Boehm Marcus | Director | Purchase | Common Stock, $0.0001 par value | 5k | $1.69 | $8.4k | By Trust | 12/06/2021 |
| 11/24/2021 | ROBERTS JOHN A | CEO | Purchase | Common Stock, $0.0001 par value | 5k | $2.02 | $10.1k | | 11/24/2021 |
| 11/23/2021 | LaFrence Andrew D.C. | CFO | Purchase | Common Stock, $0.0001 par value | 5k | $2.00 | $10k | | 11/23/2021 |
| 11/23/2021 | LaFrence Andrew D.C. | CFO | Purchase | Common Stock, $0.0001 par value | 5k | $2.00 | $10k | | 11/23/2021 |
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