| Date | Name | Title | Type | Security | Shares | Price | Value | Ownership | Reported |
| 04/28/2023 | FEIGHAN EDWARD F | Director | Purchase | Common Stock | 30k | $0.20 | $6k | | 04/19/2023 |
| 04/26/2023 | FEIGHAN EDWARD F | Director | Purchase | Common Stock | 2k | $0.20 | $400 | | 04/19/2023 |
| 04/25/2023 | FEIGHAN EDWARD F | Director | Purchase | Common Stock | 2k | $0.20 | $390.2 | | 04/19/2023 |
| 04/21/2023 | FEIGHAN EDWARD F | Director | Purchase | Common Stock | 10k | $0.20 | $2k | | 04/19/2023 |
| 04/21/2023 | FEIGHAN EDWARD F | Director | Purchase | Common Stock | 5k | $0.20 | $993.5 | | 04/19/2023 |
| 04/19/2023 | FEIGHAN EDWARD F | Director | Purchase | Common Stock | 1000 | $0.18 | $184.5 | | 04/19/2023 |
| 05/10/2022 | LoConti Joseph E. | 10% Owner | Grant | Warrant | 6.7M | $0.60 | $4M | By Tower IV LLC | 05/10/2022 |
| 05/10/2022 | LoConti Joseph E. | 10% Owner | Purchase | Common Stock, par value $0.001 per share | 6.7M | $0.15 | $1M | By Tower IV LLC | 05/10/2022 |
| 12/10/2021 | Zipp Brandon Joel | Chief Science Officer | Disposition | Stock Option (Right to Buy) | 7.5k | $4.40 | $33k | | 12/10/2021 |
| 12/10/2021 | Zipp Brandon Joel | Chief Science Officer | Disposition | Stock Option (Right to Buy) | 15k | $4.20 | $63k | | 12/10/2021 |
| 12/10/2021 | Zipp Brandon Joel | Chief Science Officer | Disposition | Stock Option (Right to Buy) | 20k | $3.40 | $68k | | 12/10/2021 |
| 12/10/2021 | Zipp Brandon Joel | Chief Science Officer | Disposition | Stock Option (Right to Buy) | 20k | $2.10 | $42k | | 12/10/2021 |
| 12/10/2021 | Zipp Brandon Joel | Chief Science Officer | Disposition | Stock Option (Right to Buy) | 75k | $1.81 | $135.8k | | 12/10/2021 |
| 12/10/2021 | Zipp Brandon Joel | Chief Science Officer | Grant | Stock Option (Right to Buy) | 127.5k | $0.28 | $35.3k | | 12/10/2021 |
| 12/10/2021 | Zipp Brandon Joel | Chief Science Officer | Grant | Stock Option (Right to Buy) | 22.5k | $0.28 | $6.2k | | 12/10/2021 |
| 12/10/2021 | Celeste Richard F | Director | Grant | Stock Option (Right to Buy) | 250k | $0.28 | $69.2k | | 12/10/2021 |
| 12/10/2021 | FEIGHAN EDWARD F | Director | Grant | Stock Option (Right to Buy) | 250k | $0.28 | $69.2k | | 12/10/2021 |
| 12/10/2021 | MCKILLIGAN RICHARD | CFO | Grant | Stock Option (Right to Buy) | 114.8k | $0.28 | $31.8k | | 12/10/2021 |
| 12/10/2021 | MCKILLIGAN RICHARD | CFO | Grant | Stock Option (Right to Buy) | 35.2k | $0.28 | $9.8k | | 12/10/2021 |
| 12/10/2021 | Cavanaugh Michael R. | CEO | Grant | Stock Option (Right to Buy) | 350k | $0.28 | $97k | | 12/10/2021 |
| 12/10/2021 | MCKILLIGAN RICHARD | CFO | Disposition | Stock Option (Right to Buy) | 10k | $2.70 | $27k | | 12/10/2021 |
| 12/10/2021 | MCKILLIGAN RICHARD | CFO | Disposition | Stock Option (Right to Buy) | 20k | $3.40 | $68k | | 12/10/2021 |
| 12/10/2021 | MCKILLIGAN RICHARD | CFO | Disposition | Stock Option (Right to Buy) | 20k | $2.10 | $42k | | 12/10/2021 |
| 12/10/2021 | MCKILLIGAN RICHARD | CFO | Disposition | Stock Option (Right to Buy) | 75k | $1.81 | $135.8k | | 12/10/2021 |
| 12/10/2021 | Zipp Brandon Joel | Chief Science Officer | Disposition | Stock Option (Right to Buy) | 2.5k | $4.20 | $10.5k | | 12/10/2021 |
| 07/29/2021 | LoConti Joseph E. | 10% Owner | Purchase | Common Stock, par value $0.001 per share | 1000 | $0.20 | $200 | By Paragon Small Cap Fund I, LP | 05/29/2019 |
| 07/20/2021 | LoConti Joseph E. | 10% Owner | Purchase | Common Stock, par value $0.001 per share | 13k | $0.20 | $2.6k | By Paragon Small Cap Fund I, LP | 05/29/2019 |
| 07/19/2021 | LoConti Joseph E. | 10% Owner | Purchase | Common Stock, par value $0.001 per share | 40k | $0.16 | $6.4k | By Paragon Small Cap Fund I, LP | 05/29/2019 |
| 07/19/2021 | LoConti Joseph E. | 10% Owner | Purchase | Common Stock, par value $0.001 per share | 67k | $0.19 | $12.7k | By Paragon Small Cap Fund I, LP | 05/29/2019 |
| 07/19/2021 | LoConti Joseph E. | 10% Owner | Purchase | Common Stock, par value $0.001 per share | 20k | $0.20 | $4k | By Paragon Small Cap Fund I, LP | 05/29/2019 |
| 07/09/2021 | LoConti Joseph E. | 10% Owner | Purchase | Common Stock, par value $0.001 per share | 20k | $0.19 | $3.8k | By Paragon Small Cap Fund I, LP | 05/29/2019 |
| 05/11/2021 | LoConti Joseph E. | 10% Owner | Purchase | Common Stock, par value $0.001 per share | 10k | $0.17 | $1.7k | By Paragon Small Cap Fund I, LP | 05/29/2019 |
| 05/11/2021 | LoConti Joseph E. | 10% Owner | Purchase | Common Stock, par value $0.001 per share | 10k | $0.18 | $1.8k | By Paragon Small Cap Fund I, LP | 05/29/2019 |
| 02/05/2021 | Zipp Brandon Joel | Chief Science Officer | Purchase | Common Stock, par value $0.001 per share | 19.1k | $0.19 | $3.6k | | 02/04/2021 |
| 02/04/2021 | Zipp Brandon Joel | Chief Science Officer | Purchase | Common Stock, par value $0.001 per share | 30.9k | $0.17 | $5.3k | | 02/04/2021 |
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