| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 05/04/2023 | RAPID MICRO BIOSYSTEMS, INC. | RPID | Grant | Stock Option (Right to Buy) | 25k | $0.87 | $21.8k | | 05/04/2023 |
| 05/23/2022 | RAPID MICRO BIOSYSTEMS, INC. | RPID | Grant | Stock Option (Right to Buy) | 12.5k | $4.50 | $56.2k | | 05/23/2022 |
| 10/05/2021 | Strongbridge Biopharma plc | SBBP | Disposition | Ordinary Shares | 234.2k | $0.00 | $0 | | 10/05/2021 |
| 10/05/2021 | Strongbridge Biopharma plc | SBBP | Disposition | Stock Option (Right to Buy) | 544.9k | $0.00 | $0 | | 10/05/2021 |
| 10/01/2021 | Strongbridge Biopharma plc | SBBP | Payment of Exercise | Ordinary Shares | 64.8k | $2.06 | $133.5k | | 10/01/2021 |
| 09/09/2021 | RAPID MICRO BIOSYSTEMS, INC. | RPID | Exercise (in-the-money or at-the-money) | Series A1 Warrant (right to buy) | 82k | $0.05 | $4.1k | Held by Quaker Bioventures II, L.P. | 09/09/2021 |
| 09/09/2021 | RAPID MICRO BIOSYSTEMS, INC. | RPID | Exercise (in-the-money or at-the-money) | Series B1 Warrant (right to buy) | 12.9k | $0.05 | $645.2 | Held by Quaker Bioventures II, L.P. | 09/09/2021 |
| 09/03/2021 | Strongbridge Biopharma plc | SBBP | Payment of Exercise | Ordinary Shares | 17.1k | $2.24 | $38.3k | | 09/03/2021 |
| 07/19/2021 | RAPID MICRO BIOSYSTEMS, INC. | RPID | Conversion | Class A Common Stock | 1.3M | $0.00 | $0 | Held by Quaker Bioventures II, L.P. | 07/19/2021 |
| 07/19/2021 | RAPID MICRO BIOSYSTEMS, INC. | RPID | Conversion | Series A1 Preferred Stock | 4.6M | $0.00 | $0 | Held by Quaker Bioventures II, L.P. | 07/19/2021 |
| 07/19/2021 | RAPID MICRO BIOSYSTEMS, INC. | RPID | Conversion | Series B1 Preferred Stock | 1.1M | $0.00 | $0 | Held by Quaker Bioventures II, L.P. | 07/19/2021 |
| 07/19/2021 | RAPID MICRO BIOSYSTEMS, INC. | RPID | Conversion | Series C1 Preferred Stock | 820.7k | $0.00 | $0 | Held by Quaker Bioventures II, L.P. | 07/19/2021 |
| 07/19/2021 | RAPID MICRO BIOSYSTEMS, INC. | RPID | Conversion | Series A1 Warrant | 410.1k | $0.01 | $4.1k | Held by Quaker Bioventures II, L.P. | 07/19/2021 |
| 07/19/2021 | RAPID MICRO BIOSYSTEMS, INC. | RPID | Conversion | Common Stock Warrant | 82k | $0.05 | $4.1k | Held by Quaker Bioventures II, L.P. | 07/19/2021 |
| 07/19/2021 | RAPID MICRO BIOSYSTEMS, INC. | RPID | Conversion | Series B1 Warrant | 64.5k | $0.01 | $645.2 | Held by Quaker Bioventures II, L.P. | 07/19/2021 |
| 07/19/2021 | RAPID MICRO BIOSYSTEMS, INC. | RPID | Conversion | Common Stock Warrant | 12.9k | $0.05 | $645.2 | Held by Quaker Bioventures II, L.P. | 07/19/2021 |
| 07/14/2021 | RAPID MICRO BIOSYSTEMS, INC. | RPID | Grant | Stock Option (Right to Buy) | 25k | $20.00 | $500k | | 07/14/2021 |
| 05/17/2021 | Strongbridge Biopharma plc | SBBP | Payment of Exercise | Ordinary Shares | 11.4k | $2.28 | $26k | | 05/17/2021 |
| 03/03/2021 | Strongbridge Biopharma plc | SBBP | Grant | Ordinary Shares | 80k | $0.00 | $0 | | 03/03/2021 |
| 01/07/2021 | Strongbridge Biopharma plc | SBBP | Grant | Ordinary Shares | 147.5k | $0.00 | $0 | | 01/07/2021 |
| 01/27/2020 | Strongbridge Biopharma plc | SBBP | Grant | Employee Stock Option (right to buy) | 200k | $2.98 | $596k | | 01/27/2020 |
| 09/03/2019 | Strongbridge Biopharma plc | SBBP | Grant | Ordinary Shares | 60k | $0.00 | $0 | | 09/03/2019 |
| 09/03/2019 | Strongbridge Biopharma plc | SBBP | Grant | Employee Stock Option (right to buy) | 215k | $2.57 | $552.6k | | 09/03/2019 |
| 05/15/2019 | Strongbridge Biopharma plc | SBBP | Grant | Ordinary Shares | 40k | $0.00 | $0 | | 05/15/2019 |
| 05/15/2018 | Strongbridge Biopharma plc | SBBP | Grant | Stock Options (Right to Buy) | 40k | $7.75 | $310k | | 05/15/2018 |
| 06/11/2015 | Celator Pharmaceuticals Inc | CPXX | Grant | Stock Option (Right to Buy) | 14k | $2.60 | $36.4k | | 06/11/2015 |
| 06/12/2014 | Celator Pharmaceuticals Inc | CPXX | Grant | Stock Option (Right to Buy) | 14k | $2.80 | $39.2k | | 06/12/2014 |
| 10/31/2013 | INSMED Inc | INSM | Exercise | Restricted Stock Units | 9k | $0.00 | $0 | | 10/31/2013 |
| 04/24/2013 | NUPATHE INC. | PATH | Grant | Common Stock | 13.5k | $0.00 | $0 | | 04/24/2013 |
| 03/03/2011 | NUPATHE INC. | PATH | Grant | Stock Option (Right to Buy) | 6k | $7.75 | $46.6k | | 03/03/2011 |