| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 02/08/2023 | Zynerba Pharmaceuticals, Inc. | ZYNE | Payment of Exercise | Common Stock | 10k | $0.60 | $5.9k | | 02/07/2023 |
| 02/07/2023 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Common Stock | 36k | $0.00 | $0 | | 02/07/2023 |
| 01/24/2023 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Common Stock | 170k | $0.00 | $0 | | 01/23/2023 |
| 01/23/2023 | Zynerba Pharmaceuticals, Inc. | ZYNE | Sale | Common Stock | 24.7k | $0.60 | $14.7k | | 01/23/2023 |
| 07/19/2022 | Zynerba Pharmaceuticals, Inc. | ZYNE | Sale | Common Stock | 8.3k | $1.10 | $9.1k | | 07/18/2022 |
| 07/18/2022 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Common Stock | 30k | $0.00 | $0 | | 07/18/2022 |
| 01/26/2022 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Common Stock | 85k | $0.00 | $0 | | 01/26/2022 |
| 01/26/2022 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Stock Option (right to buy) | 125k | $2.41 | $301.2k | | 01/26/2022 |
| 01/21/2021 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Common Stock | 75k | $0.00 | $0 | | 01/21/2021 |
| 01/21/2021 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Stock Option (right to buy) | 110k | $3.58 | $393.8k | | 01/21/2021 |
| 01/30/2020 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Stock Option (right to buy) | 120k | $5.05 | $606k | | 01/30/2020 |
| 01/24/2019 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | | 3.6k | $0.00 | $0 | | 01/24/2019 |
| 01/24/2019 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Stock Option (right to buy) | 120k | $3.65 | $438k | | 01/24/2019 |
| 08/06/2018 | Zynerba Pharmaceuticals, Inc. | ZYNE | Purchase | Common Stock | 3.8k | $5.79 | $22k | | 08/06/2018 |
| 01/11/2018 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Stock Option (right to buy) | 43.9k | $11.71 | $514.3k | | 01/11/2018 |
| 01/25/2017 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Stock Option (right to buy) | 75k | $18.22 | $1.4M | | 01/25/2017 |