| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 02/23/2023 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Grant | Director Stock Option (Right to Buy) | 6.3k | $38.60 | $242.9k | | 02/23/2023 |
| 02/23/2023 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Grant | Restricted Stock Units | 3.9k | $0.00 | $0 | | 02/23/2023 |
| 02/22/2023 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Disposition | Restricted Stock Units | 3.9k | $0.00 | $0 | | 02/22/2023 |
| 02/22/2023 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Grant | Common Stock | 3.9k | $0.00 | $0 | | 02/22/2023 |
| 02/22/2022 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Grant | Restricted Stock Units | 3.9k | $0.00 | $0 | | 02/22/2022 |
| 02/22/2022 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Grant | Director Stock Option (Right to Buy) | 6.8k | $32.20 | $220.5k | | 02/22/2022 |
| 02/19/2022 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Grant | Common Stock | 4.2k | $0.00 | $0 | | 02/19/2022 |
| 02/19/2022 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Disposition | Restricted Stock Units | 4.2k | $0.00 | $0 | | 02/19/2022 |
| 08/11/2021 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Exercise | Director Stock Option (Right to Buy) | 15k | $12.98 | $194.7k | | 08/11/2021 |
| 02/19/2021 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Grant | Director Stock Option (Right to Buy) | 7.4k | $29.61 | $218.1k | | 02/19/2021 |
| 02/19/2021 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Grant | Restricted Stock Units | 4.2k | $0.00 | $0 | | 02/19/2021 |
| 02/21/2020 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Grant | Director Stock Option (Right to Buy) | 9.3k | $23.99 | $223.2k | | 02/21/2020 |
| 02/21/2020 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Grant | Common Stock | 5.2k | $23.99 | $125k | | 02/21/2020 |
| 06/20/2019 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Exercise | Director Stock Option (Right to Buy) | 10k | $9.13 | $91.3k | | 06/20/2019 |
| 04/25/2019 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Exercise | Director Stock Option (Right to Buy) | 10k | $9.13 | $91.3k | | 04/25/2019 |
| 02/22/2019 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Grant | Director Stock Option (Right to Buy) | 12.4k | $36.75 | $456.7k | | 02/22/2019 |
| 02/22/2019 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Grant | Director Stock Option (Right to Buy) | 12.4k | $36.75 | $456.7k | | 02/22/2019 |
| 08/20/2018 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Exercise | Director Stock Option (Right to Buy) | 8.7k | $7.90 | $68.9k | | 08/20/2018 |
| 08/20/2018 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Exercise | Director Stock Option (Right to Buy) | 7.5k | $9.24 | $68.9k | | 08/20/2018 |
| 03/22/2018 | ARADIGM CORP | ARDM | Grant | Stock Option (Right to Buy) | 276k | $1.31 | $361.6k | | 03/22/2018 |
| 02/23/2018 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Grant | Director Stock Option (Right to Buy) | 8.6k | $39.40 | $339.4k | | 02/23/2018 |
| 06/13/2017 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Grant | Director Stock Option (Right to Buy) | 6k | $38.60 | $233k | | 06/13/2017 |
| 06/01/2017 | ARADIGM CORP | ARDM | Grant | Stock Option (Right to Buy) | 110.5k | $1.39 | $153.6k | | 06/01/2017 |
| 02/24/2017 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Grant | Director Stock Option (Right to Buy) | 7.9k | $25.30 | $200k | | 02/24/2017 |
| 03/01/2016 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Grant | Director Stock Option (Right to Buy) | 15k | $12.98 | $194.7k | | 03/01/2016 |
| 03/03/2015 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Grant | Director Stock Option (Right to Buy) | 20k | $9.13 | $182.6k | | 03/03/2015 |
| 12/16/2014 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Exercise | Director Stock Option (Right to Buy) | 2.2k | $4.24 | $9.3k | | 12/16/2014 |
| 01/21/2014 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Grant | Director Stock Option (Right to Buy) | 7.5k | $9.24 | $68.9k | | 12/12/2013 |
| 12/12/2013 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Exercise | Director Stock Option (Right to Buy) | 2.2k | $4.24 | $9.3k | | 12/12/2013 |
| 03/21/2013 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Purchase | Common Stock | 3k | $5.50 | $16.5k | | 03/21/2013 |
| 12/14/2012 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Exercise | Stock Option (right to buy) | 2.2k | $4.24 | $9.3k | | 12/14/2012 |