| In millions, except per share items | Dec-31-16 | Dec-31-15 | Dec-31-14 | Dec-31-13 | Dec-31-12 | Dec-31-11 | Dec-31-10 | Dec-31-09 |
| | 10-K | 10-K | 10-K | 10-K | 10-K | 10-K | 10-K | 10-K |
| Revenues: |
| Net product sales | 22.0 | | | | | | | |
| Royalties | 5.9 | 10.6 | 1.3 | | | | | |
| Other | 5.8 | 13.9 | 54.2 | | | | | |
| Total revenues [+] | 33.7 | 24.5 | 55.5 | 3.4 | 3.4 | 4.4 | 1.2 | 0.1 |
| Licensing | | | | | | 1.0 | 0.1 | 0.1 |
| Royalties | 5.9 | 10.6 | 1.3 | | | 12.8 | | |
| Products | 22.0 | | | | | | | |
| Revenue growth [+] | 37.8% | -55.9% | 1519.6% | 0.0% | -22.1% | 257.4% | 1298.9% | 0.0% |
| Royalties | -44.0% | 720.0% | | | | | | |
| Cost of goods sold | 8.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| Gross profit | 25.7 | 24.5 | 55.5 | 3.4 | 3.4 | 4.4 | 1.2 | 0.1 |
| Gross margin | 76.3% | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% |
| Selling, general and administrative [+] | 118.6 | 43.8 | 28.6 | 23.9 | 20.0 | 19.5 | 24.5 | 18.2 |
| General and administrative | | | | 23.9 | 20.0 | 19.5 | 24.5 | 18.2 |
| Research and development | 38.0 | 40.8 | 57.4 | 56.7 | 73.7 | 12.8 | 28.1 | 47.4 |
| Other operating expenses | -76.9 | | | | | | | |
| EBITDA [+] | -50.2 | -59.8 | -30.4 | -77.1 | -89.9 | -27.4 | -50.9 | -65.1 |
| EBITDA growth | -16.0% | 96.9% | -60.6% | -14.3% | 227.7% | -46.1% | -21.7% | -31.1% |
| EBITDA margin | -149.0% | -244.6% | -54.7% | -2249.2% | -2623.3% | -623.8% | -4136.6% | -73922.7% |
| Depreciation | 0.4 | 0.2 | 0.1 | 0.1 | 0.3 | 0.4 | 0.5 | 0.5 |
| EBITA | -50.7 | -60.1 | -30.5 | -77.2 | -90.2 | -27.9 | -51.4 | -65.5 |
| EBITA margin | -150.3% | -245.5% | -55.0% | -2252.0% | -2632.4% | -633.8% | -4175.1% | -74465.9% |
| Amortization of intangibles | 3.3 | | | | | | | |
| EBIT [+] | -54.0 | -60.1 | -30.5 | -77.2 | -90.2 | -27.9 | -51.4 | -65.5 |
| EBIT growth | -10.1% | 96.7% | -60.5% | -14.5% | 223.6% | -45.7% | -21.6% | -30.9% |
| EBIT margin | -160.1% | -245.5% | -55.0% | -2252.0% | -2632.4% | -633.8% | -4175.1% | -74465.9% |
| Non-recurring items [+] | 3.0 | | | | | | | |
| Loss on contingent liability | 3.0 | | | | | | | |
| Interest expense, net [+] | 7.2 | 7.2 | 7.0 | 0.5 | -0.1 | 0.2 | 0.5 | 1.0 |
| Interest expense | 7.9 | 7.4 | 7.1 | 0.5 | 0.0 | 0.2 | 0.6 | 1.4 |
| Interest income | 0.6 | 0.2 | 0.1 | 0.1 | 0.1 | 0.0 | 0.1 | 0.3 |
| Other income (expense), net [+] | 39.8 | 0.0 | | | | | | |
| Gain (loss) on debt retirement | 18.3 | | | | | | | |
| Gain (loss) on foreign currency transactions | -3.9 | 0.0 | | | | | | |
| Change in fair value of warrants | 25.4 | | | | | | | |
| Change in value of contingent liability | 3.0 | | | | | | | |
| Other | 32.6 | -7.3 | -7.0 | -0.5 | 0.1 | -0.2 | -0.5 | -1.0 |
| Pre-tax income | -24.4 | -67.3 | -37.5 | -77.7 | -90.1 | -28.1 | -51.9 | -66.6 |
| Income taxes | 0.1 | 1.4 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| Tax rate | | | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% |
| Net income | -24.5 | -68.7 | -37.5 | -77.7 | -90.1 | -28.1 | -51.9 | -66.6 |
| Net margin | -72.8% | -280.8% | -67.6% | -2265.8% | -2628.2% | -637.8% | -4217.3% | -75638.6% |
| |
| Basic EPS [+] | ($1.68) | ($5.24) | ($3.17) | ($0.80) | ($1.27) | ($0.58) | ($1.10) | ($1.67) |
| Growth | -67.9% | 65.1% | 294.3% | -36.8% | 119.1% | -47.0% | -34.3% | -39.6% |
| Diluted EPS [+] | ($1.68) | ($5.24) | ($3.17) | ($0.80) | ($1.27) | ($0.58) | ($1.10) | ($1.67) |
| Growth | -67.9% | 65.1% | 294.3% | -36.8% | 119.1% | -47.0% | -34.3% | -39.6% |
| |
| Shares outstanding (basic) [+] | 14.6 | 13.1 | 11.8 | 96.5 | 70.7 | 48.3 | 47.4 | 39.9 |
| Growth | 11.2% | 10.9% | -87.7% | 36.4% | 46.5% | 1.9% | 18.7% | 18.2% |
| Shares outstanding (diluted) [+] | 14.6 | 13.1 | 11.8 | 96.5 | 70.7 | 48.3 | 47.4 | 39.9 |
| Growth | 11.2% | 10.9% | -87.7% | 36.4% | 46.5% | 1.9% | 18.7% | 18.2% |
| |
| EBIT is a non-GAAP figure that excludes all non-recurring expenses: restructuring costs, asset impairments, IPR&D writeoffs, and other unusual charges. |