| In millions, except per share items | Dec-31-22 | Dec-31-21 | Dec-31-20 | Dec-31-19 | Dec-31-18 | Dec-31-17 | Dec-31-16 | Dec-31-15 |
| | 10-K | 10-K | 10-K | 10-K | 10-K | 10-K | 10-K | 10-K |
| Revenues [+] | 39.0 | 11.0 | 6.9 | 6.0 | 5.9 | 10.7 | 1.5 | 23.3 |
| Licensing | | | | | | | 1.3 | 11.6 |
| Contracts | | | | | | | 0.2 | 11.7 |
| Revenue growth | 255.1% | 58.9% | 15.0% | 1.1% | -44.4% | 617.6% | -93.6% | 55.7% |
| Cost of goods sold | 0.0 | 0.0 | 0.0 | -150.1 | 0.0 | 0.0 | 0.0 | 0.0 |
| Gross profit | 39.0 | 11.0 | 6.9 | 156.1 | 5.9 | 10.7 | 1.5 | 23.3 |
| Gross margin | 100.0% | 100.0% | 100.0% | 2596.8% | 100.0% | 100.0% | 100.0% | 100.0% |
| Selling, general and administrative [+] | 17.8 | 17.1 | 14.8 | 17.7 | 16.0 | 16.1 | 39.4 | 26.4 |
| General and administrative | 17.8 | 17.1 | 14.8 | 17.7 | 16.0 | 16.1 | 39.4 | 26.4 |
| Research and development | 84.4 | 65.5 | 49.3 | 57.6 | 57.9 | 62.7 | 61.3 | 51.5 |
| Equity in earnings | | | -2.5 | -22.5 | | | | |
| Other operating expenses | 2.2 | 1.9 | 0.5 | 150.1 | | 2.0 | 1.1 | 0.6 |
| EBITDA [+] | -64.0 | -71.8 | -58.3 | -91.8 | -68.0 | -68.1 | -99.2 | -54.7 |
| EBITDA growth | -10.8% | 23.1% | -36.5% | 35.1% | -0.2% | -31.3% | 81.5% | 68.5% |
| EBITDA margin | -164.1% | -653.2% | -843.3% | -1527.8% | -1143.7% | -636.5% | -6653.3% | -234.9% |
| Depreciation and amortization | 1.4 | 1.8 | 2.0 | 2.0 | 2.2 | 2.0 | 1.1 | 0.6 |
| EBIT [+] | -65.5 | -73.5 | -60.3 | -93.9 | -70.2 | -70.1 | -100.3 | -55.3 |
| EBIT growth | -11.0% | 22.0% | -35.8% | 33.8% | 0.1% | -30.1% | 81.5% | 67.6% |
| EBIT margin | -167.8% | -669.1% | -872.0% | -1561.6% | -1180.4% | -655.4% | -6726.5% | -237.4% |
| Non-recurring items [+] | | | 0.1 | 72.6 | 19.6 | 40.8 | 391.3 | 48.7 |
| Asset impairment | | | | 66.3 | 14.8 | 40.8 | 391.3 | 39.0 |
| Legal settlement | | | | 6.3 | | | | |
| Loss on contingent liability | | | | -0.2 | | | | |
| Interest income, net [+] | 0.5 | -2.7 | -3.3 | 0.0 | 2.8 | 1.3 | 1.4 | 0.7 |
| Interest expense | 1.7 | 2.9 | 4.0 | 2.1 | 0.2 | 0.3 | | |
| Interest income | 2.2 | 0.1 | 0.7 | 2.1 | 3.0 | 1.5 | 1.4 | 0.7 |
| Other income (expense), net [+] | 4.4 | 0.0 | -0.1 | 0.0 | 25.6 | 0.9 | 1.1 | 24.3 |
| Gain (loss) on foreign currency transactions | 0.0 | 0.0 | -0.1 | 0.0 | -1.0 | 2.3 | 1.1 | 21.8 |
| Change in value of contingent liability | 2.2 | 1.9 | 0.5 | | | | | |
| Pre-tax income | -60.6 | -76.2 | -63.7 | -166.4 | -61.3 | -108.7 | -489.2 | -78.9 |
| Income taxes | 4.4 | 0.0 | 0.0 | -12.7 | -4.3 | -24.3 | -105.0 | -16.2 |
| Tax rate | | 0.0% | 0.0% | 7.6% | 7.0% | 22.4% | 21.5% | 20.5% |
| Net income | -69.5 | -88.4 | -75.9 | -164.9 | -67.2 | -85.3 | -384.2 | -62.7 |
| Net margin | -178.0% | -804.4% | -1097.3% | -2742.8% | -1129.5% | -797.4% | -25765.5% | -269.5% |
| |
| Basic EPS [+] | ($0.46) | ($0.83) | ($1.00) | ($2.89) | ($1.21) | ($1.56) | ($7.24) | ($1.38) |
| Growth | -44.7% | -16.8% | -65.4% | 137.8% | -22.1% | -78.5% | 424.7% | -23.3% |
| Diluted EPS [+] | ($0.46) | ($0.83) | ($1.00) | ($2.89) | ($1.21) | ($1.56) | ($7.24) | ($1.38) |
| Growth | -44.7% | -16.8% | -65.4% | 137.8% | -22.1% | -78.5% | 424.7% | -23.3% |
| |
| Shares outstanding (basic) [+] | 150.9 | 106.2 | 75.8 | 57.1 | 55.3 | 54.7 | 53.1 | 45.5 |
| Growth | 42.1% | 40.1% | 32.8% | 3.2% | 1.1% | 3.1% | 16.7% | 110.4% |
| Shares outstanding (diluted) [+] | 150.9 | 106.2 | 75.8 | 57.1 | 55.3 | 54.7 | 53.1 | 45.5 |
| Growth | 42.1% | 40.1% | 32.8% | 3.2% | 1.1% | 3.1% | 16.7% | 110.4% |
| |
| EBIT is a non-GAAP figure that excludes all non-recurring expenses: restructuring costs, asset impairments, IPR&D writeoffs, and other unusual charges. |