| In millions, except per share items | Dec-31-21 | Dec-31-20 | Dec-31-19 | Dec-31-18 | Dec-31-17 | Dec-31-16 | Dec-31-15 |
| | 10-K | 10-K | 10-K | 10-K | 10-K | 10-K | 10-K |
| Revenues: |
| Product sales | | | | | | | 27.9 |
| Other | | | | | | | 5.7 |
| Total revenues [+] | 12.3 | 4.3 | 0.0 | 23.1 | 14.7 | 10.0 | 33.6 |
| Royalties | 35.0 | | | | | | |
| Products | | | | | | 9.8 | 27.9 |
| Revenue growth | 185.3% | | -100.0% | 57.4% | 46.8% | -70.3% | |
| Cost of goods sold | 0.0 | 0.0 | 0.0 | 11.2 | 5.0 | 12.5 | 16.9 |
| Gross profit | 12.3 | 4.3 | 0.0 | 11.9 | 9.6 | -2.5 | 16.7 |
| Gross margin | 100.0% | 100.0% | | 51.4% | 65.8% | -24.9% | 49.6% |
| Selling, general and administrative [+] | 14.7 | 14.0 | 16.2 | 28.1 | 34.6 | 36.2 | 43.0 |
| General and administrative | 14.7 | 14.0 | 16.2 | | | | |
| Research and development | 19.0 | 17.9 | 24.8 | 35.4 | 29.0 | 29.1 | 34.7 |
| EBITDA [+] | -20.3 | -26.1 | -38.7 | -49.3 | -50.8 | -64.4 | -58.2 |
| EBITDA growth | -22.4% | -32.6% | -21.4% | -3.0% | -21.1% | 10.7% | |
| EBITDA margin | -164.8% | -605.4% | | -213.6% | -346.7% | -644.9% | -173.2% |
| Depreciation | 1.1 | 1.4 | 2.2 | 2.4 | 2.3 | 2.6 | -0.5 |
| EBITA | -21.4 | -27.5 | -41.0 | -51.7 | -53.1 | -67.0 | -57.7 |
| EBITA margin | -174.1% | -638.1% | | -224.0% | -362.6% | -670.6% | -171.7% |
| Amortization of intangibles | | | | | 0.8 | 0.8 | 3.4 |
| EBIT [+] | -21.4 | -27.5 | -41.0 | -51.7 | -53.9 | -67.8 | -61.1 |
| EBIT growth | -22.2% | -32.9% | -20.7% | -4.2% | -20.4% | 10.9% | |
| EBIT margin | -174.1% | -638.1% | | -224.0% | -368.1% | -678.6% | -181.8% |
| Non-recurring items [+] | | | | | | 71.0 | |
| Asset impairment | | | | | | 71.0 | |
| Other income (expense), net [+] | -8.0 | -3.4 | -2.1 | -2.0 | -1.9 | -0.8 | -0.2 |
| Gain (loss) on debt retirement | | -2.1 | | | | | |
| Other | -8.0 | -1.3 | | -2.0 | -1.9 | -0.8 | -0.2 |
| Pre-tax income | -29.4 | -30.9 | -43.1 | -53.7 | -55.9 | -139.6 | -61.3 |
| Income taxes | -1.0 | -13.2 | -2.6 | 0.0 | -23.3 | -19.7 | -2.0 |
| Tax rate | 3.2% | 42.6% | 6.1% | 0.0% | 41.7% | 14.1% | 3.3% |
| Earnings from continuing ops | -30.4 | -44.1 | -45.7 | -53.7 | -72.2 | -127.4 | -59.3 |
| Earnings from discontinued ops | 1.0 | 13.2 | 2.6 | | 39.6 | 7.5 | |
| Net income | -29.4 | -30.9 | -43.1 | -53.7 | -32.6 | -119.9 | -59.3 |
| Net margin | -239.2% | -717.6% | | -232.8% | -222.3% | -1200.7% | -176.5% |
| |
| Basic EPS [+] | ($6.48) | ($13.00) | ($15.66) | ($2.39) | ($3.38) | ($6.29) | ($2.93) |
| Growth | -50.2% | -17.0% | 556.3% | -29.4% | -46.3% | 114.6% | |
| Diluted EPS [+] | ($6.48) | ($13.00) | ($15.66) | ($2.39) | ($3.38) | ($6.29) | ($2.93) |
| Growth | -50.2% | -17.0% | 556.3% | -29.4% | -46.3% | 114.6% | |
| |
| Shares outstanding (basic) [+] | 4.7 | 3.4 | 2.9 | 22.5 | 21.3 | 20.2 | 20.2 |
| Growth | 38.3% | 16.2% | -87.0% | 5.5% | 5.4% | 0.0% | |
| Shares outstanding (diluted) [+] | 4.7 | 3.4 | 2.9 | 22.5 | 21.3 | 20.2 | 20.2 |
| Growth | 38.3% | 16.2% | -87.0% | 5.5% | 5.4% | 0.0% | |
| |
| EBIT is a non-GAAP figure that excludes all non-recurring expenses: restructuring costs, asset impairments, IPR&D writeoffs, and other unusual charges. |