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| In millions, except per share items | Dec-31-15 | Dec-31-14 | Dec-31-13 | Dec-31-12 | Dec-31-11 | Dec-31-10 | Dec-31-09 | Dec-31-08 |
| | 10-K | 10-K | 10-K | 10-K | 10-K | 10-K | 10-K | 10-K |
| Revenues: |
| Product sales | 2.4 | 2.6 | 0.9 | | | | | |
| Other | 2.7 | 3.0 | 47.0 | | | | | |
| Total revenues [+] | 5.0 | 5.6 | 47.8 | 4.1 | 5.7 | 42.9 | 9.5 | 0.5 |
| Royalties | | | | | | | | 61.6 |
| Products | 2.4 | 2.6 | 0.9 | | | | | |
| Net interest income | | | | | | -1.6 | -0.5 | |
| Revenue growth [+] | -9.6% | -88.4% | 1075.4% | -28.1% | -86.8% | 350.7% | 1857.6% | -98.9% |
| Product sales | -8.2% | 193.4% | | | | | | |
| Cost of goods sold | 21.1 | 15.9 | 11.2 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| Gross profit | -16.1 | -10.4 | 36.6 | 4.1 | 5.7 | 42.9 | 9.5 | 0.5 |
| Gross margin | -320.4% | -186.4% | 76.6% | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% |
| Selling, general and administrative [+] | 12.2 | 13.3 | 15.8 | 11.1 | 11.8 | 14.0 | 15.4 | 17.6 |
| General and administrative | 12.2 | 13.3 | 15.8 | 11.1 | 11.8 | 14.0 | 15.4 | 17.6 |
| Research and development | 11.7 | 13.7 | 19.1 | 21.8 | 28.3 | 33.5 | 39.8 | |
| Other operating expenses | 27.1 | 8.1 | | | | | | 61.6 |
| EBITDA [+] | -64.2 | -42.2 | 5.1 | -24.5 | -29.9 | -0.1 | -40.8 | -73.4 |
| EBITDA growth | 52.0% | -928.8% | -120.8% | -18.0% | 31411.6% | -99.8% | -44.4% | 29.9% |
| EBITDA margin | -1276.5% | -759.1% | 10.6% | -602.9% | -528.9% | -0.2% | -429.1% | -15108.2% |
| Depreciation and amortization | 3.0 | 3.4 | 3.3 | 4.3 | 4.4 | 4.6 | 4.9 | 5.3 |
| EBIT [+] | -67.2 | -45.6 | 1.8 | -28.9 | -34.4 | -4.7 | -45.7 | -78.7 |
| EBIT growth | 47.3% | -2676.6% | -106.1% | -16.0% | 638.8% | -89.8% | -42.0% | 30.0% |
| EBIT margin | -1336.2% | -820.1% | 3.7% | -709.4% | -607.2% | -10.8% | -480.0% | -16197.5% |
| Non-recurring items | -27.1 | -8.1 | | | | | 2.0 | |
| Interest expense | 8.4 | 7.4 | 1.5 | 1.4 | 2.2 | | | 0.9 |
| Interest expense | 8.4 | 7.4 | 1.5 | 1.4 | 2.2 | 1.6 | | 0.9 |
| Other income (expense), net [+] | 27.2 | 8.2 | -39.9 | 2.3 | -4.0 | 4.8 | -8.4 | 2.6 |
| Change in value of contingent liability | 27.1 | 8.1 | -39.9 | 1.9 | -4.0 | | | |
| Pre-tax income | -21.3 | -36.7 | -39.6 | -28.0 | -40.5 | -1.5 | -56.1 | -77.0 |
| Income taxes | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 47.6 | 0.0 |
| Tax rate | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | | 0.0% |
| Minority interest | | | | | | | 14.0 | |
| Net income | -21.3 | -36.7 | -39.6 | -28.0 | -40.5 | -1.5 | -70.1 | -77.0 |
| Net margin | -424.0% | -660.5% | -82.8% | -687.4% | -716.1% | -3.5% | -736.3% | -15852.1% |
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| Basic EPS [+] | ($1.08) | ($2.07) | ($2.38) | ($2.24) | ($5.97) | ($0.27) | ($2.68) | |
| Growth | -47.9% | -13.1% | 5.9% | -62.4% | 2134.7% | -90.0% | | |
| Diluted EPS [+] | ($1.08) | ($2.07) | ($2.38) | ($2.24) | ($5.97) | ($0.27) | ($2.68) | |
| Growth | -47.9% | -13.1% | 5.9% | -62.4% | 2134.7% | -90.0% | | |
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| Shares outstanding (basic) [+] | 19.8 | 17.8 | 16.7 | 12.5 | 6.8 | 5.5 | 26.1 | |
| Growth | 11.4% | 6.7% | 33.7% | 83.8% | 22.5% | -78.8% | | |
| Shares outstanding (diluted) [+] | 19.8 | 17.8 | 16.7 | 12.5 | 6.8 | 5.5 | 26.1 | |
| Growth | 11.4% | 6.7% | 33.7% | 83.8% | 22.5% | -78.8% | | |
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| EBIT is a non-GAAP figure that excludes all non-recurring expenses: restructuring costs, asset impairments, IPR&D writeoffs, and other unusual charges. |
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