| In millions, except per share items | Dec-31-22 | Dec-31-21 | Dec-31-20 | Dec-31-19 | Dec-31-18 | Dec-31-17 | Dec-31-16 | Dec-31-15 |
| | 10-K | 10-K | 10-K | 10-K | 10-K | 10-K | 10-K | 10-K |
| Revenues: |
| Non-US | 213.3 | 210.1 | 180.8 | 129.8 | 84.0 | | | |
| UNITED STATES | 115.9 | 95.4 | 80.0 | 52.5 | 7.2 | | | |
| Total revenues [+] | 329.2 | 305.5 | 260.9 | 182.2 | 91.2 | 36.9 | 5.0 | 0.0 |
| Products | 329.2 | 305.5 | 260.9 | 182.2 | 91.2 | | | |
| Revenue growth [+] | 7.8% | 17.1% | 43.2% | 99.7% | 147.1% | 644.9% | | -100.0% |
| Non-US | 1.5% | 16.2% | 39.4% | 54.4% | | | | |
| UNITED STATES | 21.6% | 19.2% | 52.5% | 626.5% | | | | |
| Cost of goods sold | 38.6 | 34.5 | 31.0 | 22.0 | 14.4 | 6.2 | 0.8 | 0.0 |
| Gross profit | 290.6 | 271.0 | 229.8 | 160.3 | 76.8 | 30.7 | 4.1 | 0.0 |
| Gross margin | 88.3% | 88.7% | 88.1% | 87.9% | 84.2% | 83.1% | 83.2% | |
| Selling, general and administrative | 213.0 | 192.7 | 156.4 | 169.9 | 127.2 | 88.7 | 71.2 | 47.3 |
| Research and development | 276.7 | 272.0 | 308.4 | 286.4 | 270.9 | 149.3 | 104.8 | 76.9 |
| EBITDA [+] | -199.1 | -193.7 | -235.0 | -296.0 | -321.3 | -207.3 | -171.8 | -124.2 |
| EBITDA growth | 2.8% | -17.6% | -20.6% | -7.9% | 55.0% | 20.6% | 38.3% | 85.1% |
| EBITDA margin | -60.5% | -63.4% | -90.1% | -162.4% | -352.1% | -561.3% | -3465.5% | |
| Depreciation and amortization | 5.3 | 6.2 | 8.8 | 4.8 | 4.2 | 3.6 | 3.2 | 1.8 |
| EBIT [+] | -204.4 | -199.9 | -243.9 | -300.7 | -325.5 | -210.9 | -175.1 | -126.0 |
| EBIT growth | 2.3% | -18.0% | -18.9% | -7.6% | 54.3% | 20.5% | 38.9% | 83.6% |
| EBIT margin | -62.1% | -65.4% | -93.5% | -165.0% | -356.7% | -571.0% | -3530.9% | |
| Non-recurring items [+] | 7.7 | 6.5 | 3.1 | 3.3 | 3.3 | 231.1 | 6.8 | 4.4 |
| Asset impairment | 6.6 | | | | | 465.4 | | |
| Unusual expense | 1.1 | 6.5 | 3.1 | 3.3 | 3.3 | -234.3 | 6.8 | 4.4 |
| Interest expense, net [+] | 34.1 | 32.0 | 19.2 | 8.6 | 11.9 | 13.1 | 3.8 | 0.6 |
| Interest expense | 37.1 | 32.5 | 22.4 | 18.9 | 22.4 | 17.2 | 5.4 | 1.6 |
| Interest income | 3.0 | 0.5 | 3.2 | 10.2 | 10.5 | 4.1 | 1.6 | 0.9 |
| Other income (expense), net [+] | 4.2 | -3.2 | -8.1 | -43.3 | -8.4 | 6.0 | -18.1 | -1.0 |
| Gain (loss) on debt retirement | | -0.3 | -7.3 | | | | | |
| Unrealized gain/loss on derivatives | | | | | -2.7 | | | |
| Change in fair value of warrants | | | | | -2.7 | | | |
| Other | 4.2 | -2.9 | -0.8 | -2.6 | -5.6 | 6.0 | -4.8 | -0.1 |
| Pre-tax income | -242.0 | -241.6 | -274.3 | -355.9 | -349.1 | -449.1 | -203.8 | -132.1 |
| Income taxes | -5.5 | 8.9 | 2.6 | 0.5 | -0.1 | -165.1 | -3.7 | 0.0 |
| Tax rate | 2.3% | | | | 0.0% | 36.8% | 1.8% | 0.0% |
| Net income | -236.6 | -250.5 | -276.9 | -356.4 | -349.0 | -284.0 | -200.0 | -132.1 |
| Net margin | -71.9% | -82.0% | -106.1% | -195.6% | -382.5% | -769.0% | -4034.7% | |
| |
| Basic EPS [+] | ($0.82) | ($0.92) | ($1.07) | ($1.48) | ($1.88) | ($1.85) | ($1.49) | ($1.20) |
| Growth | -11.3% | -13.7% | -27.9% | -21.1% | 1.4% | 24.4% | 23.8% | 29.8% |
| Diluted EPS [+] | ($0.82) | ($0.92) | ($1.07) | ($1.48) | ($1.88) | ($1.85) | ($1.49) | ($1.20) |
| Growth | -11.3% | -13.7% | -27.9% | -21.1% | 1.4% | 24.4% | 23.8% | 29.8% |
| |
| Shares outstanding (basic) [+] | 289.1 | 271.4 | 258.9 | 240.4 | 185.8 | 153.4 | 134.4 | 109.9 |
| Growth | 6.5% | 4.8% | 7.7% | 29.4% | 21.2% | 14.1% | 22.3% | 47.7% |
| Shares outstanding (diluted) [+] | 289.1 | 271.4 | 258.9 | 240.4 | 185.8 | 153.4 | 134.4 | 109.9 |
| Growth | 6.5% | 4.8% | 7.7% | 29.4% | 21.2% | 14.1% | 22.3% | 47.7% |
| |
| EBIT is a non-GAAP figure that excludes all non-recurring expenses: restructuring costs, asset impairments, IPR&D writeoffs, and other unusual charges. |