| In millions, except per share items | Dec-31-11 | Dec-31-10 | Dec-31-09 | Dec-31-08 | Dec-31-07 | Dec-31-06 | Dec-31-05 | Dec-31-04 |
| | 10-K | 10-K | 10-K | 10-K | 10-K | 10-K | 10-K | 10-K |
| Revenues: |
| Product sales | 562.6 | 522.7 | 483.8 | 429.2 | | | | |
| Collaborative research revenue | 7.7 | 14.5 | 7.9 | 20.6 | 16.6 | 15.9 | 25.8 | 27.1 |
| Royalty and license revenue | 6.0 | 6.1 | 6.6 | 22.9 | 15.5 | 13.5 | 8.5 | 20.0 |
| Other | | | | | 370.9 | 325.3 | 271.7 | 222.6 |
| Total revenues [+] | 576.2 | 543.3 | 498.3 | 472.7 | 403.0 | 354.8 | 306.0 | 269.7 |
| Licensing | 6.0 | 6.1 | 6.6 | 22.9 | | | | |
| Products | 562.6 | 522.7 | 483.8 | 429.2 | | | | |
| Revenue growth [+] | 6.1% | 9.0% | 5.4% | 17.3% | 13.6% | 15.9% | 13.4% | 30.2% |
| Product sales | 7.6% | 8.1% | 12.7% | | | | | |
| Collaborative research revenue | -47.1% | 83.5% | -61.6% | 23.8% | 4.3% | -38.3% | -4.7% | 76.1% |
| Royalty and license revenue | -2.2% | -8.0% | -71.0% | 47.5% | 14.8% | 59.6% | -57.7% | 536.9% |
| Cost of goods sold | 173.6 | 169.2 | 152.4 | 128.0 | 119.6 | 103.9 | 83.9 | 59.9 |
| Gross profit | 402.6 | 374.1 | 345.9 | 344.7 | 283.4 | 250.9 | 222.1 | 209.8 |
| Gross margin | 69.9% | 68.9% | 69.4% | 72.9% | 70.3% | 70.7% | 72.6% | 77.8% |
| Selling, general and administrative [+] | 139.8 | 116.3 | 115.7 | 98.2 | 86.9 | 82.0 | 63.3 | 58.8 |
| Sales and marketing | 68.4 | 59.5 | 53.9 | 45.9 | 39.9 | 37.1 | 31.1 | 27.2 |
| General and administrative | 71.4 | 56.8 | 61.8 | 52.3 | 47.0 | 44.9 | 32.1 | 31.6 |
| Research and development | 112.7 | 111.1 | 106.0 | 101.1 | | | | |
| Other operating expenses | 8.4 | 7.7 | 4.1 | | 97.1 | 84.5 | 71.8 | 68.5 |
| EBITDA [+] | 188.3 | 183.5 | 160.5 | 180.1 | 133.5 | 111.8 | 109.6 | 100.7 |
| EBITDA growth | 2.6% | 14.3% | -10.9% | 35.0% | 19.4% | 2.0% | 8.8% | 47.8% |
| EBITDA margin | 32.7% | 33.8% | 32.2% | 38.1% | 33.1% | 31.5% | 35.8% | 37.4% |
| Depreciation | 25.6 | 26.8 | 27.6 | 34.7 | 34.2 | 27.5 | 22.6 | 18.2 |
| EBITA | 162.7 | 156.6 | 132.9 | 145.4 | 99.3 | 84.3 | 87.0 | 82.5 |
| EBITA margin | 28.2% | 28.8% | 26.7% | 30.8% | 24.6% | 23.8% | 28.4% | 30.6% |
| Amortization of intangibles | 21.0 | 17.7 | 12.8 | | | | | |
| EBIT [+] | 141.7 | 138.9 | 120.1 | 145.4 | 99.3 | 84.3 | 87.0 | 82.5 |
| EBIT growth | 2.0% | 15.7% | -17.4% | 46.4% | 17.8% | -3.1% | 5.4% | 57.6% |
| EBIT margin | 24.6% | 25.6% | 24.1% | 30.8% | 24.6% | 23.8% | 28.4% | 30.6% |
| Non-recurring items [+] | 15.4 | 1.1 | | | | | | |
| Asset impairment | 12.7 | | | | | | | |
| Interest income, net [+] | 6.6 | 9.5 | 19.7 | 16.8 | 12.8 | 8.3 | 4.7 | |
| Interest expense | 2.1 | 2.2 | 1.9 | | | | 0.2 | |
| Interest income | 8.7 | 11.8 | 21.6 | 16.8 | 12.8 | 8.3 | 4.9 | |
| Other income (expense), net | -39.7 | 7.8 | -0.1 | -1.3 | -0.5 | 0.4 | 0.0 | 2.1 |
| Pre-tax income | 93.2 | 155.2 | 139.8 | 160.9 | 111.6 | 93.0 | 91.7 | 84.6 |
| Income taxes | 43.0 | 48.3 | 48.0 | 53.9 | 25.5 | 33.5 | 31.6 | 30.0 |
| Tax rate | 46.2% | 31.1% | 34.3% | 33.5% | 22.8% | 36.0% | 34.5% | 35.5% |
| Minority interest | | | | | | | 0.1 | |
| Net income | 50.1 | 106.7 | 91.4 | 107.0 | 86.1 | 59.5 | 60.1 | 54.6 |
| Net margin | 8.7% | 19.6% | 18.4% | 22.6% | 21.4% | 16.8% | 19.6% | 20.2% |
| |
| Basic EPS [+] | $1.06 | $2.20 | $1.82 | $1.99 | $1.63 | $1.15 | $1.19 | $1.10 |
| Growth | -51.8% | 21.0% | -8.8% | 22.1% | 41.2% | -2.8% | 7.5% | 49.9% |
| Diluted EPS [+] | $1.03 | $2.18 | $1.79 | $1.95 | $1.58 | $1.12 | $1.15 | $1.06 |
| Growth | -52.4% | 21.2% | -8.1% | 23.2% | 41.4% | -2.2% | 7.9% | 47.7% |
| |
| Shares outstanding (basic) [+] | 47.3 | 48.6 | 50.4 | 53.7 | 52.9 | 51.5 | 50.6 | 49.4 |
| Growth | -2.7% | -3.6% | -6.3% | 1.7% | 2.6% | 1.8% | 2.4% | 3.0% |
| Shares outstanding (diluted) [+] | 48.4 | 49.0 | 51.0 | 54.8 | 54.4 | 53.1 | 52.4 | 51.4 |
| Growth | -1.3% | -3.8% | -7.0% | 0.8% | 2.4% | 1.3% | 2.0% | 4.6% |
| |
| EBIT is a non-GAAP figure that excludes all non-recurring expenses: restructuring costs, asset impairments, IPR&D writeoffs, and other unusual charges. |