| In millions, except per share items | Dec-31-13 | Dec-31-12 | Dec-31-11 | Dec-31-10 | Dec-31-09 | Dec-31-08 |
| | 10-K | 10-K | 10-K | 10-K | 10-K | 10-K |
| Revenue: | | | | | | |
| Milestones | 45.0 | 20.0 | | 7.5 | | |
| Royalties | 26.0 | 20.5 | 4.5 | 1.3 | 0.9 | |
| Total revenue | 71.0 | 40.5 | 4.5 | 9.0 | 6.3 | 18.4 |
| Total revenue growth | 75.3% | 802.2% | -50.0% | 42.3% | -65.7% | |
| Research and development expenses | 82.7 | 69.5 | 44.2 | 50.1 | 11.8 | |
| Selling, general and administrative expenses | 12.7 | 11.3 | 8.8 | 8.3 | 2.6 | |
| Depreciation and amortization | 0.1 | 0.1 | 0.1 | 0.1 | 0.0 | |
| Total operating expenses | 95.4 | 80.9 | 53.0 | 141.5 | 14.6 | |
| Operating income (loss) | -24.4 | -40.3 | -48.6 | -49.5 | -8.3 | |
| Operating margin | -34.4% | -99.6% | -1081.4% | -551.3% | -131.6% | |
| Interest expense | 5.0 | 2.5 | 0.4 | | | |
| Other income, net | 0.1 | 0.0 | 0.0 | 0.0 | 0.0 | |
| Income (loss) before provision for income taxes | -29.3 | -42.9 | -49.0 | -49.5 | -8.3 | 6.8 |
| Less provision for income taxes | 0.3 | 0.0 | 0.0 | 0.0 | 0.6 | |
| Tax rate | | | | | | 0.0% |
| Net income (loss) | -29.7 | -42.9 | -49.0 | -54.7 | -8.9 | |
| |
| Net income (loss) per basic share (in Dollars per share) | ($2.92) | ($4.29) | ($4.96) | ($5.53) | ($0.90) | |
| Net income (loss) per diluted share (in Dollars per share) | ($2.92) | ($4.29) | ($4.96) | ($5.53) | ($0.90) | |
| |
| Weighted-average shares used to compute net income | 10.1 | 10.0 | 9.9 | 9.9 | | |
| Weighted-average shares used to compute net income | 10.1 | 10.0 | 9.9 | | | |