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In millions, except per share items | Dec-31-22 | Dec-31-21 | Dec-31-20 | Dec-31-19 | Dec-31-18 | Dec-31-17 | Dec-31-16 | Dec-31-15 |
| 10-K | 10-K | 10-K | 10-K | 10-K | 10-K | 10-K | 10-K |
ASSETS | | | | | | | | |
Current assets: | | | | | | | | |
Cash and cash equivalents | 30.4 | 65.4 | 40.4 | 31.1 | 36.4 | 27.2 | 44.0 | 128.2 |
Short-term investments | 49.5 | | 12.1 | 2.5 | 30.6 | | | |
Accounts receivable, net | 15.4 | | | | | | 0.4 | 0.3 |
Inventories | 0.7 | | | | | 0.6 | 1.5 | 2.8 |
Prepaid expenses and other current assets | 3.3 | 2.9 | 1.9 | 1.9 | 1.8 | 2.4 | 2.1 | 3.7 |
Total current assets | 99.4 | 68.4 | 54.3 | 35.6 | 82.5 | 46.9 | 55.8 | 135.0 |
Property and equipment, net | | 0.2 | 0.7 | 1.2 | 1.8 | 2.4 | 3.0 | 3.7 |
Intangible assets, net | 23.2 | | | | | | | |
Other assets | 3.3 | 3.9 | 3.2 | 9.5 | 5.5 | 5.6 | 5.0 | 5.5 |
Total assets | 125.9 | 72.4 | 58.2 | 46.3 | 89.8 | 54.9 | 63.8 | 144.2 |
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LIABILITIES AND STOCKHOLDERS' (DEFICIT) EQUITY | | | | | | | | |
Current liabilities: | | | | | | | | |
Accounts payable | 2.0 | 3.9 | 1.6 | | 4.5 | 2.6 | 7.2 | 10.6 |
Accrued expenses | 29.4 | 12.7 | 7.2 | 11.6 | 12.9 | 13.9 | 24.8 | 22.1 |
Current portion of long-term debt | 47.9 | 47.4 | 4.5 | 4.8 | 4.8 | 0.4 | 7.9 | 37.4 |
Other current liabilities | 1.8 | 2.7 | 3.8 | 2.1 | 0.9 | 1.4 | 0.6 | 1.7 |
Total current liabilities | 81.1 | 66.7 | 17.0 | 18.5 | 23.1 | 19.3 | 40.6 | 72.4 |
Royalty financing obligation | 61.1 | | | | | | | |
Other liabilities | 1.2 | 2.0 | 1.2 | 5.4 | 4.6 | 5.5 | 3.6 | 4.1 |
Total liabilities | 143.5 | 68.7 | 18.2 | 28.4 | 36.9 | 38.8 | 56.1 | 96.8 |
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Commitments and contingencies (Note 14) | | | | | | | | |
Stockholders' (deficit) equity: | | | | | | | | |
Preferred stock, $0.001 par value per share: | | | | | | | | |
Common stock, $0.001 par value per share: | 0.1 | 0.1 | 0.1 | 0.1 | 0.1 | 0.0 | | |
Additional paid-in capital | 2,501.2 | 2,429.6 | 2,368.0 | 2,299.2 | 2,294.0 | 2,223.4 | | |
Accumulated other comprehensive loss | 0.0 | | 0.0 | | -10.6 | -6.3 | -6.7 | -7.0 |
Accumulated deficit | -2,518.9 | -2,425.9 | -2,328.0 | -2,275.6 | -2,224.7 | -2,195.3 | -2,150.3 | -2,098.3 |
Total stockholders' (deficit) equity | -17.6 | 3.8 | 40.0 | 17.9 | 52.9 | 16.1 | 7.8 | 47.4 |
Total liabilities and stockholders' (deficit) equity | 125.9 | 72.4 | 58.2 | 46.3 | 89.8 | 54.9 | 63.8 | 144.2 |
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Common stock authorized (in shares) | | | | | | | | |
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