| In millions, except per share items | Dec-31-22 | Jun-30-22 | Mar-31-22 | Dec-31-21 | Sep-30-21 | Jun-30-21 | Mar-31-21 | Dec-31-20 |
| | 8-K | 10-Q | 10-Q | 10-K | 10-Q | 10-Q | 10-Q | 10-K |
| CASH FLOWS FROM OPERATING ACTIVITIES: | | | | | | | | |
| Net income (loss) | | 54.1 | 39.3 | -64.1 | 10.8 | 832.1 | 790.0 | 854.0 |
| Adjustments to reconcile net income (loss) to net cash from operating activities: | | | | | | | | |
| Depreciation and amortization | | 105.4 | 107.4 | 108.0 | 109.4 | 109.2 | 107.2 | 105.2 |
| Non-cash interest expense | | 4.1 | 4.1 | 4.1 | 4.9 | 9.1 | 12.9 | 16.5 |
| Amortization of premium on investments | | 6.3 | 6.1 | 5.2 | 3.7 | 2.4 | 1.2 | 0.6 |
| Stock-based compensation | | 187.8 | 195.6 | 197.3 | 201.0 | 202.1 | 192.2 | 189.7 |
| Gain on sale of nonfinancial assets, net | | -108.0 | | | | | | -52.8 |
| Deferred income taxes | | -13.4 | -14.1 | -15.6 | -47.8 | -882.9 | -897.3 | -890.0 |
| Unrealized foreign exchange loss (gain) | | -13.1 | -12.6 | -1.8 | -2.4 | 4.8 | 2.6 | 8.0 |
| Non-cash changes in the fair value of contingent consideration | | 4.9 | 7.8 | 8.0 | 9.4 | 9.6 | 6.8 | 4.5 |
| Other | | -2.3 | -1.1 | -2.6 | -2.7 | -0.7 | -1.5 | -1.0 |
| Changes in operating assets and liabilities: | | | | | | | | |
| Accounts receivable, net | | -44.4 | -29.5 | 65.6 | 39.4 | -33.6 | 13.2 | -59.0 |
| Inventory | | -42.9 | -27.5 | -35.1 | -7.0 | -8.5 | -46.9 | -61.2 |
| Other current assets | | -16.6 | -21.0 | 29.8 | 12.5 | 32.2 | 52.8 | 18.3 |
| Other assets | | 2.2 | -6.8 | -6.6 | -23.9 | -23.1 | -26.9 | -29.0 |
| Accounts payable and other short-term liabilities | | 0.2 | 9.9 | 15.7 | -18.0 | -53.5 | -64.6 | -87.0 |
| Other long-term liabilities | | -5.5 | -3.9 | -3.3 | -16.0 | -12.4 | -9.9 | -7.0 |
| Net cash provided by operating activities | | 119.0 | 145.6 | 304.5 | 280.0 | 269.1 | 214.1 | 85.4 |
| |
| CASH FLOWS FROM INVESTING ACTIVITIES: | | | | | | | | |
| Purchases of property, plant and equipment | | -103.4 | -98.9 | -95.6 | -97.9 | -95.7 | -99.3 | -114.3 |
| Maturities and sales of investments | | 653.7 | 652.2 | 691.0 | 712.7 | 734.7 | 655.8 | 555.8 |
| Purchases of investments | | -1,241.9 | | -1,421.7 | | -1,014.2 | | -529.7 |
| Proceeds from sale of nonfinancial assets | | | 110.0 | | | | | |
| Purchase of intangible assets | | -20.0 | -22.8 | -23.6 | -16.9 | -18.8 | -22.5 | -23.2 |
| Other | | | | | -1.0 | -0.9 | | -0.7 |
| Net cash used in investing activities | | -117.2 | -207.7 | -366.3 | -299.9 | -73.3 | -201.8 | -53.6 |
| |
| CASH FLOWS FROM FINANCING ACTIVITIES: | | | | | | | | |
| Proceeds from exercises of awards under equity incentive plans | | 51.0 | 51.6 | 49.2 | 44.5 | 52.6 | 67.6 | 71.9 |
| Taxes paid related to net share settlement of equity awards | | -51.5 | -49.7 | -45.8 | -46.4 | -46.7 | -44.9 | -44.6 |
| Repayments of convertible debt | | | | | | | | -375.0 |
| Principal repayments of financing leases | | -2.2 | -2.5 | -3.0 | -3.3 | -6.8 | -8.0 | |
| Other | | | | -0.4 | -0.4 | -0.4 | | |
| Net cash provided by (used in) financing activities | | -23.7 | -1.0 | 0.0 | -380.6 | -376.3 | 176.4 | 181.1 |
| |
| Cash and cash equivalents: | | | | | | | | |
| SUPPLEMENTAL CASH FLOW DISCLOSURES: | | | | | | | | |
| Cash paid for interest | | 10.3 | 10.4 | 10.4 | 13.2 | 13.2 | 12.2 | 12.2 |
| Cash paid for income taxes | | 19.8 | 16.5 | 18.2 | 20.2 | 16.2 | 9.7 | 9.0 |
| SUPPLEMENTAL CASH FLOW DISCLOSURES FOR NON-CASH INVESTING AND FINANCING ACTIVITIES: | | | | | | | | |
| Increase (decrease) in accounts payable and accrued liabilities related to intangible assets | | | | | | | | -0.3 |