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In millions, except per share items | Dec-31-22 | Dec-31-21 | Dec-31-20 | Dec-31-19 | Dec-31-18 | Dec-31-17 | Dec-31-16 | Dec-31-15 |
| 10-K | 10-K | 10-K | 10-K | 10-K | 10-K | 10-K | 10-K |
REVENUES: | | | | | | | | |
Total revenues | 2,096.0 | 1,846.3 | 1,860.5 | 1,704.0 | 1,491.2 | 1,313.6 | 1,116.9 | 889.9 |
Total revenues growth | 13.5% | -0.8% | 9.2% | 14.3% | 13.5% | 17.6% | 25.5% | 18.8% |
OPERATING EXPENSES: | | | | | | | | |
Cost of sales | 483.7 | 470.5 | 524.3 | 359.5 | 315.3 | 241.8 | 209.6 | 152.0 |
Research and development | 649.6 | 628.8 | 628.1 | 715.0 | 696.3 | 610.8 | 661.9 | 634.8 |
Selling, general and administrative | 854.0 | 759.4 | 737.7 | 680.9 | 604.4 | 554.3 | 476.6 | 402.3 |
Intangible asset amortization and contingent consideration | 67.2 | 69.9 | 66.7 | 74.1 | 48.8 | 46.5 | -27.0 | -17.7 |
Gain on sale of nonfinancial assets, net | -108.0 | | -52.8 | -25.0 | -50.0 | -125.0 | | -369.5 |
Total operating expenses | 1,946.5 | 1,928.6 | 1,903.9 | 1,804.5 | 1,614.7 | 1,328.3 | 3,872.4 | 2,009.4 |
INCOME (LOSS) FROM OPERATIONS | 149.6 | -82.3 | -43.4 | -100.5 | -123.5 | -14.7 | -803.4 | -110.7 |
Operating margin | 7.1% | -4.5% | -2.3% | -5.9% | -8.3% | -1.1% | -71.9% | -12.4% |
Interest income | 18.0 | 10.5 | 16.6 | 22.7 | 22.8 | 14.9 | 7.5 | 4.5 |
Interest expense | -16.0 | -15.3 | -29.3 | -23.5 | -43.7 | -42.7 | -39.5 | -38.2 |
Other income (expense), net | -2.1 | 11.8 | 7.1 | 6.4 | 2.2 | 8.0 | 4.9 | -9.5 |
INCOME (LOSS) BEFORE INCOME TAXES | 149.6 | -75.4 | -49.0 | -94.8 | -142.7 | -35.9 | -831.1 | -154.7 |
Provision for (benefit from) income taxes | 8.0 | -11.3 | -903.0 | -71.0 | -65.5 | 81.2 | -200.8 | 17.1 |
NET INCOME (LOSS) | 141.6 | -64.1 | 854.0 | -23.8 | -77.2 | -117.0 | -630.2 | -171.8 |
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EARNINGS (LOSS) PER SHARE, BASIC (in dollars per share) | $0.76 | ($0.35) | $4.72 | ($0.13) | ($0.44) | ($0.67) | ($3.80) | ($1.07) |
EARNINGS (LOSS) PER SHARE, DILUTED (in dollars per share) | $0.75 | ($0.35) | $4.50 | ($0.13) | ($0.44) | ($0.67) | ($3.81) | ($1.07) |
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Weighted-average common shares outstanding, basic (in shares) | 185.3 | 182.9 | 180.8 | 179.0 | 177.1 | 174.4 | 166.0 | 160.0 |
Weighted average common shares outstanding, diluted (in shares) | 189.0 | 182.9 | 191.7 | 179.0 | 177.3 | 174.4 | 166.2 | 160.0 |
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