IOVANCE BIOTHERAPEUTICS, INC. (IOVA) [Rocket]

In millions, except per share items	Dec-31-22	Dec-31-21	Dec-31-20	Dec-31-19	Dec-31-18	Dec-31-17	Dec-31-16	Dec-31-15
	10-K	10-K	10-K	10-K	10-K	10-K	10-K	10-K
Revenues	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Cost of goods sold	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Gross profit	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Gross margin
Selling, general and administrative [+]	104.1	83.7	60.2	40.8	28.4	21.3	26.7	12.4
General and administrative	104.1	83.7	60.2	40.8	28.4	21.3	26.7	12.4
Research and development	294.8	259.0	201.7	166.0	99.8	71.6	26.9	15.5
EBITDA [+]	-389.6	-339.6	-260.8	-205.7	-127.3	-91.9	-52.7	-26.9
EBITDA growth	14.7%	30.2%	26.8%	61.6%	38.5%	74.6%	96.1%	124.7%
EBITDA margin
Depreciation and amortization	9.3	3.1	1.1	1.2	1.0	1.0	1.0	1.0
EBIT [+]	-398.9	-342.7	-261.9	-206.9	-128.3	-92.9	-53.6	-27.9
EBIT growth	16.4%	30.8%	26.6%	61.3%	38.1%	73.2%	92.5%	131.4%
EBIT margin
Interest income	3.0	0.5	2.4	9.3	4.7	0.8	0.7	0.2
Interest income	3.0	0.5	2.4	9.3	4.7	0.8	0.7	0.2
Other income (expense), net	0.0
Pre-tax income	-395.9	-342.3	-259.6	-197.6	-123.6	-92.1	-52.9	-27.7
Income taxes	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Tax rate	0.0%	0.0%	0.0%	0.0%	0.0%	0.0%	0.0%	0.0%
Net income	-395.9	-342.3	-259.6	-197.6	-123.6	-92.1	-102.3	-27.7
Net margin

Basic EPS [+]	($2.49)	($2.23)	($1.88)	($1.59)	($1.27)	($1.41)	($1.85)	($0.62)
Growth	11.4%	18.9%	18.1%	25.1%	-10.0%	-23.8%	197.3%	29.3%
Diluted EPS [+]	($2.49)	($2.23)	($1.88)	($1.59)	($1.27)	($1.41)	($1.85)	($0.62)
Growth	11.4%	18.9%	18.1%	25.1%	-10.0%	-23.8%	197.3%	29.3%

Shares outstanding (basic) [+]	159.3	153.4	138.3	124.3	97.3	65.2	55.3	44.4
Growth	3.8%	10.9%	11.2%	27.8%	49.1%	18.0%	24.4%	77.7%
Shares outstanding (diluted) [+]	159.3	153.4	138.3	124.3	97.3	65.2	55.3	44.4
Growth	3.8%	10.9%	11.2%	27.8%	49.1%	18.0%	24.4%	77.7%

EBIT is a non-GAAP figure that excludes all non-recurring expenses: restructuring costs, asset impairments, IPR&D writeoffs, and other unusual charges.