The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8

COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
Adicet Bio Inc Com 007002108   12,163,464 2,115,385 SH   DFND 1 0 2,115,385 0
Aeglea Biotherapeutics Inc Com 00773J103   69,024 240,500 SH   DFND 1 0 240,500 0
CubeSmart Com 229663109   10,191,510 220,500 SH   DFND 2 0 220,500 0
Cymabay Therapeutics Inc Com 23257D103   1,143,944 131,036 SH   DFND 1 0 131,036 0
Effector Therapeutics Inc Com 28202V108   1,687,740 4,822,114 SH   DFND 1 0 4,822,114 0
Exicure Inc Com New 30205M200   242,207 281,636 SH   DFND 1 0 281,636 0
GDS Hldgs Ltd Sponsored Ads 36165L108   75,995,171 4,072,624 SH   DFND 2,3 0 4,072,624 0
Getty Images Holdings Inc Cl A Com 374275105   60,585,339 11,902,817 SH   DFND 2 0 11,902,817 0
Hillevax Inc Com 43157M102   30,096,016 1,838,486 SH   DFND 1 0 1,838,486 0
Invitation Homes Inc Com 46187W107   14,912,325 477,500 SH   DFND 2 0 477,500 0
Jasper Therapeutics Inc Com 471871103   15,771,404 8,761,891 SH   DFND 1 0 8,761,891 0
Life Storage Inc Com 53223X107   11,273,740 86,000 SH   DFND 2 0 86,000 0
Meta Data Limited Sponsored Ads 68276W400   329,303 314,400 SH   DFND 2,3 0 314,400 0
MKS Instrs Inc Com 55306N104   292,685,452 3,302,702 SH   DFND 2,3 0 3,302,702 0
MKS Instrs Inc Com 55306N104   459,054,259 5,180,030 SH   DFND 2 0 5,180,030 0
Molecular Templates Inc Com 608550109   75,020 200,000 SH   DFND 1 0 200,000 0
Nucana Plc Sponsored Adr 67022C106   3,200,333 3,333,333 SH   DFND 1 0 3,333,333 0
Paratek Pharmaceuticals Inc Com 699374302   2,623,650 1,041,131 SH   DFND 1 0 1,041,131 0
Phathom Pharmaceuticals Inc Com 71722W107   20,868,604 2,935,106 SH   DFND 1 0 2,935,106 0
Quidelortho Corp Com 219798105   1,110,077,703 12,460,183 SH   DFND 2 0 12,460,183 0
Reneo Pharmaceuticals Inc Com 75974E103   12,236,346 2,073,957 SH   DFND 1 0 2,073,957 0
Seacor Marine Hldgs Inc Com 78413P101   9,999,867 1,314,043 SH   DFND 2 0 1,314,043 0
Sientra Inc Com 82621J204   256,058 167,358 SH   DFND 1 0 167,358 0
Smart Sh Global Ltd Ads 83193E102   5,339,331 4,810,209 SH   DFND 2,3 0 4,810,209 0
Soleno Therapeutics Inc Com 834203309   2,535,178 1,201,506 SH   DFND 1 0 1,201,506 0
Spruce Biosciences Inc Com 85209E109   6,401,305 2,896,518 SH   DFND 1 0 2,896,518 0
Vaxcyte Inc Com 92243G108   72,079,962 1,923,158 SH   DFND 1 0 1,923,158 0
Vera Therapeutics Inc Cl A 92337R101   22,882,586 2,960,231 SH   DFND 1 0 2,960,231 0
Verona Pharma Plc Sponsored Ads 925050106   49,346,600 2,457,500 SH   DFND 1 0 2,457,500 0
Vitru Ltd Com G9440D103   142,169,680 6,246,471 SH   DFND 2,3 0 6,246,471 0
ZoomInfo Technologies Inc Common Stock 98980F104   905,929,609 36,662,469 SH   DFND 2 0 36,662,469 0