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The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABEONA THERAPEUTICS INC COM NEW 00289Y206   2,678,260 869,565 SH   DFND 1 869,565 0 0
ACCOLADE INC NOTE 0.500% 4/0 00437EAB8   73,303,650 105,000,000 PRN   DFND 1 105,000,000 0 0
ACUTUS MED INC COM 005111109   3,049,417 2,651,667 SH   DFND 1 2,651,667 0 0
ADAPTHEALTH CORP COMMON STOCK 00653Q102   146,589,287 7,626,914 SH   DFND 1 7,626,914 0 0
ALECTOR INC COM 014442107   9,739,422 1,055,192 SH   DFND 1 1,055,192 0 0
ALPHATEC HLDGS INC COM NEW 02081G201   12,927,869 1,046,791 SH   DFND 1 1,046,791 0 0
AMEDISYS INC COM 023436108   94,908,123 1,136,080 SH   DFND 1 1,136,080 0 0
AMYLYX PHARMACEUTICALS INC COM 03237H101   99,506,350 2,693,000 SH   DFND 1 2,693,000 0 0
ANAPTYSBIO INC COM 032724106   36,004,988 1,161,826 SH   DFND 1 1,161,826 0 0
ANNEXON INC COM 03589W102   3,018,830 583,913 SH   DFND 1 583,913 0 0
APELLIS PHARMACEUTICALS INC NOTE 3.500% 9/1 03753UAB2   79,433,341 51,885,000 PRN   DFND 1 51,885,000 0 0
APOLLO ENDOSURGERY INC COM 03767D108   17,447,500 1,750,000 SH   DFND 1 1,750,000 0 0
ARS PHARMACEUTICALS INC COM 82835W108   94,494,717 11,077,927 SH   DFND 1 11,077,927 0 0
ALPHATEC HLDGS INC NOTE 0.750% 8/0 02081GAB8   43,668,321 48,050,000 PRN   DFND 1 48,050,000 0 0
BELLUS HEALTH INC NEW COM NEW 07987C204   29,435,820 3,581,000 SH   DFND 1 3,581,000 0 0
BROOKDALE SR LIVING INC NOTE 2.000%10/1 112463AC8   112,249,612 145,955,000 PRN   DFND 1 145,955,000 0 0
BROOKDALE SR LIVING INC COM 112463104   34,615,447 12,679,651 SH   DFND 1 12,679,651 0 0
BUTTERFLY NETWORK INC *W EXP 02/12/202 124155110   190,667 733,333 SH   DFND 1 733,333 0 0
CABALETTA BIO INC COM 12674W109   4,294,331 464,252 SH   DFND 1 464,252 0 0
CAREMAX INC COM CL A 14171W103   57,892,979 15,861,090 SH   DFND 1 15,861,090 0 0
CAREMAX INC *W EXP 06/08/202 14171W111   350,650 672,000 SH   DFND 1 672,000 0 0
CASTLE BIOSCIENCES INC COM 14843C105   6,406,058 272,135 SH   DFND 1 272,135 0 0
CATALYST PHARMACEUTICALS INC COM 14888U101   109,450,733 5,884,448 SH   DFND 1 5,884,448 0 0
CENTENE CORP DEL COM 15135B101   46,335,650 565,000 SH   DFND 1 565,000 0 0
COGENT BIOSCIENCES INC COM 19240Q201   34,290,948 2,966,345 SH   DFND 1 2,966,345 0 0
DA32 LIFE SCNCE TEC ACQSTN C CLASS A COM 23312M106   15,992,000 1,600,000 SH   DFND 1 1,600,000 0 0
DAY ONE BIOPHARMACEUTICALS I COM 23954D109   20,745,990 964,033 SH   DFND 1 964,033 0 0
DECIPHERA PHARMACEUTICALS IN COM 24344T101   38,503,847 2,349,228 SH   DFND 1 2,349,228 0 0
DENALI THERAPEUTICS INC COM 24823R105   22,248,000 800,000 SH   DFND 1 800,000 0 0
EDGEWISE THERAPEUTICS INC COM 28036F105   35,162,245 3,933,137 SH   DFND 1 3,933,137 0 0
ENHABIT INC COM 29332G102   39,427,360 2,996,000 SH   DFND 1 2,996,000 0 0
EUCRATES BIOMEDICAL ACQU COR *W EXP 10/23/202 G3141W122   18,533 333,333 SH   DFND 1 333,333 0 0
EUCRATES BIOMEDICAL ACQU COR UNIT 10/23/2027 G3141W114   10 1 SH   DFND 1 1 0 0
EVOLUS INC COM 30052C107   24,925,690 3,319,000 SH   DFND 1 3,319,000 0 0
FOGHORN THERAPEUTICS INC COM 344174107   4,960,610 777,525 SH   DFND 1 777,525 0 0
GUARDANT HEALTH INC NOTE 11/1 40131MAB5   55,784,615 89,036,000 PRN   DFND 1 89,036,000 0 0
GLAUKOS CORP NOTE 2.750% 6/1 377322AB8   312,639,806 271,752,000 PRN   DFND 1 271,752,000 0 0
GRAYBUG VISION INC COMMON 38942Q103   2,640,857 5,281,713 SH   DFND 1 5,281,713 0 0
HEALTH CATALYST INC NOTE 2.500% 4/1 42225TAB3   26,015,100 30,000,000 PRN   DFND 1 30,000,000 0 0
HILLEVAX INC COM 43157M102   45,072,310 2,694,101 SH   DFND 1 2,694,101 0 0
INTERCEPT PHARMACEUTICALS IN NOTE 3.500% 2/1 45845PAC2   95,235,195 98,354,000 PRN   DFND 1 98,354,000 0 0
IDEAYA BIOSCIENCES INC COM 45166A102   31,681,721 1,743,628 SH   DFND 1 1,743,628 0 0
IMMUNOGEN INC COM 45253H101   31,537,237 6,358,314 SH   DFND 1 6,358,314 0 0
INSMED INC COM PAR $.01 457669307   13,269,637 664,146 SH   DFND 1 664,146 0 0
INSMED INC NOTE 1.750% 1/1 457669AA7   95,820,127 102,700,000 PRN   DFND 1 102,700,000 0 0
INTERCEPT PHARMACEUTICALS IN NOTE 3.250% 7/0 45845PAA6   56,418,464 57,791,000 PRN   DFND 1 57,791,000 0 0
INVITAE CORP NOTE 2.000% 9/0 46185LAB9   190,842,634 241,873,000 PRN   DFND 1 241,873,000 0 0
IONIS PHARMACEUTICALS INC NOTE 4/0 462222AD2   118,341,522 127,800,000 PRN   DFND 1 127,800,000 0 0
IVERIC BIO INC COM 46583P102   73,326,081 3,424,852 SH   DFND 1 3,424,852 0 0
KEZAR LIFE SCIENCES INC COM 49372L100   10,067,200 1,430,000 SH   DFND 1 1,430,000 0 0
KRYSTAL BIOTECH INC COM 501147102   13,863,500 175,000 SH   DFND 1 175,000 0 0
KURA ONCOLOGY INC COM 50127T109   29,573,030 2,383,000 SH   DFND 1 2,383,000 0 0
LARIMAR THERAPEUTICS INC COM 517125100   69,967,804 16,941,357 SH   DFND 1 16,941,357 0 0
LIVONGO HEALTH INC NOTE 0.875% 6/0 539183AA1   43,769,000 50,000,000 PRN   DFND 1 50,000,000 0 0
MEDAVAIL HOLDINGS INC COM 58406B103   250,820 836,626 SH   DFND 1 836,626 0 0
MEDTECH ACQUISITION CORP UNIT 12/18/2025 58507N204   10 1 SH   DFND 1 1 0 0
MEDTECH ACQUISITION CORP *W EXP 12/22/202 58507N113   25,000 333,333 SH   DFND 1 333,333 0 0
MERUS N V COM N5749R100   36,825,376 2,380,438 SH   DFND 1 2,380,438 0 0
MIRUM PHARMACEUTICALS INC COM 604749101   39,630,533 2,032,335 SH   DFND 1 2,032,335 0 0
NATERA INC NOTE 2.250% 5/0 632307AB0   108,055,189 84,913,000 PRN   DFND 1 84,913,000 0 0
NEOGENOMICS INC NOTE 1.250% 5/0 64049MAA8   5,471,570 6,500,000 PRN   DFND 1 6,500,000 0 0
NEUROCRINE BIOSCIENCES INC COM 64125C109   180,678,560 1,512,714 SH   DFND 1 1,512,714 0 0
NEWAMSTERDAM PHARMA COMPANY ORDINARY SHARES N62509109   27,034,169 2,480,199 SH   DFND 1 2,480,199 0 0
NEWAMSTERDAM PHARMA COMPANY *W EXP 11/22/202 N62509117   80,567 92,787 SH   DFND 1 92,787 0 0
NANOSTRING TECHNOLOGIES INC NOTE 2.625% 3/0 63009RAD1   56,746,595 70,204,000 PRN   DFND 1 70,204,000 0 0
NUVALENT INC COM 670703107   595,332,695 19,991,024 SH   DFND 1 19,991,024 0 0
NUVASIVE INC NOTE 1.000% 6/0 670704AL9   95,183,765 96,966,000 PRN   DFND 1 96,966,000 0 0
NUVATION BIO INC COM CL A 67080N101   11,241,331 5,854,860 SH   DFND 1 5,854,860 0 0
NUVATION BIO INC *W EXP 07/07/202 67080N119   24,083 166,666 SH   DFND 1 166,666 0 0
NYXOAH S A SHS B6S7WD106   2,271,757 455,262 SH   DFND 1 455,262 0 0
THE ONCOLOGY INSTITUTE INC *W EXP 11/15/202 68236X118   137,625 1,250,000 SH   DFND 1 1,250,000 0 0
ONCORUS INC COM 68236R103   642,416 2,536,186 SH   DFND 1 2,536,186 0 0
1LIFE HEALTHCARE INC NOTE 3.000% 6/1 68269GAB3   39,151,240 40,599,000 PRN   DFND 1 40,599,000 0 0
ORCHARD THERAPEUTICS PLC SPON ADS 68570P101   1,172,993 3,161,707 SH   DFND 1 3,161,707 0 0
OAK STR HEALTH INC NOTE 3/1 67181AAB3   75,994,000 100,000,000 PRN   DFND 1 100,000,000 0 0
OWENS & MINOR INC NEW COM 690732102   23,025,870 1,179,000 SH   DFND 1 1,179,000 0 0
PACIRA BIOSCIENCES INC COM 695127100   11,274,120 292,000 SH   DFND 1 292,000 0 0
PACIRA BIOSCIENCES INC NOTE 0.750% 8/0 695127AF7   73,553,424 81,600,000 PRN   DFND 1 81,600,000 0 0
PEAK BIO INC *W EXP 10/26/202 70470P116   73,406 362,500 SH   DFND 1 362,500 0 0
PEPGEN INC COM 713317105   802,320 60,009 SH   DFND 1 60,009 0 0
PHREESIA INC COM 71944F106   44,214,406 1,366,329 SH   DFND 1 1,366,329 0 0
PRIME MEDICINE INC COM 74168J101   16,449,134 885,314 SH   DFND 1 885,314 0 0
PTC THERAPEUTICS INC NOTE 1.500% 9/1 69366JAD3   31,357,440 32,000,000 PRN   DFND 1 32,000,000 0 0
QUANTUM SI INC *W EXP 06/10/202 74765K113   83,333 333,333 SH   DFND 1 333,333 0 0
RAIN ONCOLOGY INC COM 75082Q105   22,370,088 2,796,261 SH   DFND 1 2,796,261 0 0
REVOLUTION MEDICINES INC COM 76155X100   21,237,602 891,587 SH   DFND 1 891,587 0 0
ROIVANT SCIENCES LTD *W EXP 09/30/202 G76279119   1,940,000 1,000,000 SH   DFND 1 1,000,000 0 0
SEMA4 HOLDINGS CORP COM CL A 81663L101   2,650,991 10,049,244 SH   DFND 1 10,049,244 0 0
SENIOR CONNECT ACQUISITN COR *W EXP 12/31/202 81723H116   30,050 500,000 SH   DFND 1 500,000 0 0
SIENTRA INC COM 82621J105   543,762 2,679,950 SH   DFND 1 2,679,950 0 0
SILK RD MED INC COM 82710M100   73,812,424 1,396,640 SH   DFND 1 1,396,640 0 0
SINGULAR GENOMICS SYSTEMS IN COM 82933R100   12,966,251 6,450,871 SH   DFND 1 6,450,871 0 0
SOMALOGIC INC *W EXP 08/31/202 83444K113   48,000 120,000 SH   DFND 1 120,000 0 0
SPRINGWORKS THERAPEUTICS INC COM 85205L107   26,868,330 1,033,000 SH   DFND 1 1,033,000 0 0
SAREPTA THERAPEUTICS INC DBCV 1.500%11/1 803607AB6   165,397,613 88,657,000 SH   DFND 1 88,657,000 0 0
SURROZEN INC *W EXP 08/01/203 86889P117   9,183 166,666 SH   DFND 1 166,666 0 0
TABULA RASA HEALTHCARE INC NOTE 1.750% 2/1 873379AA9   114,624,311 144,516,000 PRN   DFND 1 144,516,000 0 0
TARSUS PHARMACEUTICALS INC COM 87650L103   19,412,977 1,324,214 SH   DFND 1 1,324,214 0 0
TERNS PHARMACEUTICALS INC COM 880881107   29,026,102 2,851,287 SH   DFND 1 2,851,287 0 0
THE ONCOLOGY INSTITUTE INC COM 68236X100   5,544,086 3,360,052 SH   DFND 1 3,360,052 0 0
VAXCYTE INC COM 92243G108   33,565,000 700,000 SH   DFND 1 700,000 0 0
VIATRIS INC COM 92556V106   111,300,000 10,000,000 SH   DFND 1 10,000,000 0 0
VIGIL NEUROSCIENCE INC COM 92673K108   25,650,125 2,052,010 SH   DFND 1 2,052,010 0 0
XERIS BIOPHARMA HOLDINGS INC NOTE 5.000% 7/1 98422LAA5   17,094,600 18,000,000 PRN   DFND 1 18,000,000 0 0