The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
AC IMMUNE SA SHS H00263105   663,816 325,400 SH   SOLE 0 325,400 0 0
ACADIA HEALTHCARE COMPANY IN COM 00404A109   95,902,800 1,165,000 SH   SOLE 0 1,165,000 0 0
AKERO THERAPEUTICS INC COM 00973Y108   209,610,000 3,825,000 SH   SOLE 0 3,825,000 0 0
ALPINE IMMUNE SCIENCES INC COM 02083G100   7,557,270 1,028,200 SH   SOLE 0 1,028,200 0 0
ALTIMMUNE INC COM NEW 02155H200   65,635,500 3,990,000 SH   SOLE 0 3,990,000 0 0
AN2 THERAPEUTICS INC COM 037326105   7,086,508 743,600 SH   SOLE 0 743,600 0 0
ARCUTIS BIOTHERAPEUTICS INC COM 03969K108   25,974,000 1,755,000 SH   SOLE 0 1,755,000 0 0
ARGENX SE SPONSORED ADR 04016X101   236,768,750 625,000 SH   SOLE 0 625,000 0 0
ARROWHEAD PHARMACEUTICALS IN COM 04280A100   55,770,000 1,375,000 SH   SOLE 0 1,375,000 0 0
ARVINAS INC COM 04335A105   169,339,500 4,950,000 SH   SOLE 0 4,950,000 0 0
ARYA SCIENCES ACQU CORP IV CL A G31659108   5,050,000 500,000 SH   SOLE 0 500,000 0 0
ASTRAZENECA PLC SPONSORED ADR 046353108   81,360,000 1,200,000 SH   SOLE 0 1,200,000 0 0
AVIDITY BIOSCIENCES INC COM 05370A108   72,672,250 3,275,000 SH   SOLE 0 3,275,000 0 0
AXSOME THERAPEUTICS INC COM 05464T104   51,677,100 670,000 SH   SOLE 0 670,000 0 0
BELLUS HEALTH INC NEW COM NEW 07987C204   37,811,984 4,599,998 SH   SOLE 0 4,599,998 0 0
BIO RAD LABS INC CL A 090572207   38,769,178 92,200 SH   SOLE 0 92,200 0 0
BIOATLA INC COM 09077B104   10,395,000 1,260,000 SH   SOLE 0 1,260,000 0 0
BIOHAVEN LTD COM G1110E107   20,708,960 1,492,000 SH   SOLE 0 1,492,000 0 0
BIONTECH SE SPONSORED ADS 09075V102   32,357,388 215,400 SH   SOLE 0 215,400 0 0
BOSTON SCIENTIFIC CORP COM 101137107   150,687,509 3,256,700 SH   SOLE 0 3,256,700 0 0
CAREMAX INC COM CL A 14171W103   2,756,951 755,329 SH   SOLE 0 755,329 0 0
CARIBOU BIOSCIENCES INC COM 142038108   18,102,728 2,882,600 SH   SOLE 0 2,882,600 0 0
CENTURY THERAPEUTICS INC COM 15673T100   6,687,468 1,303,600 SH   SOLE 0 1,303,600 0 0
COLLEGIUM PHARMACEUTICAL INC COM 19459J104   879,234 37,898 SH   SOLE 0 37,898 0 0
COMPASS THERAPEUTICS INC COM 20454B104   10,060,000 2,000,000 SH   SOLE 0 2,000,000 0 0
CYTEIR THERAPEUTICS INC COM 23284P103   2,963,070 1,795,800 SH   SOLE 0 1,795,800 0 0
CYTOKINETICS INC COM NEW 23282W605   19,276,474 420,700 SH   SOLE 0 420,700 0 0
DECIPHERA PHARMACEUTICALS IN COM 24344T101   18,455,140 1,126,000 SH   SOLE 0 1,126,000 0 0
DEXCOM INC COM 252131107   85,700,032 756,800 SH   SOLE 0 756,800 0 0
ESSA PHARMA INC COM NEW 29668H708   4,675,608 1,855,400 SH   SOLE 0 1,855,400 0 0
FATE THERAPEUTICS INC COM 31189P102   1,055,949 104,653 SH   SOLE 0 104,653 0 0
GRAPHITE BIO INC COM 38870X104   5,229,000 1,575,000 SH   SOLE 0 1,575,000 0 0
HEALTH SCIENCES ACQ CORP 2 ORD SHS G4411D109   3,992,000 400,000 SH   SOLE 0 400,000 0 0
HYPERFINE INC COM CL A 44916K106   1,263,153 1,503,754 SH   SOLE 0 1,503,754 0 0
ICON PLC SHS G4705A100   41,763,750 215,000 SH   SOLE 0 215,000 0 0
IDEAYA BIOSCIENCES INC COM 45166A102   69,496,616 3,824,800 SH   SOLE 0 3,824,800 0 0
IMMUNOCORE HLDGS PLC ADS 45258D105   65,858,780 1,154,000 SH   SOLE 0 1,154,000 0 0
INTELLIA THERAPEUTICS INC COM 45826J105   22,266,798 638,200 SH   SOLE 0 638,200 0 0
INTRA-CELLULAR THERAPIES INC COM 46116X101   26,671,680 504,000 SH   SOLE 0 504,000 0 0
IVERIC BIO INC COM 46583P102   17,950,294 838,407 SH   SOLE 0 838,407 0 0
JAZZ PHARMACEUTICALS PLC SHS USD G50871105   115,904,557 727,541 SH   SOLE 0 727,541 0 0
KARUNA THERAPEUTICS INC COM 48576A100   58,753,500 299,000 SH   SOLE 0 299,000 0 0
KARYOPHARM THERAPEUTICS INC COM 48576U106   32,755,297 9,633,911 SH   SOLE 0 9,633,911 0 0
KEZAR LIFE SCIENCES INC COM 49372L100   47,748,096 6,782,400 SH   SOLE 0 6,782,400 0 0
KINNATE BIOPHARMA INC COM 49705R105   7,397,470 1,212,700 SH   SOLE 0 1,212,700 0 0
LEGEND BIOTECH CORP SPONSORED ADS 52490G102   48,422,400 970,000 SH   SOLE 0 970,000 0 0
LILLY ELI & CO COM 532457108   79,387,280 217,000 SH   SOLE 0 217,000 0 0
MADRIGAL PHARMACEUTICALS INC COM 558868105   124,807,500 430,000 SH   SOLE 0 430,000 0 0
MEDICUS SCIENCES ACQUISITION CL A SHS G5960S108   5,236,400 520,000 SH   SOLE 0 520,000 0 0
MEDICUS SCIENCES ACQUISITION *W EXP 02/12/202 G5960S124   5,199 57,770 SH   SOLE 0 57,770 0 0
NANOSTRING TECHNOLOGIES INC COM 63009R109   16,395,884 2,057,200 SH   SOLE 0 2,057,200 0 0
NATERA INC COM 632307104   72,261,813 1,798,900 SH   SOLE 0 1,798,900 0 0
NEUROCRINE BIOSCIENCES INC COM 64125C109   212,603,200 1,780,000 SH   SOLE 0 1,780,000 0 0
NUVATION BIO INC *W EXP 07/07/202 67080N119   14,450 99,999 SH   SOLE 0 99,999 0 0
PANACEA ACQUISITION CORP II CL A SHS G6882C106   5,025,000 500,000 SH   SOLE 0 500,000 0 0
PHATHOM PHARMACEUTICALS INC COM 71722W107   21,318,000 1,900,000 SH   SOLE 0 1,900,000 0 0
PLIANT THERAPEUTICS INC COM 729139105   43,306,932 2,240,400 SH   SOLE 0 2,240,400 0 0
POINT BIOPHARMA GLOBAL INC COM 730541109   17,732,196 2,432,400 SH   SOLE 0 2,432,400 0 0
PROMETHEUS BIOSCIENCES INC COM 74349U108   22,440,000 204,000 SH   SOLE 0 204,000 0 0
PROTHENA CORP PLC SHS G72800108   177,918,250 2,953,000 SH   SOLE 0 2,953,000 0 0
QUEST DIAGNOSTICS INC COM 74834L100   40,361,520 258,000 SH   SOLE 0 258,000 0 0
REUNION NEUROSCIENCE INC COM 76134G103   504,270 560,300 SH   SOLE 0 560,300 0 0
REVOLUTION MEDICINES INC COM 76155X100   58,954,500 2,475,000 SH   SOLE 0 2,475,000 0 0
ROCKET PHARMACEUTICALS INC COM 77313F106   29,885,093 1,527,087 SH   SOLE 0 1,527,087 0 0
SANGAMO THERAPEUTICS INC COM 800677106   8,629,662 2,748,300 SH   SOLE 0 2,748,300 0 0
SAREPTA THERAPEUTICS INC COM 803607100   136,706,900 1,055,000 SH   SOLE 0 1,055,000 0 0
SCYNEXIS INC COM NEW 811292200   1,779,336 1,140,600 SH   SOLE 0 1,140,600 0 0
SOCIAL CAP SUVRETTA HLDS CP CLASS A ORD SHS G8253Y105   2,010,000 200,000 SH   SOLE 0 200,000 0 0
SOCIAL CAP SUVRETTA HLDS CRP CLASS A ORD SHS G8253U103   2,012,000 200,000 SH   SOLE 0 200,000 0 0
SPDR SER TR S&P BIOTECH 78464A870   337,146,000 4,062,000 SH Call SOLE 0 4,062,000 0 0
SURGERY PARTNERS INC COM 86881A100   86,700,320 3,112,000 SH   SOLE 0 3,112,000 0 0
SYNDAX PHARMACEUTICALS INC COM 87164F105   149,162,450 5,861,000 SH   SOLE 0 5,861,000 0 0
SYROS PHARMACEUTICALS INC COM NEW 87184Q206   3,231,000 900,000 SH   SOLE 0 900,000 0 0
TENET HEALTHCARE CORP COM NEW 88033G407   34,997,067 717,300 SH   SOLE 0 717,300 0 0
TWIST BIOSCIENCE CORP COM 90184D100   14,547,910 611,000 SH   SOLE 0 611,000 0 0
ULTRAGENYX PHARMACEUTICAL IN COM 90400D108   138,526,700 2,990,000 SH   SOLE 0 2,990,000 0 0
UNITED THERAPEUTICS CORP DEL COM 91307C102   218,439,695 785,500 SH   SOLE 0 785,500 0 0
UNIVERSAL HLTH SVCS INC CL B 913903100   116,318,784 825,600 SH   SOLE 0 825,600 0 0
VAXCYTE INC COM 92243G108   77,458,430 1,615,400 SH   SOLE 0 1,615,400 0 0
VENTYX BIOSCIENCES INC COM 92332V107   42,135,150 1,285,000 SH   SOLE 0 1,285,000 0 0
VERTEX PHARMACEUTICALS INC COM 92532F100   49,670,160 172,000 SH   SOLE 0 172,000 0 0
VERVE THERAPEUTICS INC COM 92539P101   30,282,750 1,565,000 SH   SOLE 0 1,565,000 0 0
VIR BIOTECHNOLOGY INC COM 92764N102   21,513,500 850,000 SH   SOLE 0 850,000 0 0
ZAI LAB LTD ADR 98887Q104   961,186 31,309 SH   SOLE 0 31,309 0 0
ZENTALIS PHARMACEUTICALS INC COM 98943L107   103,721,000 5,150,000 SH   SOLE 0 5,150,000 0 0