The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | |||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | ||||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | FIGI | (to the nearest dollar) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| 2SEVENTY BIO INC | COMMON STOCK | 901384107 | BBG00YV1J631 | 3,122,571 | 333,252 | SH | DFND | 333,252 | 0 | 0 | ||
| COMPASS THERAPEUTICS INC | COM | 20454B104 | BBG00LPXKF34 | 14,233,452 | 2,829,712 | SH | DFND | 2,829,712 | 0 | 0 | ||
| CORVUS PHARMACEUTICALS INC | COM | 221015100 | BBG009F0TGJ6 | 2,026,742 | 2,384,402 | SH | DFND | 2,384,402 | 0 | 0 | ||
| CULLINAN ONCOLOGY INC | COM | 230031106 | BBG00HW2DGR3 | 35,000,089 | 3,317,544 | SH | DFND | 3,317,544 | 0 | 0 | ||
| DIREXION SHS ETF TR | DAILY S&P BIOTEC | 25460G716 | BBG0099SHGK3 | 431,250 | 25,000 | SH | DFND | 25,000 | 0 | 0 | ||
| FREELINE THERAPEUTICS HLDGS | SPONSORED ADS | 35655L107 | BBG00W5FT5H9 | 2,287,331 | 4,814,419 | SH | DFND | 4,814,419 | 0 | 0 | ||
| G1 THERAPEUTICS INC | COM | 3621LQ109 | BBG005F1DJM9 | 1,813,321 | 333,945 | SH | DFND | 333,945 | 0 | 0 | ||
| IKENA ONCOLOGY INC | COM | 45175G108 | BBG00XZY4TH8 | 4,355,409 | 1,637,372 | SH | DFND | 1,637,372 | 0 | 0 | ||
| INOZYME PHARMA INC | COM | 45790W108 | BBG00J7QJMD0 | 2,315,120 | 2,204,876 | SH | DFND | 2,204,876 | 0 | 0 | ||
| KEROS THERAPEUTICS INC | COM | 492327101 | BBG00H1HP9H8 | 10,327,133 | 215,059 | SH | DFND | 215,059 | 0 | 0 | ||
| KEZAR LIFE SCIENCES INC | COM | 49372L100 | BBG009DVZVW5 | 13,301,735 | 1,889,451 | SH | DFND | 1,889,451 | 0 | 0 | ||
| LARIMAR THERAPEUTICS INC | COM | 517125100 | BBG001V0GD97 | 14,345,001 | 3,473,366 | SH | DFND | 3,473,366 | 0 | 0 | ||
| OMEGA THERAPEUTICS INC | COMMON STOCK | 68217N105 | BBG00WCNQZQ1 | 6,029,085 | 1,055,882 | SH | DFND | 1,055,882 | 0 | 0 | ||
| ONCORUS INC | COM | 68236R103 | BBG00DDYJ7P9 | 599,672 | 2,367,436 | SH | DFND | 2,367,436 | 0 | 0 | ||
| ORCHARD THERAPEUTICS PLC | SPON ADS | 68570P101 | BBG00M62QW74 | 2,963,323 | 7,987,396 | SH | DFND | 7,987,396 | 0 | 0 | ||
| OVID THERAPEUTICS INC | COM | 690469101 | BBG009F0TD85 | 1,608,569 | 864,822 | SH | DFND | 864,822 | 0 | 0 | ||
| PLIANT THERAPEUTICS INC | COM | 729139105 | BBG00C8083P2 | 61,274,012 | 3,169,892 | SH | DFND | 3,169,892 | 0 | 0 | ||
| PLIANT THERAPEUTICS INC | COM | 729139105 | BBG00C8083P2 | 29,250 | 30,000 | SH | Call | DFND | 30,000 | 0 | 0 | |
| PRECISION BIOSCIENCES INC | COM | 74019P108 | BBG008NSBPW2 | 4,224,286 | 3,549,820 | SH | DFND | 3,549,820 | 0 | 0 | ||
| PROMETHEUS BIOSCIENCES INC | COM | 74349U108 | BBG00PPP6G63 | 101,618,000 | 923,800 | SH | DFND | 923,800 | 0 | 0 | ||
| RALLYBIO CORP | COM | 75120L100 | BBG011PFKG07 | 4,770,536 | 726,109 | SH | DFND | 726,109 | 0 | 0 | ||
| REPARE THERAPEUTICS INC | COM | 760273102 | BBG00V5N3XG2 | 41,189,854 | 2,800,126 | SH | DFND | 2,800,126 | 0 | 0 | ||
| VECTIVBIO HLDG AG | ORD SHS | H9060V101 | BBG00ZR8HCJ0 | 47,595,916 | 5,492,893 | SH | DFND | 5,492,893 | 0 | 0 | ||