The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
3M CO COM 88579Y101 3,142 28,412 SH   DFND 1 0 28,412 0
ADOBE SYSTEMS INCORPORATED COM 00724F101 5,236 19,026 SH   DFND 1 0 19,026 0
ADOBE SYSTEMS INCORPORATED COM 00724F101 1,087 3,770 SH   DFND   0 3,770 0
AIR PRODS & CHEMS INC COM 009158906 191 820 SH   DFND 1 0 820 0
AIR PRODS & CHEMS INC COM 009158906 256 1,100 SH   DFND   0 1,100 0
ALCON AG ORD SHS H01301128 1,497 25,733 SH   DFND   0 25,733 0
ALCON AG ORD SHS H01301128 4,833 83,074 SH   DFND 3 0 83,074 0
ALPHABET INC CAP STK CL A 02079K305 2,399 25,080 SH   DFND   0 25,080 0
ALPHABET INC CAP STK CL A 02079K305 2,877 30,075 SH   DFND 1 0 30,075 0
ALPHABET INC CAP STK CL C 02079K107 3,507 36,472 SH   DFND 1 0 36,472 0
AMBRX BIOPHARMA INC SPONSORED ADS 02290A102 2,087 1,932,591 SH   DFND 2 0 1,932,591 0
AMNEAL PHARMACEUTICALS INC COM STK CL A 03168L105 37,183 18,407,656 SH   DFND   0 18,407,656 0
AMNEAL PHARMACEUTICALS INC COM STK CL A 03168L105 6,290 3,113,645 SH   DFND 2 0 3,113,645 0
ANALOG DEVICES INC COM 032654105 2,554 18,330 SH   DFND 1 0 18,330 0
ANALOG DEVICES INC COM 032654105 4,754 34,117 SH   DFND 3 0 34,117 0
ANALOG DEVICES INC COM 032654105 3,621 25,900 SH   DFND   0 25,900 0
ANHEUSER BUSCH INBEV SA/NV SPONSORED ADR 03524A108 4,776 105,765 SH   DFND 3 0 105,765 0
AON PLC SHS CL A G0403H108 380 1,415 SH   DFND 1 0 1,415 0
APPLE INC COM 037833100 2,564 18,567 SH   DFND 1 0 18,567 0
AURORA MOBILE LTD ADS 051857100 8,636 8,723,205 SH   DFND   0 8,723,205 0
BECTON DICKINSON & CO COM 075887109 725 3,255 SH   DFND 1 0 3,255 0
BECTON DICKINSON & CO COM 075887109 6,981 31,330 SH   DFND 3 0 31,330 0
BECTON DICKINSON & CO COM 075887109 1,644 7,376 SH   DFND   0 7,376 0
BIONTECH SE SPONSORED ADS 09075V102 102,716 761,538 SH   DFND 2 0 761,538 0
BUTTERFLY NETWORK INC COM CL A 124155102 50,368 10,716,630 SH   DFND 2 0 10,716,630 0
CARMAX INC COM 143130102 391 5,925 SH   DFND 1 0 5,925 0
CARMAX INC COM 143130102 277 4,200 SH   DFND   0 4,200 0
CHECK CAP LTD SHS M2361E203 37 127,559 SH   DFND 2 0 127,559 0
CISCO SYS INC COM 17275R102 4,107 102,652 SH   DFND 1 0 102,652 0
CLARIVATE PLC ORD SHS G21810109 1,726 183,965 SH   DFND 1 0 183,965 0
CLARIVATE PLC ORD SHS G21810109 1,423 151,491 SH   DFND   0 151,491 0
CNH INDL N V SHS N20944109 785 69,130 SH   DFND 1 0 69,130 0
COCA COLA CO COM 191216100 3,437 61,296 SH   DFND 1 0 61,296 0
CONCORUS INC COM 68236R103 818 962,323 SH   DFND 2 0 962,323 0
CONTRAFECT CORP COM NEW 212326300 127 745,385 SH   DFND 2 0 745,385 0
CYMABAY THERAPEUTICS INC COM 23257D103 648 185,000 SH   DFND   0 185,000 0
CYMABAY THERAPEUTICS INC COM 23257D103 275 78,529 SH   DFND 3 0 78,529 0
DIAGEO PLC SPON ADR NEW 25243Q205 4,157 24,483 SH   DFND 3 0 24,483 0
DIGITALBRIDGE GROUP INC NOTE 5.000% 4/1 19624RAA4 7,959 8,000,000 SH   DFND 1 0 8,000,000 0
DISNEY WALT CO COM 254687106 1,326 14,045 SH   DFND 1 0 14,045 0
DISNEY WALT CO COM 254687106 1,682 17,827 SH   DFND   0 17,827 0
FISERV INC COM 337738108 2,679 28,633 SH   DFND 1 0 28,633 0
FISERV INC COM 337738108 4,780 51,080 SH   DFND   0 51,080 0
GALLAGHER ARTHUR J & CO COM 363576109 685 3,985 SH   DFND 1 0 3,985 0
GALLAGHER ARTHUR J & CO COM 363576109 507 2,960 SH   DFND   0 2,960 0
GLOBAL PMTS INC CALL 37940X102 820 7,585 SH   DFND 1 0 7,585 0
HELLO GROUP INC NOTE 1.250% 7/0 60879BAB3 28,662 30,523,000 SH   DFND 1 0 30,523,000 0
HUIZE HLDG LTD SPONSORED ADS 44473E105 298 350,720 SH   DFND   0 350,720 0
HYPERFINE INC COM CL A 44916K106 1,411 1,742,020 SH   DFND 2 0 1,742,020 0
INTEL CORP COM 458140100 2,259 87,627 SH   DFND 1 0 87,627 0
INTERCONTINENTAL EXCHANGE IN COM 45866F104 377 4,170 SH   DFND 1 0 4,170 0
INTERNATIONAL FLAVORS&FRAGRA COM 459506101 1,963 21,640 SH   DFND 1 0 21,640 0
INTERNATIONAL FLAVORS&FRAGRA COM 459506101 4,271 47,017 SH   DFND 3 0 47,017 0
INTERNATIONAL FLAVORS&FRAGRA COM 459506101 2,806 30,890 SH   DFND   0 30,890 0
JOHNSON & JOHNSON COM 478160104 3,594 21,977 SH   DFND 1 0 21,977 0
KLA CORP COM NEW 482480100 377 1,245 SH   DFND 1 0 1,245 0
KLA CORP COM NEW 482480100 563 1,860 SH   DFND   0 1,860 0
KONINKLIJKE PHILIPS N V NY REGIS SHS NEW 500472303 1,824 118,508 SH   DFND 3 0 118,508 0
LINDE PLC SHS G5494J103 394 1,440 SH   DFND 1 0 1,440 0
MERCK & CO INC COM 58933Y105 4,944 57,405 SH   DFND 3 0 57,405 0
MICROSOFT CORP COM 594918104 6,927 29,756 SH   DFND 1 0 29,756 0
MICROSOFT CORP COM 594918104 6,383 27,405 SH   DFND 3 0 27,405 0
MICROSOFT CORP COM 594918104 1,712 7,350 SH   DFND   0 7,350 0
NATURES SUNSHINE PRODS INC COM 639027101 24,135 2,929,001 SH   DFND 2 0 2,929,001 0
NETEASE INC SPONSORED ADS 64110W102 1,917 25,370 SH   DFND 1 0 25,370 0
NIKE INC CL B 654106103 3,232 38,889 SH   DFND 1 0 38,889 0
PFIZER INC COM 717081103 3,832 87,404 SH   DFND 1 0 87,404 0
PHILIP MORRIS INTL INC COM 718172109 6,504 78,355 SH   DFND 3 0 78,355 0
PROCTER AND GAMBLE CO COM 742718109 3,904 30,899 SH   DFND 1 0 30,899 0
QUANTUM SI INC COM CL A 74765K105 2,046 743,935 SH   DFND 2 0 743,935 0
S&P GLOBAL INC COM 78409V104 371 1,215 SH   DFND 1 0 1,215 0
SAP SE SPON ADR 803054204 4,495 55,318 SH   DFND 3 0 55,318 0
SCHWAB CHARLES CORP COM 808513105 1,393 19,380 SH   DFND 1 0 19,380 0
SCHWAB CHARLES CORP COM 808513105 1,601 22,282 SH   DFND   0 22,282 0
SERA PROGNOSTICS INC CLASS A COM 81749D107 887 554,148 SH   DFND 2 0 554,148 0
SYSCO CORP COM 871829107 400 5,655 SH   DFND 1 0 5,655 0
TAIWAN SEMICONDUCTOR MFG LTD SPONSORED ADS 874039100 4,748 69,257 SH   DFND 3 0 69,257 0
TAIWAN SEMICONDUCTOR MFG LTD SPONSORED ADS 874039100 4,100 59,800 SH   DFND   0 59,800 0
TOPBUILD CORP COM 89055F103 418 2,535 SH   DFND 1 0 2,535 0
TRIP COM GROUP LTD ADS 89677Q107 1,473 53,937 SH   DFND   0 53,937 0
TWITTER INC NOTE 3/1 90184LAN2 7,362 8,000,000 SH   DFND 1 0 8,000,000 0
UNITED PARCEL SERVICE INC CL B 911312106 3,608 22,319 SH   DFND 1 0 22,319 0
UNITEDHEALTH GROUP INC COM 91324P102 771 1,525 SH   DFND 1 0 1,525 0
VANGUARD INDEX FDS S&P 500 ETF SHS 922908363 3,879 11,818 SH   DFND 3 0 11,818 0
VERISK ANALYTICS INC COM 92345Y106 4,725 27,706 SH   DFND 3 0 27,706 0
VERISK ANALYTICS INC COM 92345Y106 1,307 7,667 SH   DFND   0 7,667 0
VERRICA PHARMACEUTICALS INC COM 92511W108 448 153,395 SH   DFND   0 153,395 0
VERRICA PHARMACEUTICALS INC COM 92511W108 377 129,013 SH   DFND 3 0 129,013 0
VIEWRAY INC COM 92672L107 388,356 14,639,136 SH   DFND   0 14,639,136 0
VISA INC COM CL A 92826C839 1,191 6,703 SH   DFND   0 6,703 0
VISA INC COM CL A 92826C839 5,710 32,127 SH   DFND 1 0 32,127 0
WEIBO CORP NOTE 1.250% 11/1 948596AC5 81,015 81,730,000 SH   DFND 1 0 81,730,000 0
WEIBO CORP NOTE 1.250% 11/1 948596AC5 991 1,000,000 SH   DFND   0 1,000,000 0
WELLS FARGO CO NEW COM 949746101 674 16,735 SH   DFND 1 0 16,735 0
WELLS FARGO CO NEW COM 949746101 740 18,400 SH   DFND   0 18,400 0
WYNDHAM HOTELS & RESORTS INC COM 98311A105 688 11,200 SH   DFND 1 0 11,200 0
WYNDHAM HOTELS & RESORTS INC COM 98311A105 507 8,260 SH   DFND   0 8,260 0